Page last updated: 2024-10-06

Transcriptional Regulation by TP53

Proteins (218)

ProteinSynonymsTaxonomy
DNA topoisomerase 2-binding protein 1DNA topoisomerase II-beta-binding protein 1; TopBP1; DNA topoisomerase II-binding protein 1Homo sapiens (human)
PR domain zinc finger protein 1EC 2.1.1.-; BLIMP-1; Beta-interferon gene positive regulatory domain I-binding factor; PR domain-containing protein 1; Positive regulatory domain I-binding factor 1; PRDI-BF1; PRDI-binding factor 1Homo sapiens (human)
Rab proteins geranylgeranyltransferase component A 1Choroideremia protein; Rab escort protein 1; REP-1; TCD proteinHomo sapiens (human)
14-3-3 protein etaProtein AS1Homo sapiens (human)
Phorbol-12-myristate-13-acetate-induced protein 1PMA-induced protein 1; Immediate-early-response protein APR; Protein NoxaHomo sapiens (human)
Histone acetyltransferase KAT6AEC 2.3.1.48; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3; MYST-3; Monocytic leukemia zinc finger protein; Runt-related transcription factor-binding protein 2; Zinc finger protein 220Homo sapiens (human)
Target of rapamycin complex 2 subunit MAPKAP1TORC2 subunit MAPKAP1; Mitogen-activated protein kinase 2-associated protein 1; Stress-activated map kinase-interacting protein 1; SAPK-interacting protein 1; mSIN1Homo sapiens (human)
NLR family CARD domain-containing protein 4CARD, LRR, and NACHT-containing protein; Clan protein; Caspase recruitment domain-containing protein 12; Ice protease-activating factor; IpafHomo sapiens (human)
Glutaminase liver isoform, mitochondrialGLS; EC 3.5.1.2; L-glutaminase; L-glutamine amidohydrolaseHomo sapiens (human)
Serine/threonine-protein kinase Sgk1EC 2.7.11.1; Serum/glucocorticoid-regulated kinase 1Homo sapiens (human)
Serine/threonine-protein kinase Chk1EC 2.7.11.1; CHK1 checkpoint homolog; Cell cycle checkpoint kinase; Checkpoint kinase-1Homo sapiens (human)
Aurora kinase AEC 2.7.11.1; Aurora 2; Aurora/IPL1-related kinase 1; ARK-1; Aurora-related kinase 1; hARK1; Breast tumor-amplified kinase; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; Serine/threonine-protein kinase aurora-AHomo sapiens (human)
3-phosphoinositide-dependent protein kinase 1hPDK1; EC 2.7.11.1Homo sapiens (human)
NUAK family SNF1-like kinase 1EC 2.7.11.1; AMPK-related protein kinase 5; ARK5; Omphalocele kinase 1Homo sapiens (human)
Cellular tumor antigen p53Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53Homo sapiens (human)
Cyclin-dependent kinase 1CDK1; EC 2.7.11.22; EC 2.7.11.23; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinaseHomo sapiens (human)
G2/mitotic-specific cyclin-B1Homo sapiens (human)
Cyclin-dependent kinase 2EC 2.7.11.22; Cell division protein kinase 2; p33 protein kinaseHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 6MAP kinase kinase 6; MAPKK 6; EC 2.7.12.2; MAPK/ERK kinase 6; MEK 6; Stress-activated protein kinase kinase 3; SAPK kinase 3; SAPKK-3; SAPKK3Homo sapiens (human)
Phosphatidylinositol 5-phosphate 4-kinase type-2 betaEC 2.7.1.149; 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; Diphosphoinositide kinase 2-beta; Phosphatidylinositol 5-phosphate 4-kinase type II beta; PI(5)P 4-kinase type II beta; PIP4KII-beta; PtdIns(5)P-4-kinase isoform 2-betaHomo sapiens (human)
Cyclin-dependent-like kinase 5 EC 2.7.11.1; Cell division protein kinase 5; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunitHomo sapiens (human)
Histone deacetylase 1HD1; EC 3.5.1.98Homo sapiens (human)
Homeodomain-interacting protein kinase 1EC 2.7.11.1; Nuclear body-associated kinase 2Homo sapiens (human)
MAP kinase-activated protein kinase 5MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5; EC 2.7.11.1; p38-regulated/activated protein kinase; PRAKHomo sapiens (human)
