| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain H, Proteasome component PUP1 | 0 | 1 | 0 | 1 |
| Chain I, Proteasome component PUP3 | 0 | 1 | 0 | 1 |
| Chain K, Proteasome component PRE2 | 0 | 1 | 0 | 1 |
| Chain L, Proteasome component C5 | 0 | 1 | 0 | 1 |
| Chain K, Proteasome component PRE2 | 0 | 1 | 0 | 1 |
| Chain L, Proteasome component C5 | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-11 | 0 | 1 | 0 | 1 |
| RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
| Fumarate hydratase | 2 | 0 | 0 | 2 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| TDP1 protein | 3 | 0 | 0 | 3 |
| AR protein | 3 | 0 | 0 | 3 |
| caspase 7, apoptosis-related cysteine protease | 2 | 0 | 0 | 2 |
| estrogen receptor 2 (ER beta) | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | 3 | 0 | 0 | 3 |
| progesterone receptor | 3 | 0 | 0 | 3 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 3 | 0 | 0 | 3 |
| retinoid X nuclear receptor alpha | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 3 | 0 | 0 | 3 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 3 | 0 | 0 | 3 |
| polyprotein | 2 | 0 | 0 | 2 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 3 | 0 | 0 | 3 |
| caspase-3 | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| Caspase-7 | 2 | 0 | 0 | 2 |
| caspase-3 | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 3 | 0 | 0 | 3 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 3 | 0 | 0 | 3 |
| 26S proteasome non-ATPase regulatory subunit 11 | 0 | 1 | 0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 12 | 0 | 1 | 0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 14 | 0 | 1 | 0 | 1 |
| Proteasome subunit alpha type-7 | 0 | 1 | 0 | 1 |
| Histone deacetylase 3 | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 2 | 0 | 2 |
| Multidrug resistance-associated protein 4 | 0 | 2 | 0 | 2 |
| 26S proteasome non-ATPase regulatory subunit 3 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 12 | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Prothrombin | 0 | 1 | 0 | 1 |
| Chymotrypsinogen A | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Interferon beta | 2 | 0 | 0 | 2 |
| Cellular tumor antigen p53 | 3 | 0 | 0 | 3 |
| Carbonic anhydrase 3 | 0 | 1 | 0 | 1 |
| Cathepsin B | 0 | 1 | 0 | 1 |
| Neutrophil elastase | 0 | 1 | 0 | 1 |
| Cathepsin G | 0 | 2 | 0 | 2 |
| Lysosomal protective protein | 0 | 1 | 0 | 1 |
| Chymotrypsinogen B | 0 | 1 | 0 | 1 |
| 26S proteasome regulatory subunit 6A | 0 | 1 | 0 | 1 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Nuclear factor NF-kappa-B p105 subunit | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-1 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 4 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 6 | 0 | 1 | 0 | 1 |
| Chymase | 0 | 1 | 0 | 1 |
| Proteasome subunit alpha type-1 | 0 | 1 | 0 | 1 |
| Proteasome subunit alpha type-2 | 0 | 1 | 0 | 1 |
| Proteasome subunit alpha type-3 | 0 | 1 | 0 | 1 |
| Proteasome subunit alpha type-4 | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-8 | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-8 | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-9 | 0 | 1 | 0 | 1 |
| Proteasome subunit alpha type-5 | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-4 | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-6 | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-5 | 0 | 2 | 0 | 3 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 1 | 0 | 1 |
| 26S proteasome regulatory subunit 7 | 0 | 1 | 0 | 1 |
| Lon protease homolog, mitochondrial | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-10 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 7 | 0 | 1 | 0 | 1 |
| 26S proteasome regulatory subunit 6B | 0 | 1 | 0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 8 | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-3 | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-2 | 0 | 1 | 0 | 2 |
| 26S proteasome non-ATPase regulatory subunit 7 | 0 | 1 | 0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 4 | 0 | 1 | 0 | 1 |
| 26S proteasome complex subunit SEM1 | 0 | 1 | 0 | 1 |
| Proteasome subunit alpha type-6 | 0 | 1 | 0 | 1 |
| 26S proteasome regulatory subunit 4 | 0 | 1 | 0 | 1 |
| 26S proteasome regulatory subunit 8 | 0 | 1 | 0 | 1 |
| 26S proteasome regulatory subunit 10B | 0 | 1 | 0 | 1 |
| Beta-carbonic anhydrase 1 | 0 | 1 | 0 | 1 |
| Nuclear factor NF-kappa-B p100 subunit | 0 | 1 | 0 | 1 |
| Transcription factor p65 | 0 | 1 | 0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 2 | 0 | 1 | 0 | 1 |
| Histone deacetylase 1 | 0 | 1 | 0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 6 | 0 | 1 | 0 | 1 |
| Proteasomal ubiquitin receptor ADRM1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 9 | 0 | 1 | 0 | 1 |
| ATP-dependent Clp protease proteolytic subunit | 0 | 1 | 1 | 2 |
| Carbonic anhydrase 13 | 0 | 1 | 0 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | 0 | 1 | 0 | 1 |
| Proteasome subunit alpha-type 8 | 0 | 1 | 0 | 1 |
| Histone deacetylase 2 | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Proteasome subunit beta type-7 | 0 | 1 | 0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 1 | 0 | 1 | 0 | 1 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| Carbonic anhydrase 15 | 0 | 1 | 0 | 1 |
| Histone deacetylase 8 | 0 | 1 | 0 | 1 |
| Histone deacetylase 6 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 14 | 0 | 1 | 0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 13 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5B, mitochondrial | 0 | 1 | 0 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| GLS protein | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
| thioredoxin glutathione reductase | 2 | 0 | 0 | 2 |
| Smad3 | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
| G | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| glucocerebrosidase | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| importin subunit beta-1 isoform 1 | 1 | 0 | 0 | 1 |
| snurportin-1 | 1 | 0 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| geminin | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| Atrial natriuretic peptide receptor 1 | 0 | 1 | 0 | 1 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| Glucocorticoid receptor | 0 | 2 | 1 | 3 |
| Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |