Page last updated: 2024-09-26

purpurin 18

Description

purpurin 18: isolated from chlorophyll; structure given in first source; RN from Chemical Abstracts Index Guide [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID161493
CHEMBL ID499696
SCHEMBL ID272202
MeSH IDM0164417

Synonyms (20)

Synonym
purpurin 18
CHEMBL499696
puppurin 18
pp-18
21h,23h-porphine-2,20-dicarboxylic acid, 18-(2-carboxyethyl)-12-ethenyl-7-ethyl-17,18-dihydro-3,8,13,17-tetramethyl-, cyclic 2,20-anhydride, (17s-trans)-
purpurin-18
SCHEMBL272202
purpurin18
(17s-trans)-18-(2-carboxyethyl)-12-ethenyl-7-ethyl-17,18-dihydro-3,8,13,17-tetramethyl-21h,23h-porphine-2,20-dicarboxylic acid cyclic 2,20-anhydride
J-016002
RNKGDBZSPISIRN-JXFKEZNVSA-N
pyrpurin-18
HY-128972
3-[(22s,23s)-17-ethenyl-12-ethyl-13,18,22,27-tetramethyl-3,5-dioxo-4-oxa-8,24,25,26-tetrazahexacyclo[19.2.1.16,9.111,14.116,19.02,7]heptacosa-1,6,9(27),10,12,14(26),15,17,19(25),20-decaen-23-yl]propanoic acid
BCP10887
CS-0102953
A936488
(17s,18s)-18-(2-carboxyethyl)-12-vinyl-7-ethyl-17,18-dihydro-3,8,13,17-tetramethyl-21h,23h-porphyrin-2,20-dicarboxylic acid 2,20-anhydride
AT38721
AKOS040744352

Research

Studies (23)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (4.35)18.7374
1990's0 (0.00)18.2507
2000's11 (47.83)29.6817
2010's10 (43.48)24.3611
2020's1 (4.35)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other25 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research Highlights

Safety/Toxicity (2)

ArticleYear
Conjugation of chlorins with spermine enhances phototoxicity to cancer cells in vitro.
Journal of photochemistry and photobiology. B, Biology, Volume: 168
2017
Pharmacokinetics and phototoxicity of purpurin-18 in human colon carcinoma cells using liposomes as delivery vehicles.
Cancer chemotherapy and pharmacology, Volume: 57, Issue: 4
2006
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (1)

ArticleYear
Pharmacokinetics and phototoxicity of purpurin-18 in human colon carcinoma cells using liposomes as delivery vehicles.
Cancer chemotherapy and pharmacology, Volume: 57, Issue: 4
2006
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Interactions (1)

ArticleYear
Purpurin-18 in combination with light leads to apoptosis or necrosis in HL60 leukemia cells.
Photochemistry and photobiology, Volume: 73, Issue: 3
2001
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]