| Assay ID | Title | Year | Journal | Article |
|---|
| AID538900 | Displacement of [3H]Haloperidol from Sigma1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1378103 | n-Octanol-buffer distribution coefficient, log D of the compound at pH 7.4 by mass spectrometry based shake flask method | 2017 | European journal of medicinal chemistry, Sep-29, Volume: 138 | Deconstruction - reconstruction approach to analyze the essential structural elements of tetrahydro-3-benzazepine-based antagonists of GluN2B subunit containing NMDA receptors. |
| AID538902 | Displacement of [3H]-SR-140333 from tachykinin NK1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538906 | Displacement of [3H]-Ifenprodil from NMDA receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538887 | Displacement of [3H]N-Methyl-scopolamine from muscarinic M3 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538926 | Displacement of [125I]-IL-2 from interleukin IL-2 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538759 | Displacement of [3H](+)-pentazocine from sigma1 receptor guinea pig brain after 180 mins scintillation counting | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538797 | Displacement of [3H]-TCP from NMDA phencyclidine receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538791 | Displacement of [3H]Flunitrazepam from benzodiazepine central/GABAA receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538960 | Displacement of radiolabeled ZIPtide from PHKG2 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538959 | Displacement of radiolabeled PARK substrate peptide from MAPKAPK5 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538778 | Displacement of [125I]-Cyanopindolol from adrenergic alpha1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1690207 | Binding affinity to Sigma 2 receptor (unknown origin) | | | |
| AID538788 | Displacement of [125I]-EGF from epidermal growth factor receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538893 | Displacement of [3H]Diprenorphine from mu opioid receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538760 | Displacement of [3H]di-o-tolylguanidine from sigma2 receptor rat liver membranes after 180 mins scintillation counting | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538753 | Antagonist activity at human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells assessed as inhibition of (S)-glutamate/glycine-stimulated excitotoxicity treated 30 mins before (S)-glutamate/glycine challenge measured after 4 hrs by LDH rele | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538938 | Displacement of radiolabeled kynuramine from MAO-A at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538910 | Displacement of radiolabeled Ac-YVAD-AMC from CASP1 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538781 | Displacement of [3H]-Bradykinin from bradykinin B2 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1369086 | Displacement of [3H]-(+)-Pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysis | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2
| 2-Methyltetrahydro-3-benzazepin-1-ols - The missing link in SAR of GluN2B selective NMDA receptor antagonists. |
| AID538762 | Selectivity ratio of Ki for human recombinant NR1a/NR2B receptor to Ki for guinea pig sigma1 receptor | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538773 | Displacement of [125I]-AB-MECA from adenosine A3 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538755 | Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation counting | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538897 | Displacement of [35S] ATP-alpha-S from purinergic P2Y receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538920 | Displacement of [125I]-MIP-1-beta from chemokine CCR5 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538795 | Displacement of [3H]-CGP-39653 from NMDA receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538777 | Displacement of [3H]-MK-912 from adrenergic alpha2A receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538927 | Displacement of [125I]-Leptin from leptin receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538918 | Displacement of [125I]-(Tyr4) Bombesin from bombesin BB2 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1369084 | Displacement of [3H]-DTG from sigma 2 receptor in rat liver membranes after 120 mins by scintillation counting analysis | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2
| 2-Methyltetrahydro-3-benzazepin-1-ols - The missing link in SAR of GluN2B selective NMDA receptor antagonists. |
| AID538937 | Displacement of radiolabeled arachidonic acid from COX1 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538968 | Displacement of radiolabeled Poly(Glu:Tyr) from TEK at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538907 | Displacement of [3H]-DTG from sigma receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538954 | Displacement of radiolabeled Autocamtide-2 from CAMK2D at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538941 | Displacement of [3H]-L-Argenine from nNOS at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538924 | Displacement of [3H]-Quisqulic acid from mGlu5 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538896 | Displacement of [3H]alpha,5-Methylene-ATP from purinergic P2X receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538935 | Displacement of radiolabeled ATP from Na+/K+ ATPase in pig heart at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1690206 | Binding affinity to Sigma 1 receptor (unknown origin) | | | |