Dual specificity tyrosine-phosphorylation-regulated kinase 2EC 2.7.12.1Homo sapiens (human)
Histone deacetylase 2HD2; EC 3.5.1.98Homo sapiens (human)
Aurora kinase BEC 2.7.11.1; Aurora 1; Aurora- and IPL1-like midbody-associated protein 1; AIM-1; Aurora/IPL1-related kinase 2; ARK-2; Aurora-related kinase 2; STK-1; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase aHomo sapiens (human)
General transcription and DNA repair factor IIH helicase subunit XPBTFIIH subunit XPB; EC 3.6.4.12; Basic transcription factor 2 89 kDa subunit; BTF2 p89; DNA excision repair protein ERCC-3; DNA repair protein complementing XP-B cells; TFIIH basal transcription factor complex 89 kDa subunit; TFIIH 89 kDa subunit; TFIIH p8Homo sapiens (human)
Transcription initiation factor TFIID subunit 11TFIID subunit p30-beta; Transcription initiation factor TFIID 28 kDa subunit; TAF(II)28; TAFII-28; TAFII28Homo sapiens (human)
Transcription initiation factor TFIID subunit 3140 kDa TATA box-binding protein-associated factor; TBP-associated factor 3; Transcription initiation factor TFIID 140 kDa subunit; TAF(II)140; TAF140; TAFII-140; TAFII140Homo sapiens (human)
Cytochrome c oxidase subunit 1EC 7.1.1.9; Cytochrome c oxidase polypeptide IHomo sapiens (human)
Protein Mdm4Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4Homo sapiens (human)
Serine/threonine-protein kinase Chk2EC 2.7.11.1; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2Homo sapiens (human)
Cytochrome c oxidase subunit 2EC 7.1.1.9; Cytochrome c oxidase polypeptide IIHomo sapiens (human)
Transcription factor AP-1Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39Homo sapiens (human)
Caspase-1CASP-1; EC 3.4.22.36; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45Homo sapiens (human)
M-phase inducer phosphatase 3EC 3.1.3.48; Dual specificity phosphatase Cdc25CHomo sapiens (human)
Serine/threonine-protein kinase mTOREC 2.7.11.1; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1Homo sapiens (human)
Caspase-2CASP-2; EC 3.4.22.55; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1Homo sapiens (human)
Caspase-6CASP-6; EC 3.4.22.59; Apoptotic protease Mch-2Homo sapiens (human)
BH3-interacting domain death agonistp22 BID; BIDHomo sapiens (human)
Casein kinase II subunit betaCK II beta; Phosvitin; Protein G5aHomo sapiens (human)
E3 ubiquitin-protein ligase Mdm2EC 2.3.2.27; Double minute 2 protein; Hdm2; Oncoprotein Mdm2; RING-type E3 ubiquitin transferase Mdm2; p53-binding protein Mdm2Homo sapiens (human)
Apoptosis regulator BAX Bcl-2-like protein 4; Bcl2-L-4Homo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
Cyclin-dependent kinase 13EC 2.7.11.22; EC 2.7.11.23; CDC2-related protein kinase 5; Cell division cycle 2-like protein kinase 5; Cell division protein kinase 13; hCDK13; Cholinesterase-related cell division controllerHomo sapiens (human)
Cyclin-dependent kinase 5 activator 1CDK5 activator 1; Cyclin-dependent kinase 5 regulatory subunit 1; TPKII regulatory subunitHomo sapiens (human)
Histone-lysine N-methyltransferase EHMT2EC 2.1.1.-; Euchromatic histone-lysine N-methyltransferase 2; HLA-B-associated transcript 8; Histone H3-K9 methyltransferase 3; H3-K9-HMTase 3; Lysine N-methyltransferase 1C; Protein G9aHomo sapiens (human)
Homeodomain-interacting protein kinase 2hHIPk2; EC 2.7.11.1Homo sapiens (human)
Serine/threonine-protein kinase PLK3EC 2.7.11.21; Cytokine-inducible serine/threonine-protein kinase; FGF-inducible kinase; Polo-like kinase 3; PLK-3; Proliferation-related kinaseHomo sapiens (human)
