Page last updated: 2024-12-05
elemicin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 10248 |
| CHEMBL ID | 458690 |
| CHEBI ID | 4771 |
| SCHEMBL ID | 68542 |
| MeSH ID | M0042628 |
Synonyms (58)
| Synonym |
|---|
| benzene, 5-allyl-1,2,3-trimethoxy- |
| benzene, 1,2,3-trimethoxy-5-(2-propenyl)- |
| ai3-20815 |
| 5-allyl-1,2,3-trimethoxybenzene |
| brn 1912664 |
| nsc 16704 |
| einecs 207-649-0 |
| 1,2,3-trimethoxy-5-(2-propenyl)benzene |
| ccris 6783 |
| 3,4,5-trimethoxyallylbenzene |
| nsc16704 |
| benzene,2,3-trimethoxy-5-(2-propenyl)- |
| nsc-16704 |
| 3,5-trimethoxyallylbenzene |
| elemicin |
| 487-11-6 |
| 1,2,3-trimethoxy-5-prop-2-enylbenzene |
| FT-0652063 |
| chebi:4771 , |
| 5'-metoxy eugenol |
| CHEMBL458690 |
| 4-06-00-07478 (beilstein handbook reference) |
| hsz191akan , |
| unii-hsz191akan |
| 1,2,3-trimethoxy-5-prop-2-enyl-benzene |
| A827594 |
| 5-(prop-2-en-1-yl)-1,2,3-trimethoxybenzene |
| 3-(3,4,5-trimethoxyphenyl)-1-propene |
| 1,2,3-trimethoxy-5-(prop-2-en-1-yl)benzene |
| AKOS015896443 |
| S5120 |
| SCHEMBL68542 |
| 4-allyl-1,2,6-trimethoxybenzene |
| 5-(prop-2-enyl)-1,2,3-trimethoxybenzene |
| 1-allyl-3,4,5-trimethoxybenzene |
| 1-(3,4,5-trimethoxyphenyl)-2-propene |
| 3,4,5-trimethoxyallyl benzene |
| benzene, 1,2,3-trimethoxy-5-(2-propen-1-yl)- |
| 5-allyl-1,2,3-trimethoxy-benzene |
| PS-4970 |
| benzene, 5-(2-propenyl)-1,2,3-trimethoxy |
| BPLQKQKXWHCZSS-UHFFFAOYSA-N |
| elemicine |
| 1,2,3-trimethoxy-5-(2-propenyl)-benzene |
| 1,2,3-trimethoxy-5-allylbenzene |
| mfcd01656688 |
| J-520432 |
| DTXSID60197586 |
| benzene, 1,2,3-trimethoxy-5-(2-propenyl)- (9ci) |
| 1,2,3-trimethoxy-5-[2-propenyl]-benzene |
| 1,2,3-trimethoxy-5-allylbenzene (elemicin) |
| 1,2,3-trimethoxy-5-(2-propenyl)benzene, 9ci |
| 3,4, 5-trimethoxyallylbenzene |
| Q417746 |
| CCG-266643 |
| CS-0030665 |
| HY-N6807 |
| 4-(2-ethyl-benzoimidazol-1-yl)-4-oxo-butyricacid |
Research Excerpts
Overview
Elemicin is a constituent of natural aromatic phenylpropanoids present in many herbs and spices.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Elemicin (Ele) is a constituent of natural alkenylbenzene present in many foods and herbs. " | ( Elemicin exposure induced aberrant lipid metabolism via modulation of gut microbiota in mice. Gu, Z; Ji, M; Li, L; Pei, W; Wu, Q; Zhang, Y; Zhang, Z; Zhu, J, 2022) | 3.61 |
| "Elemicin is a constituent of natural aromatic phenylpropanoids present in many herbs and spices. " | ( Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1. Dai, MY; Gonzalez, FJ; Li, F; Qin, HB; Qu, Y; Wang, YK; Xiao, XR; Yang, XN; Yang, XW; Zhang, T; Zhu, X, 2019) | 2.26 |
Pharmacokinetics
| Excerpt | Reference | Relevance |
|---|---|---|
| "A selective, accurate and sensitive method using gas chromatography-mass spectroscopy (GC-MS) for the simultaneous determination and pharmacokinetic study of β-asarone, α-asarone, elemicin and cis-methyl isoeugenol in rat plasma was developed and validated." | ( GC-MS method for determination and pharmacokinetic study of four phenylpropanoids in rat plasma after oral administration of the essential oil of Acorus tatarinowii Schott rhizomes. Kuang, H; Li, J; Meng, Y; Wang, Q; Wang, Z; Yang, B; Yang, C, 2014) | 0.59 |
Compound-Compound Interactions
| Excerpt | Reference | Relevance |
|---|---|---|
| " In this study, the quality and odor characteristics of five groups of nutmeg samples with different degrees of mildew were analyzed by using the responses of an electronic nose combined with chemical profiling." | ( Detection of Mildewed Nutmeg Internal Quality during Storage Using an Electronic Nose Combined with Chemical Profile Analysis. Cui, Y; Liang, J; Ouyang, S; Wang, Y; Yan, Y; Yang, R; Yao, Y; Yu, S; Zou, H, 2023) | 0.91 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Drug Classes (1)
| Class | Description |
|---|---|
| olefinic compound | Any organic molecular entity that contains at least one C=C bond. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Bioassays (18)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID376040 | Antifungal activity against Microsporum canis C 112 up to 50 ug/mL by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID1541174 | Inhibition of LPS-induced NO production in mouse RAW264.7 cells incubated for 24 hrs in presence of LPS by Griess reagent based assay | 2019 | Journal of natural products, 11-22, Volume: 82, Issue:11 | Lignans from |
| AID376042 | Antifungal activity against Trichophyton mentagrophytes ATCC 9972 up to 50 ug/mL by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376044 | Antifungal activity against Epidermophyton floccosum C 114 up to 50 ug/mL by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376050 | Antifungal activity against Saccharomyces cerevisiae ATCC 9763 by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376046 | Antifungal activity against Trichophyton mentagrophytes ATCC by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376045 | Antifungal activity against Microsporum gypseum C 115 by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID1541175 | Cytotoxicity against mouse RAW264.7 cells assessed as effect on cell viability at 10 uM by CCK-8 assay | 2019 | Journal of natural products, 11-22, Volume: 82, Issue:11 | Lignans from |
| AID376048 | Antifungal activity against Epidermophyton floccosum C 114 by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376041 | Antifungal activity against Microsporum gypseum C 115 up to 50 ug/mL by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376055 | Antifungal activity against Microsporum canis C 112 by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376047 | Antifungal activity against Trichophyton rubrum C 113 by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376051 | Antifungal activity against Cryptococcus neoformans ATCC 32264 by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376052 | Antifungal activity against Aspergillus flavus ATCC 9170 by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376053 | Antifungal activity against Aspergillus fumigatus ATCC 26934 by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376043 | Antifungal activity against Trichophyton rubrum C 113 up to 50 ug/mL by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376054 | Antifungal activity against Aspergillus niger ATCC 9029 by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| AID376049 | Antifungal activity against Candida albicans ATCC 10231 by agar dilution method | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10 | In vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (31)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3 (9.68) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 11 (35.48) | 29.6817 |
| 2010's | 7 (22.58) | 24.3611 |
| 2020's | 7 (22.58) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 44.31
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (44.31) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 1 (3.13%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 31 (96.88%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||