| AID538944 | Displacement of radiolabeled N-alpha-Z-D-Arg-Gly-Arg-pNA from factor 10a at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538758 | Displacement of [3H]-(+)-MK 801 from NMDA receptor phencyclidine binding site in pig brain cortex after 150 mins by scintillation counting | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538764 | Half life in rat liver microsomes | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538939 | Displacement of radiolabeled kynuramine from MAO-B at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538936 | Displacement of radiolabeled L-[Methyl-14C] from CPT1 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538801 | Displacement of [3H]-Idazoxan from imidazoline I2, Central receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538899 | Displacement of [3H]-GR-65630 from 5-HT3 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538962 | Displacement of radiolabeled Histone from PRKCE at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538775 | Displacement of [3H]-Prazosin from adrenergic Alpha-1B receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538790 | Displacement of [3H]-Muscimol from agonist site of GABAA receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1597428 | Selectivity ratio of Ki for sigma1 receptor in guinea pig brain cortex membranes to ratio of Ki for GluN2B/GluN1a (unknown origin) expressed in mouse L(tk-) cell membranes | | | |
| AID538912 | Displacement of radiolabeled Ac-IETD-AMC from CASP8 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538946 | Displacement of radiolabeled MOCAc-Ala-Pro-Ala-Lys-Phe-Phe-Arg-Leu-Lys(Dnp)-NH2 from pepsin at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538913 | Displacement of radiolabeled ATF2 from MAPK8 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538966 | Displacement of radiolabeled Poly(Glu:Tyr) from FGFR2 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538768 | Analgesic activity in ip dosed mouse assessed as decrease in von Frey filament-induced neuropathic pain | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538931 | Displacement of [3H]Progesterone from progesterone PR-B receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538794 | Displacement of [3H]-Kainic acid from kainate receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538885 | Displacement of [3H]N-Methyl-scopolamine from muscarinic M1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538919 | Displacement of [125I]-TARC from chemokine CCR4 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538898 | Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538892 | Displacement of [3H]Diprenorphine from kappa opioid receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538798 | Displacement of [3H]-Pyrilamine from histamine H1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538793 | Displacement of [3H]Dexamethasone from glucocorticoid receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538932 | Displacement of [125I]-Triiodothyronine from thyroid hormone receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538925 | Displacement of [125I]-Insulin from insulin receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538956 | Displacement of radiolabeled Axl-tide peptide from DMPK at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538965 | Displacement of radiolabeled Poly(Glu:Tyr) from FGFR1 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538958 | Displacement of radiolabeled IKKtide from IKK-1 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1462756 | Displacement of [3H]-di-o-tolylguanidine from sigma 2 receptor in rat liver membranes after 120 mins by scintillation counting analysis | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| Replacement of benzylic hydroxy group by vinyl or hydroxymethyl moiety at the 3-benzazepine scaffold retaining GluN2B affinity. |
| AID538782 | Displacement of [3H]-SCH-23390 from dopamine D1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538957 | Displacement of radiolabeled Myelin basic protein from HIPK2 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538769 | Analgesic activity in mouse assessed as decrease in von Frey filament-induced neuropathic pain at 30 mg/kg, ip | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538955 | Displacement of radiolabeled Autocamtide-2 from CAMK4 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538776 | Displacement of [3H]-Prazosin from adrenergic Alpha-1D receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1272498 | Binding affinity to sigma-2 receptor (unknown origin) by radioligand displacement assay | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3
| Role of the phenolic OH moiety of GluN2B-selective NMDA antagonists with 3-benzazepine scaffold. |
| AID538780 | Displacement of [3H](Des-Arg10)-Kallidin from bradykinin B1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1462755 | Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| Replacement of benzylic hydroxy group by vinyl or hydroxymethyl moiety at the 3-benzazepine scaffold retaining GluN2B affinity. |
| AID1369085 | Displacement of [3H]-ifenprodil from recombinant human GluN1a/GluN2B expressed in L(tk-) cell membranes after 120 mins by scintillation counting analysis | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2
| 2-Methyltetrahydro-3-benzazepin-1-ols - The missing link in SAR of GluN2B selective NMDA receptor antagonists. |
| AID538787 | Displacement of [125I]-Endothelin-1 from ETB receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538933 | Displacement of [125I]-TGF-beta from TGF-beta receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1462752 | Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation counting method | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| Replacement of benzylic hydroxy group by vinyl or hydroxymethyl moiety at the 3-benzazepine scaffold retaining GluN2B affinity. |
| AID538967 | Displacement of radiolabeled Histone H1 from insulin receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538894 | Displacement of [3H]-PDBu from phorbol ester site of PKC at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538895 | Displacement of [3H]-PAF from platelet activating factor receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538757 | Displacement of [3H]-Ifenprodil from polyamine transporter at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538770 | Analgesic activity in mouse assessed as decrease in von Frey filament-induced neuropathic pain at 10 mg/kg, ip | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538888 | Displacement of [125I]-Peptide YY from neuropeptide Y1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538943 | Displacement of radiolabeled N-CH3-SO2-D-Phe-Gly-Arg-pNA from factor 7a at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538756 | Analgesic activity in mouse assessed reduction formalin-induced acute pain at 10 to 100 mg/kg, ip administered 30 mins before formalin challenge measured after 10 to 35 mins | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538774 | Displacement of [3H]-Prazosin from adrenergic alpha1A receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538763 | Half life in mouse liver microsomes | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538786 | Displacement of [125I]-Endothelin-1 from ETA receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538950 | Displacement of [3H]cAMP from PDE3 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1272497 | Binding affinity to sigma-1 receptor (unknown origin) by radioligand displacement assay | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3
| Role of the phenolic OH moiety of GluN2B-selective NMDA antagonists with 3-benzazepine scaffold. |
| AID538970 | Displacement of radiolabeled DiFMUP from ACP1 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538948 | Displacement of radiolabeled N-alpha-Z-D-Arg-Gly-Arg-pNA from tissue plasminogen activator at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538904 | Displacement of [3H]prazosin from adrenergic alpha1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538903 | Displacement of [3H]-Mibolerone from testosterone receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538802 | Displacement of [125I]-Interleukin-1-alpha from IL-1 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538923 | Displacement of [3H]-AMPA from AMPA receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1462754 | Displacement of [3H]-(+)-MK-801 from PCP binding site of NMDA receptor in pig brain cortex at 1 uM | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| Replacement of benzylic hydroxy group by vinyl or hydroxymethyl moiety at the 3-benzazepine scaffold retaining GluN2B affinity. |
| AID538969 | Displacement of radiolabeled Poly(Glu:Tyr) from ZA70 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID539062 | Displacement of [3H]-Ifenprodil from glutamate receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1597395 | Displacement of [3H] ifenprodil from GluN2B/GluN1a (unknown origin) expressed in mouse L(tk-) cell membranes incubated for 120 mins by scintillation counting method | | | |
| AID538947 | Displacement of radiolabeled Z-Gyl-Pro-Arg-AMC from thrombin at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538922 | Displacement of [125I]-IL-8 from chemokine CXCR2 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538784 | Displacement of [3H Spiperone from dopamine D3 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538942 | Displacement of radiolabeled MOCAc-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2 from cathepsin D at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538908 | Displacement of radiolabeled arachidonic acid from Cox2 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538971 | Displacement of radiolabeled scopoletin from UGT1A1 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1272496 | Displacement of [3H]ifenprodil from recombinant human GluN1a/GluN2B expressed in L(tk-)cells | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3
| Role of the phenolic OH moiety of GluN2B-selective NMDA antagonists with 3-benzazepine scaffold. |
| AID538799 | Displacement of [125I]-Aminopotentidine from histamine H2 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538934 | Displacement of [125I]-TNF-alpha from TNF receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538945 | Displacement of radiolabeled glutaryl-Ala-Ala-Phe-4-methoxy-2-naphthylamide from neutral endo-peptidase at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538929 | Displacement of [3H]-PAF from PAF receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538789 | Displacement of [3H]-Estradiol from ERalpha receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538886 | Displacement of [3H]N-Methyl-scopolamine from muscarinic M2 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538783 | Displacement of [3H]-Spiperone from dopamine D2 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538796 | Displacement of [3H]-MDL-105519 from glycine recognition site of NMDA receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538952 | Displacement of [3H]-cGMP from PDE6 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538891 | Displacement of [3H]Naltrindole from delta opioid receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538766 | Toxicity in mouse assessed as unusual reactions at 1 to 100 mg/kg, ip after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538915 | Displacement of [125I]-C5a Anaphylatoxin from anaphylatoxin C5a at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538772 | Displacement of [3H]-CGS-21680 from adenosine A2A receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538765 | Half life in human liver microsomes | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1369087 | Displacement of [3H]-(+)-MK-801 from PCP binding site of NMDA receptor in pig brain cortex membranes at 10 uM after 150 mins by solid scintillation counting relative to control | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2
| 2-Methyltetrahydro-3-benzazepin-1-ols - The missing link in SAR of GluN2B selective NMDA receptor antagonists. |
| AID538963 | Displacement of radiolabeled ZIPtide from STK17A at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538767 | Toxicity in mouse assessed as diarrhea at 100 mg/kg, ip after 30 mins | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1272500 | Binding affinity to PCP binding site of NMDA receptor (unknown origin) at 10 uM by radioligand displacement assay | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3
| Role of the phenolic OH moiety of GluN2B-selective NMDA antagonists with 3-benzazepine scaffold. |
| AID538889 | Displacement of [125I]-Peptide YY from neuropeptide Y2 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538953 | Displacement of radiolabeled Suc-LLVY-AMC from proteasome at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538928 | Displacement of [125I]-NDP-alpha-MSH from melanocortin MC3 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538916 | Displacement of [125I]-ANF from atrial natriuretic factor receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538890 | Displacement of [125I]-epibatidine from nicotinic acetylcholine receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538800 | Displacement of [3H]R(-)-alpha-Methylhistamine from histamine H3 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538909 | Displacement of radiolabeled casein-FITC from CAN1 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538917 | Displacement of [125I]-(Tyr4)-Bombesin from bombesin BB1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538914 | Displacement of [3H]D-Aldosterone from aldosterone receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538949 | Displacement of radiolabeled Z-Gly-Pro-Arg-AMC from trypsin at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538911 | Displacement of radiolabeled Ac-DEVD-AMC from CASP3 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538951 | Displacement of [3H]-cAMP from PDE4 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538901 | Displacement of [3H]-Ifenprodil from sigma2 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1597396 | Displacement of [3H]-(+)-MK-801 from NMDA PCP binding site in pig brain cortex membrane at 1 uM incubated for 120 mins by scintillation counting method relative to control | | | |
| AID538940 | Displacement of [3H]-L-Argenine + L-Argenine from eNOS at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538964 | Displacement of radiolabeled CHKtide from TSSK2 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538803 | Displacement of [3H]Leukotriene D4 Leukotriene from cysteinyl CysLT1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538930 | Displacement of [3H]-Astemizole from human ERG | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538754 | Antagonist activity at human recombinant NR1-1a/NR2A receptor expressed in mouse L12-G10 cells assessed as inhibition of (S)-glutamate/glycine-stimulated excitotoxicity at 10 uM treated 30 mins before (S)-glutamate/glycine challenge measured after 4 hrs b | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538961 | Displacement of radiolabeled MAPKAPK from PKD2 at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID1690205 | Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by scintillation counting method | | | |
| AID538792 | Displacement of [3H]-CGP-54626 from GABAB receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538771 | Displacement of [3H]-DPCPX from adenosine A1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538921 | Displacement of [125I]-Fractalkine from chemokine CX3CR1 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538779 | Displacement of [3H]-CGP-12177 from adrenergic alpha2 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538785 | Displacement of [3H]-Spiperone from dopamine D4.2 receptor at 1 to 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| AID538905 | Displacement of [125I]-CGRP from CGRP1 at 3 uM | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22
| Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |