1-decyl methyl sulfoxide profile

1-Decyl methyl sulfoxide (also known as **decyl methyl sulfoxide** or **DMS**O) is an organic compound with the formula **CH3SOCH2(CH2)9CH3**. It's a colorless, odorless liquid that is often used as a solvent in various research applications.

Here's why it's important for research:

* **Solvent Properties:** DMS is an excellent solvent for both organic and inorganic compounds. It has a high dielectric constant and can dissolve a wide range of polar and nonpolar substances. This makes it useful for carrying out chemical reactions, separating compounds, and studying the properties of various materials.

* **Pharmaceutical Applications:** DMSO has been explored for its potential therapeutic benefits. It can penetrate the skin easily and deliver drugs, making it a potential agent for transdermal drug delivery. It's also been studied for its anti-inflammatory, analgesic, and antioxidant properties.

* **Biological Research:** DMS is used in cell culture and biological research to help cells take up various compounds, including drugs, DNA, and other molecules. This property makes it a valuable tool for studying cellular processes, drug efficacy, and gene therapy.

* **Spectroscopy and Chromatography:** DMS can be used as a solvent in various spectroscopic techniques, like NMR and IR spectroscopy. It can also be used in chromatography to separate and purify compounds.

**Important Considerations:**

* **Toxicity:** While DMSO is considered relatively safe, it can cause skin irritation and allergic reactions in some individuals. It's important to handle it with caution and follow appropriate safety protocols.
* **Purity:** The purity of DMSO is crucial for research applications. Impurities can interfere with experiments and affect the results.
* **Regulatory Status:** The regulatory status of DMSO varies depending on the application and country. It's important to check local regulations before using it for any specific purpose.

In conclusion, 1-decyl methyl sulfoxide is a versatile compound with various applications in research. Its unique properties make it a valuable tool for studying chemistry, biology, and medicine. However, it's important to use it responsibly and be aware of its potential hazards.

1-decyl methyl sulfoxide: penetrant enhancer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	65111
SCHEMBL ID	29144
MeSH ID	M0153350

Synonym
1-(methylsulfinyl)decane
3079-28-5
decyl methyl sulfoxide
1-methylsulfinyldecane
einecs 221-368-0
gkv59f869b ,
1-decyl methyl sulfoxide
unii-gkv59f869b
decane, 1-(methylsulfinyl)-
n-decylmethyl sulfoxide
1-(methylsulphinyl)decane
n-decylmethylsulfoxide
n-decyl-methyl sulphoxide
decyl methyl sulphoxide
n-decyl-methyl sulfoxide
decyl methyl sulfoxide [ii]
SCHEMBL29144
decylmethyl sulfoxide
NZJXADCEESMBPW-UHFFFAOYSA-N
sulfoxide, decyl methyl
FT-0699755
DTXSID60863097
Q27279150
decylmethylsulfoxide
AKOS040749897

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	4 (44.44)	18.7374
1990's	5 (55.56)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	9 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
dimethyl sulfoxide Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.. dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.	3.58	9	sulfoxide; volatile organic compound	alkylating agent; antidote; Escherichia coli metabolite; geroprotector; MRI contrast agent; non-narcotic analgesic; polar aprotic solvent; radical scavenger
propylene glycol Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.. propane-1,2-diol : The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze.	1.97	1	glycol; propane-1,2-diols	allergen; human xenobiotic metabolite; mouse metabolite; protic solvent
fluorouracil Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.. 5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.	2.37	2	nucleobase analogue; organofluorine compound	antimetabolite; antineoplastic agent; environmental contaminant; immunosuppressive agent; radiosensitizing agent; xenobiotic
lidocaine Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.. lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.	1.97	1	benzenes; monocarboxylic acid amide; tertiary amino compound	anti-arrhythmia drug; drug allergen; environmental contaminant; local anaesthetic; xenobiotic
methadone Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3). methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.. 6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.	1.99	1	benzenes; diarylmethane; ketone; tertiary amino compound
propranolol Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.. propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.	1.97	1	naphthalenes; propanolamine; secondary amine	anti-arrhythmia drug; antihypertensive agent; anxiolytic drug; beta-adrenergic antagonist; environmental contaminant; human blood serum metabolite; vasodilator agent; xenobiotic
zidovudine Zidovudine: A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia.. zidovudine : A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.	1.97	1	azide; pyrimidine 2',3'-dideoxyribonucleoside	antimetabolite; antiviral drug; HIV-1 reverse transcriptase inhibitor
laurocapram laurocapram: enhances percutaneous absorption of different chemicals; structure given in first source	2.67	3
oleic acid Oleic Acid: An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed). oleic acid : An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.	2.37	2	octadec-9-enoic acid	antioxidant; Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; Escherichia coli metabolite; mouse metabolite; plant metabolite; solvent
enkephalin, leucine Enkephalin, Leucine: One of the endogenous pentapeptides with morphine-like activity. It differs from MET-ENKEPHALIN in the LEUCINE at position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.. Leu-enkephalin : A pentapeptide comprising L-tyrosine, glycine, glycine, L-phenylalanine and L-leucine residues joined in sequence by peptide linkages. It is an endogenous opioid peptide produced in vertebrate species, including rodents, primates and humans that results from decomposition of proenkephalin or dynorphin and exhibits antinociceptive properties.	1.97	1	pentapeptide; peptide zwitterion	analgesic; delta-opioid receptor agonist; human metabolite; mu-opioid receptor agonist; neurotransmitter; rat metabolite
cyclosporine Cyclosporine: A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).	1.98	1
acyclovir Acyclovir: A GUANOSINE analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes.. acyclovir : An oxopurine that is guanine substituted by a (2-hydroxyethoxy)methyl substituent at position 9. Used in the treatment of viral infections.	1.97	1	2-aminopurines; oxopurine	antimetabolite; antiviral drug

1-decyl methyl sulfoxide

Description

Cross-References

Synonyms (25)

Research

Studies (9)

Market Indicators

Research Demand Index: 12.19

Study Types