Histone-lysine N-methyltransferase EHMT1EC 2.1.1.-; Euchromatic histone-lysine N-methyltransferase 1; Eu-HMTase1; G9a-like protein 1; GLP; GLP1; Histone H3-K9 methyltransferase 5; H3-K9-HMTase 5; Lysine N-methyltransferase 1DHomo sapiens (human)
B-cell lymphoma 6 proteinBCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51Homo sapiens (human)
CCR4-NOT transcription complex subunit 1CCR4-associated factor 1; Negative regulator of transcription subunit 1 homolog; NOT1H; hNOT1Homo sapiens (human)
DNA mismatch repair protein Msh2hMSH2; MutS protein homolog 2Homo sapiens (human)
Glucose-6-phosphate isomeraseGPI; EC 5.3.1.9; Autocrine motility factor; AMF; Neuroleukin; NLK; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI; Sperm antigen 36; SA-36Homo sapiens (human)
14-3-3 protein theta14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1Homo sapiens (human)
Replication factor C subunit 5Activator 1 36 kDa subunit; A1 36 kDa subunit; Activator 1 subunit 5; Replication factor C 36 kDa subunit; RF-C 36 kDa subunit; RFC36Homo sapiens (human)
CCR4-NOT transcription complex subunit 9Cell differentiation protein RQCD1 homolog; Rcd-1Homo sapiens (human)
CCR4-NOT transcription complex subunit 10Homo sapiens (human)
Insulin-like growth factor-binding protein 3IBP-3; IGF-binding protein 3; IGFBP-3Homo sapiens (human)
Peroxiredoxin-1EC 1.11.1.24; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; Thioredoxin-dependent peroxiredoxin 1Homo sapiens (human)
Geranylgeranyl transferase type-2 subunit alphaEC 2.5.1.60; Geranylgeranyl transferase type II subunit alpha; Rab geranyl-geranyltransferase subunit alpha; Rab GG transferase alpha; Rab GGTase alpha; Rab geranylgeranyltransferase subunit alphaHomo sapiens (human)
Bcl-2-binding component 3, isoforms 1/2JFY-1; p53 up-regulated modulator of apoptosisHomo sapiens (human)
Targeting protein for Xklp2Differentially expressed in cancerous and non-cancerous lung cells 2; DIL-2; Hepatocellular carcinoma-associated antigen 519; Hepatocellular carcinoma-associated antigen 90; Protein fls353; Restricted expression proliferation-associated protein 100; p100Homo sapiens (human)
Cytochrome c oxidase subunit NDUFA4Complex I-MLRQ; CI-MLRQ; NADH-ubiquinone oxidoreductase MLRQ subunitHomo sapiens (human)
14-3-3 protein sigmaEpithelial cell marker protein 1; StratifinHomo sapiens (human)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENEC 3.1.3.16; EC 3.1.3.48; EC 3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homologHomo sapiens (human)
Cytochrome cHomo sapiens (human)
Tumor necrosis factor receptor superfamily member 6Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptorHomo sapiens (human)
Geranylgeranyl transferase type-2 subunit betaEC 2.5.1.60; Geranylgeranyl transferase type II subunit beta; GGTase-II-beta; Rab geranyl-geranyltransferase subunit beta; Rab GG transferase beta; Rab GGTase beta; Rab geranylgeranyltransferase subunit beta; Type II protein geranyl-geranyltransferase subHomo sapiens (human)
Cyclin-G1Cyclin-GHomo sapiens (human)
Apoptotic protease-activating factor 1APAF-1Homo sapiens (human)
Protein arginine N-methyltransferase 5PRMT5; EC 2.1.1.320; 72 kDa ICln-binding protein; Histone-arginine N-methyltransferase PRMT5; Jak-binding protein 1; Shk1 kinase-binding protein 1 homolog; SKB1 homolog; SKB1HsHomo sapiens (human)
Baculoviral IAP repeat-containing protein 5Apoptosis inhibitor 4; Apoptosis inhibitor survivinHomo sapiens (human)
Ubiquitin carboxyl-terminal hydrolase 2EC 3.4.19.12; 41 kDa ubiquitin-specific protease; Deubiquitinating enzyme 2; Ubiquitin thioesterase 2; Ubiquitin-specific-processing protease 2Homo sapiens (human)
Cyclin-KHomo sapiens (human)
