Page last updated: 2024-12-05

basic blue k

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Basic Blue K, also known as Methyl Violet 10B, is a triarylmethane dye with the chemical formula C24H25ClN2. It is synthesized through the reaction of dimethylaniline with benzaldehyde and hydrochloric acid. It is a cationic dye that exhibits a deep blue color in solution. Basic Blue K is widely used as a biological stain, particularly in microscopy and histology, where it stains nuclei and cytoplasm. It is also employed in the textile industry as a dye for wool and silk. Due to its strong absorption properties, Basic Blue K is studied for potential applications in areas like photodynamic therapy, where it can be used to target and destroy cancer cells upon irradiation. Its use as an antimicrobial agent is also being explored. Despite its extensive applications, Basic Blue K is considered toxic and should be handled with care.'

Basic Blue K: RN given refers to chloride [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

victoria blue R : An iminium salt composed of 4-{[4-(dimethylamino)phenyl][4-(ethylamino)naphthalen-1-yl]methylidene}-N,N-dimethylcyclohexa-2,5-dien-1-iminium and chloride ions in a 1:1 ratio. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID16599
CHEBI ID90518
SCHEMBL ID125523
SCHEMBL ID2856656
SCHEMBL ID23064844
SCHEMBL ID23064843
MeSH IDM0106891

Synonyms (40)

Synonym
methanaminium, n-[4-[[4-(dimethylamino)phenyl][4-(ethylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-n-methyl-, chloride
nsc11240
victoria blue r
2185-86-6
basic blue k
victoria lake blue r
c.i. 44040
aizen victoria blue boh
hidaco victoria blue r
c.i. basic blue 11
nsc-11240
victoria blue rs
methanaminium, n-(4-((4-(dimethylamino)phenyl)(4-(ethylamino)-1-naphthalenyl)methylene)-2,5-cyclohexadien-1-ylidene)-n-methyl-, chloride
n,n'-(n,n'-tetramethyl)-1-diaminodiphenylnaphthylaminomethane hydrochloride
nsc 11240
einecs 218-572-7
ci 44040
(4-((4-(dimethylamino)phenyl)(4-(ethylamino)-1-naphthyl)methylene)cyclohexa-2,5-dien-1-ylidene)dimethylammonium chloride
victoria blue r, dye content 80 %
AKOS000283093
basic blue 11
methanaminium, n-(4-((4-(dimethylamino)phenyl)(4-(ethylamino)-1-naphthalenyl)methylene)-2,5-cyclohexadien-1-ylidene)-n-methyl-, chloride (1:1)
AKOS015901187
4-{[4-(dimethylamino)phenyl][4-(ethylamino)naphthalen-1-yl]methylidene}-n,n-dimethylcyclohexa-2,5-dien-1-iminium chloride
SCHEMBL125523
SCHEMBL2856656
W-107515
CHEBI:90518
mfcd00011876
AKOS030241786
vic-toria blue r
n-(4-((4-(dimethylamino)phenyl)(4-(ethylamino)naphthalen-1-yl)methylene)cyclohexa-2,5-dienylidene)-n-methylmethanaminium chloride
victoriabluer
Q7927164
n-(4-((4-(dimethylamino)phenyl)(4-(ethylamino)naphthalen-1-yl)methylene)cyclohexa-2,5-dien-1-ylidene)-n-methylmethanaminium chloride
[4-[bis[4-(dimethylamino)phenyl]methylidene]naphthalen-1-ylidene]-ethylazanium;chloride
DTXSID90883804
[4-[bis[4-(dimethylamino)phenyl]methylidene]naphthalen-1-ylidene]-ethylazanium chloride
SCHEMBL23064844
SCHEMBL23064843
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
histological dyeA dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.
fluorochromeA fluorescent dye used to stain biological specimens.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
iminium saltSalts in which the cation has the structure R2C=N(+)R2. Thus N-hydronated imines and their N-substituted derivatives.
organic chloride salt
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (22.22)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.86

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.86 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index5.17 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.86)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]