Compounds > fr 122047
Page last updated: 2024-09-05

fr 122047 and indomethacin

fr 122047 has been researched along with indomethacin in 2 studies

Compound Research Comparison

Studies
(fr 122047)		Trials
(fr 122047)		Recent Studies (post-2010)
(fr 122047)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
60329,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomyfr 122047 (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harada, S; Kakuta, H; Oda, H; Sasaki, K; Sugimoto, Y; Tai, A; Zheng, X1
Alcaro, S; Angeli, A; Angius, R; Bianco, G; Capasso, C; Cottiglia, F; Del Prete, S; Deplano, S; Distinto, S; Fois, B; Gaspari, M; Maccioni, E; Meleddu, R; Melis, C; Ortuso, F; Supuran, CT; Taverna, D; Yanez, M1

Other Studies

2 other study(ies) available for fr 122047 and indomethacin

ArticleYear
Cyclooxygenase-1-selective inhibitors are attractive candidates for analgesics that do not cause gastric damage. design and in vitro/in vivo evaluation of a benzamide-type cyclooxygenase-1 selective inhibitor.
    Journal of medicinal chemistry, 2008, Apr-24, Volume: 51, Issue:8

    Topics: Aminopyridines; Animals; Benzamides; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Molecular Structure; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Stomach

2008
Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides.
    ACS medicinal chemistry letters, 2018, Oct-11, Volume: 9, Issue:10

    Topics:

2018