Page last updated: 2024-09-27

Opium Abuse

Strong physiological and emotional dependence on OPIUM.

Synonyms(5)

Synonym
Opium Dependence
Opium Abuse
Opium Addiction
Opium Smoking
Opium Use

Research Excerpts

Research

Studies (22)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's12 (54.55)28.8240
2020's10 (45.45)9.53
DrugIndicatedRelationship StrengthStudiesTrials
clonazepam0low10
methadone0medium11
thyroxine0low10
triiodothyronine0low10
mercury0low10
tramadol0low10
lead0low130
barium0low10

Protein Targets (134)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Gamma-aminobutyric acid receptor subunit pi0303
Gamma-aminobutyric acid receptor subunit pi0112
Gamma-aminobutyric acid receptor subunit delta0303
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Neuronal acetylcholine receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-10303
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit beta-10303
Gamma-aminobutyric acid receptor subunit delta0112
Gamma-aminobutyric acid receptor subunit gamma-20303
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit alpha-50112
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit gamma-10112
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit beta-30303
Gamma-aminobutyric acid receptor subunit gamma-30112
Gamma-aminobutyric acid receptor subunit alpha-60112
Translocator protein0101
Translocator protein0101
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
Gamma-aminobutyric acid receptor subunit alpha-50303
Gamma-aminobutyric acid receptor subunit alpha-30303
Gamma-aminobutyric acid receptor subunit alpha-20303
Gamma-aminobutyric acid receptor subunit beta-20303
Gamma-aminobutyric acid receptor subunit alpha-40303
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit beta-20112
Gamma-aminobutyric acid receptor subunit epsilon0303
Gamma-aminobutyric acid receptor subunit alpha-60303
Gamma-aminobutyric acid receptor subunit gamma-10303
GABA theta subunit0112
Gamma-aminobutyric acid receptor subunit gamma-30303
Gamma-aminobutyric acid receptor subunit epsilon0112
Gamma-aminobutyric acid receptor subunit theta0303
Voltage-dependent L-type calcium channel subunit alpha-1F0101
ATP-dependent translocase ABCB10101
D(2) dopamine receptor0101
Cytochrome P450 2B60101
D(4) dopamine receptor0101
Mu-type opioid receptor0314
D(3) dopamine receptor0101
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Potassium voltage-gated channel subfamily H member 20101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Mas-related G-protein coupled receptor member X20011
Aldehyde oxidase 1 0101
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
thioredoxin reductase1001
RAR-related orphan receptor gamma1001
USP1 protein, partial2002
TDP1 protein3003
apical membrane antigen 1, AMA12002
nuclear receptor subfamily 1, group I, member 31001
cytochrome P450 family 3 subfamily A polypeptide 42002
EWS/FLI fusion protein1001
estrogen-related nuclear receptor alpha2002
pregnane X nuclear receptor2002
estrogen nuclear receptor alpha2002
G1001
peroxisome proliferator-activated receptor delta1001
peroxisome proliferator activated receptor gamma2002
euchromatic histone-lysine N-methyltransferase 21001
aryl hydrocarbon receptor2002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a2002
v-jun sarcoma virus 17 oncogene homolog (avian)1001
thyroid hormone receptor beta isoform a2002
thyroid hormone receptor beta isoform 22002
serine/threonine-protein kinase PLK11001
nuclear factor erythroid 2-related factor 2 isoform 12002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
DNA polymerase kappa isoform 11001
lamin isoform A-delta102002
Solute carrier organic anion transporter family member 1A40103
Nuclear receptor subfamily 1 group I member 20011
Solute carrier organic anion transporter family member 1A50002
Rap guanine nucleotide exchange factor 31001
Interferon beta1001
HLA class I histocompatibility antigen, B alpha chain 1001
Transthyretin0103
Cellular tumor antigen p532002
Thyroid hormone receptor alpha0235
Thyroid hormone receptor beta0235
Proliferating cell nuclear antigen0202
Retinoic acid receptor RXR-alpha0022
UDP-glucuronosyltransferase 1A1 0101
Peroxisome proliferator-activated receptor gamma0044
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20002
Solute carrier organic anion transporter family member 1A30002
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Inositol hexakisphosphate kinase 11001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Solute carrier organic anion transporter family member 1B10002
cytochrome P450 2C9, partial1001
glp-1 receptor, partial2002
Solute carrier family 22 member 1 0101
AR protein1001
progesterone receptor1001
glucocorticoid receptor [Homo sapiens]1001
farnesoid X nuclear receptor1001
glucocerebrosidase1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
chromobox protein homolog 11001
geminin1001
peripheral myelin protein 221001
muscleblind-like protein 1 isoform 11001
neuropeptide S receptor isoform A1001
Bile salt export pump0101
Prothrombin0011
Androgen receptor0101
Thyroid hormone receptor beta0101
Adenosine receptor A10202
Sigma non-opioid intracellular receptor 10011
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4A10001
Solute carrier organic anion transporter family member 1C10101
Solute carrier organic anion transporter family member 1B30001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]