Compounds > myomodulin
Page last updated: 2024-09-25

myomodulin

Description

myomodulin: found in motor neuron B16 of Aplysia; amino acid sequence given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID123654
MeSH IDM0150988

Synonyms (7)

Synonym
myomodulin
(2s)-n-[(2s)-1-[[(2s)-1-[[(2s)-1-[[(2s)-1-[[(2s)-1-[[(2s)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amin
myomoduline a (aplysia californica)
110570-93-9
HY-P0268
myomodulin a(aplysiacalifornica)(9ci)
AKOS040764116

Effects

ExcerptReference
"A myomodulin peptide has been suggested to mediate the response of the giant glial cells to stimulation of the Leydig interneuron in the central nervous system of the leech Hirudo medicinalis [Eur. "( Britz, FC; Deitmer, JW, 2002)
"Myomodulin A has no consistent effect on the tension induced by the fast extensor motoneurone (FETi) or upon the myogenic rhythm present in the extensor."( Evans, PD, 1994)

Research

Studies (46)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (4.35)18.7374
1990's32 (69.57)18.2507
2000's10 (21.74)29.6817
2010's2 (4.35)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (2.04%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other48 (97.96%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
fmrfamide[no description available]medium100
allatostatin 1[no description available]medium10
allatotropin[no description available]medium10
4-aminopyridine[no description available]medium20aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker
buccalin[no description available]medium110
benfluorex[no description available]medium10benzoate ester
fenfluramine[no description available]medium10(trifluoromethyl)benzenes;
secondary amino compound		appetite depressant;
serotonergic agonist;
serotonin uptake inhibitor
cesium[no description available]medium10alkali metal atom
cesium chloride[no description available]medium10inorganic caesium salt;
inorganic chloride		phase-transfer catalyst;
vasoconstrictor agent
ouabain[no description available]medium1011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
chlorine[no description available]medium10halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
small cardioactive peptide a[no description available]medium30
small cardioactive peptide b[no description available]medium40
methionine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
choline[no description available]medium10cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
achatin i[no description available]medium10
lucifer yellow[no description available]medium20organic lithium saltfluorochrome
enkephalin, methionine[no description available]medium10
lysine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
biocytin[no description available]medium10azabicycloalkane;
L-alpha-amino acid zwitterion;
L-lysine derivative;
monocarboxylic acid amide;
non-proteinogenic L-alpha-amino acid;
thiabicycloalkane;
ureas		mouse metabolite
hexamethonium[no description available]medium20quaternary ammonium salt
arginylphenylalaninamide[no description available]medium10
methysergide[no description available]medium10ergoline alkaloid
benzoquinonium[no description available]medium10aromatic amine
tetraethylammonium[no description available]medium10quaternary ammonium ion
tetrodotoxin[no description available]medium10azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid		animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker
arachidonic acid[no description available]medium10icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Aging0low10
Muscle Contraction0low110
Muscle Relaxation0low10

Research Highlights

Onset of Action (1)

ArticleYear
Modulatory effects of serotonin, FMRFamide, and myomodulin on the duration of action potentials, excitability, and membrane currents in tail sensory neurons of Aplysia.
Journal of neurophysiology, Volume: 66, Issue: 6		1991
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (1)

ArticleYear
Functional redundancy of FMRFamide-related peptides at the Drosophila larval neuromuscular junction.
The Journal of neuroscience : the official journal of the Society for Neuroscience, Sep-15, Volume: 18, Issue: 18		1998
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]