Compounds > 1-o-pentylglycerol
Page last updated: 2024-11-06

1-o-pentylglycerol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1-O-pentylglycerol, also known as 1-pentylglycerol, is a monoglyceride that has been investigated for its potential therapeutic properties. It is a naturally occurring compound found in various plants and animal sources. The compound has been synthesized through various methods, including enzymatic transesterification of glycerol with pentanol. Research suggests that 1-O-pentylglycerol possesses anti-inflammatory, antioxidant, and neuroprotective activities. It is being studied for its potential benefits in treating conditions like inflammation, oxidative stress, and neurodegenerative diseases. The compound's mechanism of action involves modulation of signaling pathways and cellular processes related to inflammation and neuroprotection. 1-O-pentylglycerol's ability to cross the blood-brain barrier makes it a promising candidate for the treatment of neurological disorders.'

1-O-pentylglycerol: an alkylglycerol, increases the transfer of ErPC into the brain [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID90819
CHEMBL ID1988234
SCHEMBL ID11158
MeSH IDM0442266

Synonyms (20)

Synonym
nsc625446
nsc-625446
3-pentoxypropane-1,2-diol
3-(pentyloxy)-1,2-propanediol
NCI60_007850
brn 1739223
1,2-propanediol, 3-pentoxy-
3-pentyloxy-1,2-propanediol
1-o-pentylglycerol
22636-32-4
1,2-propanediol, 3-(pentyloxy)-
SCHEMBL11158
monopentyl glyceryl ether
3(pentyloxy)-1,2-propanediol
FQJXITFHANYMET-UHFFFAOYSA-N
amyl glyceryl ether
CHEMBL1988234
DTXSID40945300
3-(pentyloxy)propane-1,2-diol
3-pentyloxypropane-1,2-diol
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.43

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.43 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.37 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.43)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
glycerol
Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.		8.2860alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
phosphorylcholine
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.. phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.		2.0110phosphocholinesallergen;
epitope;
hapten;
human metabolite;
mouse metabolite
mannitol
[no description available]		2.0110mannitolallergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent
fluorescein
Fluorescein: A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium such as the aqueous humor.. fluorescein (lactone form) : A xanthene dye that is highly fluorescent, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy.		2.01102-benzofurans;
gamma-lactone;
organic heteropentacyclic compound;
oxaspiro compound;
polyphenol;
xanthene dye		fluorescent dye;
radioopaque medium
methotrexate
[no description available]		2.4220dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
bradykinin
[no description available]		2.0110oligopeptidehuman blood serum metabolite;
vasodilator agent
erucylphosphocholine
erucylphosphocholine: structure given in first source		2.0110
ConditionIndicatedRelationship StrengthStudiesTrials
Benign Neoplasms, Brain
[description not available]		02.4220
Glial Cell Tumors
[description not available]		02.4220
Brain Neoplasms
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.		02.4220
Glioma
Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)		02.4220