buquineran: cardiac stimulant; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 71953 |
| CHEMBL ID | 26984 |
| SCHEMBL ID | 783795 |
| MeSH ID | M0059915 |
| Synonym |
|---|
| uk-14275 |
| bdpu |
| buquineran |
| 1-butyl-3-(1-(6,7-dimethoxyquinazolin-4-yl)piperidin-4-yl)urea |
| buquineranum [inn-latin] |
| 1-butyl-3-(1-(6,7-dimethoxy-4-quinazolinyl)-4-piperidyl)urea |
| urea, 1-butyl-3-(1-(6,7-dimethoxyquinazolin-4-yl)piperidin-4-yl)- |
| urea, n-butyl-n'-(1-(6,7-dimethoxy-4-quinazolinyl)-4-piperidinyl)- |
| brn 0717450 |
| CHEMBL26984 |
| 1-butyl-3-[1-(6,7-dimethoxyquinazolin-4-yl)piperidin-4-yl]urea |
| 59184-78-0 |
| buquineran [inn:ban] |
| unii-awc1vms3hc |
| buquineranum |
| awc1vms3hc , |
| 5-25-13-00341 (beilstein handbook reference) |
| buquineran [inn] |
| buquineran [mart.] |
| SCHEMBL783795 |
| DTXSID30207924 |
| Q27274151 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID40531 | Positive inotropic effects by direct or indirect beta-1 adrenergic receptor activation. | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2 | In search of the digitalis replacement. |
| AID220009 | Inhibition of cAMP Phosphodiesterase enzyme. | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2 | In search of the digitalis replacement. |
| AID218884 | Electrophysiological activity as concentration causing 20 % increase in the functional refractory period of canine ventricular muscle. | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8 | Cardiotonic agents. 1. Novel 8-aryl-substituted imidazo[1,2-a]- and -[1,5-a]pyridines and imidazo[1,5-a]pyridinones as potential positive inotropic agents. |
| AID219073 | Inotropic activity as dose required to cause 20% positive or negative change in contractile force of papillary muscle from ferret | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8 | Cardiotonic agents. 1. Novel 8-aryl-substituted imidazo[1,2-a]- and -[1,5-a]pyridines and imidazo[1,5-a]pyridinones as potential positive inotropic agents. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 1 (8.33%) | 5.53% |
| Reviews | 3 (25.00%) | 6.00% |
| Case Studies | 1 (8.33%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (58.33%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||