Page last updated: 2024-12-06
comenic acid
Description
Comenic acid, also known as 5-hydroxy-4-pyrone-2-carboxylic acid, is a naturally occurring compound found in fungi. It is a white crystalline solid that is soluble in water and alcohol. Comenic acid is a potent antioxidant and has been shown to have a number of pharmacological activities, including anti-inflammatory, anti-bacterial, and anti-cancer properties. The compound is synthesized through the fermentation of Aspergillus niger, a type of fungus. It is a precursor to the synthesis of other compounds, such as kojic acid. Its strong antioxidant activity has made it a subject of interest for research. Researchers are investigating its potential as a therapeutic agent for various diseases, including cancer and inflammatory conditions. Comenic acid has also been studied for its ability to inhibit the growth of bacteria and fungi.'
comenic acid: an ingredient of Baliz-2 that may have antibacterial and antioxidant activities [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 68139 |
| CHEMBL ID | 177875 |
| SCHEMBL ID | 1171093 |
| MeSH ID | M0470505 |
Synonyms (26)
| Synonym |
|---|
| comenic acid |
| 5-hydroxy-4-oxo-4h-pyran-2-carboxylic acid |
| AO-801/41077391 |
| 5-hydroxy-4-oxo-4h-pyran-2-carboxylic acid, 97% |
| uuuicommfftchs-uhfffaoysa- |
| inchi=1/c6h4o5/c7-3-1-5(6(9)10)11-2-4(3)8/h1-2,8h,(h,9,10) |
| KUC106763N |
| ksc-11-228-7 |
| 5-hydroxy-4-oxopyran-2-carboxylic acid |
| FT-0665161 |
| CHEMBL177875 |
| 499-78-5 |
| AKOS005266560 |
| einecs 207-891-7 |
| 4h-pyran-2-carboxylic acid, 5-hydroxy-4-oxo- |
| A827917 |
| 5-hydroxy-4-oxo-pyran-2-carboxylic acid;5-hydroxy-4-oxo-4h-pyran-2-carboxylic acid |
| 2-carboxy-5-hydroxy-4-pyrone |
| SCHEMBL1171093 |
| DTXSID4060103 |
| UUUICOMMFFTCHS-UHFFFAOYSA-N |
| 2-carboxy-5-hydroxypyran-4-one |
| mfcd03085981 |
| 5-hydroxy-4-oxo-4h-pyran-2-carboxylic |
| 5-hydroxy-4-oxo-4h-pyran-2-carboxylicacid |
| BS-38124 |
Research Excerpts
Treatment
Research
Studies (15)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 11 (73.33) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 21.85
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 21.85 (24.57) | | Research Supply Index | 2.77 (2.92) | | Research Growth Index | 5.32 (4.65) | | Search Engine Demand Index | 18.60 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 15 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |