Page last updated: 2024-11-12

3-oxetanone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID15024254
CHEMBL ID4779660
MeSH IDM0581492

Synonyms (30)

Synonym
6704-31-0
oxetan-3-one
A24178
AKOS005259076
3-oxetanone ,
c3h4o2
1,3-epoxy-2-propanone
FT-0648683
AM20020042
PB20352
CS-M1912
mfcd09263255
oxetane-3-one
ROADCYAOHVSOLQ-UHFFFAOYSA-N
3-oxooxetane
oxetan-3-on
STR08949
DTXSID80567101
J-512993
SY003915
BCP05482
O0467
Q753254
EN300-69922
bdbm50551697
chembl4779660 ,
2-propanone, 1,3-epoxy-
tgb3b74hzp ,
unii-tgb3b74hzp
HY-76440
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (1)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Epoxide hydrolase 1 Homo sapiens (human)IC50 (µMol)100.00000.04002.98007.0000AID1691497
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (6)

Processvia Protein(s)Taxonomy
xenobiotic metabolic processEpoxide hydrolase 1 Homo sapiens (human)
response to toxic substanceEpoxide hydrolase 1 Homo sapiens (human)
response to organic cyclic compoundEpoxide hydrolase 1 Homo sapiens (human)
arachidonic acid metabolic processEpoxide hydrolase 1 Homo sapiens (human)
catabolic processEpoxide hydrolase 1 Homo sapiens (human)
epoxide metabolic processEpoxide hydrolase 1 Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (4)

Processvia Protein(s)Taxonomy
epoxide hydrolase activityEpoxide hydrolase 1 Homo sapiens (human)
protein bindingEpoxide hydrolase 1 Homo sapiens (human)
oxysterol bindingEpoxide hydrolase 1 Homo sapiens (human)
cis-stilbene-oxide hydrolase activityEpoxide hydrolase 1 Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (1)

Processvia Protein(s)Taxonomy
endoplasmic reticulum membraneEpoxide hydrolase 1 Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1691497Inhibition of human mEH using CMNGC as substrate preincubated for 5 mins followed by substrate addition and measured at 30 secs interval for 10 mins by fluorescence assay2020European journal of medicinal chemistry, May-01, Volume: 193Development of potent inhibitors of the human microsomal epoxide hydrolase.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 29.21

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index29.21 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index32.99 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (29.21)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]