Glutaminase kidney isoform, mitochondrialGLS; EC 3.5.1.2; K-glutaminase; L-glutamine amidohydrolaseHomo sapiens (human)
NucleophosminNPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; NumatrinHomo sapiens (human)
ThioredoxinTrx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASPHomo sapiens (human)
Glucose-6-phosphate 1-dehydrogenaseG6PD; EC 1.1.1.49Homo sapiens (human)
Proliferating cell nuclear antigenPCNA; CyclinHomo sapiens (human)
Cyclin-dependent kinase inhibitor 1CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21Homo sapiens (human)
Phosphatidylinositol 5-phosphate 4-kinase type-2 alphaEC 2.7.1.149; 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; Diphosphoinositide kinase 2-alpha; PIP5KIII; Phosphatidylinositol 5-Phosphate 4-Kinase; PI5P4Kalpha; Phosphatidylinositol 5-phosphate 4-kinase type II alpha; PI(5)P 4-kinase type II alpha;Homo sapiens (human)
14-3-3 protein gammaProtein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
Transcription factor E2F1E2F-1; PBR3; Retinoblastoma-associated protein 1; RBAP-1; Retinoblastoma-binding protein 3; RBBP-3; pRB-binding protein E2F-1Homo sapiens (human)
Histone-binding protein RBBP4Chromatin assembly factor 1 subunit C; CAF-1 subunit C; Chromatin assembly factor I p48 subunit; CAF-I 48 kDa subunit; CAF-I p48; Nucleosome-remodeling factor subunit RBAP48; Retinoblastoma-binding protein 4; RBBP-4; Retinoblastoma-binding protein p48Homo sapiens (human)
Serine-protein kinase ATMEC 2.7.11.1; Ataxia telangiectasia mutated; A-T mutatedHomo sapiens (human)
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1EC 5.2.1.8; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; Rotamase Pin1Homo sapiens (human)
Serine/threonine-protein kinase STK11EC 2.7.11.1; Liver kinase B1; LKB1; hLKB1; Renal carcinoma antigen NY-REN-19Homo sapiens (human)
Histone-binding protein RBBP7Histone acetyltransferase type B subunit 2; Nucleosome-remodeling factor subunit RBAP46; Retinoblastoma-binding protein 7; RBBP-7; Retinoblastoma-binding protein p46Homo sapiens (human)
Thioredoxin reductase 1, cytoplasmicTR; EC 1.8.1.9; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1Homo sapiens (human)
Rapamycin-insensitive companion of mTORAVO3 homolog; hAVO3Homo sapiens (human)
Histone-arginine methyltransferase CARM1EC 2.1.1.319; Coactivator-associated arginine methyltransferase 1; Protein arginine N-methyltransferase 4Homo sapiens (human)
Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaEC 2.7.1.149; Phosphatidylinositol 5-phosphate 4-kinase type II gamma; PI(5)P 4-kinase type II gamma; PIP4KII-gammaHomo sapiens (human)
CREB-binding proteinHistone lysine acetyltransferase CREBBP; 2.3.1.48; Protein-lysine acetyltransferase CREBBP; 2.3.1.-Homo sapiens (human)
Caspase-10CASP-10; EC 3.4.22.63; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4Homo sapiens (human)
Ubiquitin carboxyl-terminal hydrolase 7EC 3.4.19.12; Deubiquitinating enzyme 7; Herpesvirus-associated ubiquitin-specific protease; Ubiquitin thioesterase 7; Ubiquitin-specific-processing protease 7Homo sapiens (human)
EKC/KEOPS complex subunit TP53RKEC 3.6.-.-; Atypical serine/threonine protein kinase TP53RK; Nori-2; TP53-regulating kinase; 2.7.11.1; p53-related protein kinaseHomo sapiens (human)
Protein arginine N-methyltransferase 1EC 2.1.1.319; Histone-arginine N-methyltransferase PRMT1; Interferon receptor 1-bound protein 4Homo sapiens (human)
Target of rapamycin complex subunit LST8TORC subunit LST8; G protein beta subunit-like; Gable; Protein GbetaL; Mammalian lethal with SEC13 protein 8; mLST8Homo sapiens (human)
N-lysine methyltransferase SMYD2EC 2.1.1.-; HSKM-B; Histone methyltransferase SMYD2; 2.1.1.354; Lysine N-methyltransferase 3C; SET and MYND domain-containing protein 2Homo sapiens (human)
Cyclin-dependent kinase 12EC 2.7.11.22; EC 2.7.11.23; Cdc2-related kinase, arginine/serine-rich; CrkRS; Cell division cycle 2-related protein kinase 7; CDC2-related protein kinase 7; Cell division protein kinase 12; hCDK12Homo sapiens (human)
Serine/threonine-protein kinase PLK2EC 2.7.11.21; Polo-like kinase 2; PLK-2; hPlk2; Serine/threonine-protein kinase SNK; hSNK; Serum-inducible kinaseHomo sapiens (human)
Lethal(3)malignant brain tumor-like protein 1H-l(3)mbt; H-l(3)mbt protein; L(3)mbt-like; L(3)mbt protein homolog; L3MBTL1Homo sapiens (human)
General transcription and DNA repair factor IIH helicase subunit XPDTFIIH subunit XPD; EC 3.6.4.12; Basic transcription factor 2 80 kDa subunit; BTF2 p80; CXPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; TFIIH basal transcription factor complex 80 kDa subunit; TFIIH 80 kDa subunit; TFHomo sapiens (human)
14-3-3 protein beta/alphaProtein 1054; Protein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
Cyclic AMP-dependent transcription factor ATF-2cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; HB16; cAMP response element-binding protein CRE-BP1Homo sapiens (human)
DNA mismatch repair protein Mlh1 MutL protein homolog 1Homo sapiens (human)
Mismatch repair endonuclease PMS2EC 3.1.-.-; DNA mismatch repair protein PMS2; PMS1 protein homolog 2Homo sapiens (human)
Tumor protein 63p63; Chronic ulcerative stomatitis protein; CUSP; Keratinocyte transcription factor KET; Transformation-related protein 63; TP63; Tumor protein p73-like; p73L; p40; p51Homo sapiens (human)
Tetratricopeptide repeat protein 5TPR repeat protein 5; Stress-responsive activator of p300; StrapHomo sapiens (human)
Cell cycle checkpoint protein RAD1hRAD1; EC 3.1.11.2; DNA repair exonuclease rad1 homolog; Rad1-like DNA damage checkpoint proteinHomo sapiens (human)
Proto-oncogene c-FosCellular oncogene fos; G0/G1 switch regulatory protein 7Homo sapiens (human)
14-3-3 protein epsilon14-3-3EHomo sapiens (human)
GTP-binding protein RhebRas homolog enriched in brainHomo sapiens (human)
Ribonucleoside-diphosphate reductase subunit M2 BEC 1.17.4.1; TP53-inducible ribonucleotide reductase M2 B; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53R2Homo sapiens (human)
Ferroptosis suppressor protein 1FSP1; EC 1.6.5.-; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; AMID; p53-responsive gene 3 proteinHomo sapiens (human)
Bromodomain-containing protein 775 kDa bromodomain protein; Protein CELTIX-1Homo sapiens (human)
N-lysine methyltransferase KMT5AEC 2.1.1.-; H4-K20-HMTase KMT5A; Histone-lysine N-methyltransferase KMT5A; 2.1.1.361; Lysine N-methyltransferase 5A; Lysine-specific methylase 5A; PR/SET domain-containing protein 07; PR-Set7; PR/SET07; SET domain-containing protein 8Homo sapiens (human)
CCR4-NOT transcription complex subunit 3CCR4-associated factor 3; Leukocyte receptor cluster member 2Homo sapiens (human)
14-3-3 protein zeta/deltaProtein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
182 kDa tankyrase-1-binding proteinHomo sapiens (human)
Inhibitor of growth protein 2Inhibitor of growth 1-like protein; ING1Lp; p32; p33ING2Homo sapiens (human)
Fructose-2,6-bisphosphatase TIGAREC 3.1.3.46; TP53-induced glycolysis and apoptosis regulator; TP53-induced glycolysis regulatory phosphataseHomo sapiens (human)
CCR4-NOT transcription complex subunit 11Homo sapiens (human)
Protein PMLPromyelocytic leukemia protein; RING finger protein 71; Tripartite motif-containing protein 19Homo sapiens (human)
Tumor suppressor ARFAlternative reading frame; ARF; Cyclin-dependent kinase inhibitor 2A; p14ARFHomo sapiens (human)
Tumor protein p53-inducible nuclear protein 1Stress-induced protein; p53-dependent damage-inducible nuclear protein 1; p53DINP1Homo sapiens (human)
Inhibitor of growth protein 5p28ING5Homo sapiens (human)
CCR4-NOT transcription complex subunit 4EC 2.3.2.27; CCR4-associated factor 4; E3 ubiquitin-protein ligase CNOT4; Potential transcriptional repressor NOT4Hp; RING-type E3 ubiquitin transferase CNOT4Homo sapiens (human)
Protein NDRG1Differentiation-related gene 1 protein; DRG-1; N-myc downstream-regulated gene 1 protein; Nickel-specific induction protein Cap43; Reducing agents and tunicamycin-responsive protein; RTP; Rit42Homo sapiens (human)
CCR4-NOT transcription complex subunit 2CCR4-associated factor 2Homo sapiens (human)
Tumor protein p73p53-like transcription factor; p53-related proteinHomo sapiens (human)
Death domain-associated protein 6Daxx; hDaxx; ETS1-associated protein 1; EAP1; Fas death domain-associated proteinHomo sapiens (human)
Cytochrome c oxidase subunit 7A-related protein, mitochondrialCOX7a-related protein; Cytochrome c oxidase subunit VIIa-related protein; EB1Homo sapiens (human)
RNA polymerase II elongation factor ELLEleven-nineteen lysine-rich leukemia proteinHomo sapiens (human)
PHD finger protein 20Glioma-expressed antigen 2; Hepatocellular carcinoma-associated antigen 58; Novel zinc finger protein; Transcription factor TZPHomo sapiens (human)
Transcription factor E2F4E2F-4Homo sapiens (human)
Centromere protein JCENP-J; Centrosomal P4.1-associated protein; LAG-3-associated protein; LYST-interacting protein 1Homo sapiens (human)
p53-induced death domain-containing protein 1EC 3.4.21.-; Leucine-rich repeat and death domain-containing proteinHomo sapiens (human)
Metastasis-associated protein MTA2Metastasis-associated 1-like 1; MTA1-L1 protein; p53 target protein in deacetylase complexHomo sapiens (human)
Cytochrome c oxidase subunit 6A1, mitochondrialCytochrome c oxidase polypeptide VIa-liver; Cytochrome c oxidase subunit VIA-liver; COX VIa-LHomo sapiens (human)
Cytochrome c oxidase subunit 5A, mitochondrialCytochrome c oxidase polypeptide VaHomo sapiens (human)
Protein BTG2BTG family member 2; NGF-inducible anti-proliferative protein PC3Homo sapiens (human)
Transcription factor E2F8E2F-8Homo sapiens (human)
Apoptosis facilitator Bcl-2-like protein 14Bcl2-L-14; Apoptosis regulator Bcl-GHomo sapiens (human)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrialCytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1Homo sapiens (human)
Transcription initiation factor TFIID subunit 4RNA polymerase II TBP-associated factor subunit C; TBP-associated factor 4; Transcription initiation factor TFIID 130 kDa subunit; TAF(II)130; TAFII-130; TAFII130; Transcription initiation factor TFIID 135 kDa subunit; TAF(II)135; TAFII-135; TAFII135Homo sapiens (human)
TP53-regulated inhibitor of apoptosis 1Protein 15E1.1; WF-1; p53-inducible cell-survival factor; p53CSVHomo sapiens (human)
Protein SCO2 homolog, mitochondrialHomo sapiens (human)
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-likeAdenovirus E1B19K-binding protein B5; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A; NIP3-like protein X; NIP3LHomo sapiens (human)
Checkpoint protein HUS1hHUS1Homo sapiens (human)
Cell cycle checkpoint protein RAD17hRad17; RF-C/activator 1 homologHomo sapiens (human)
Methyl-CpG-binding domain protein 3Methyl-CpG-binding protein MBD3Homo sapiens (human)
Cytochrome c oxidase subunit 3EC 7.1.1.9; Cytochrome c oxidase polypeptide IIIHomo sapiens (human)
Cytochrome c oxidase subunit 6CCytochrome c oxidase polypeptide VIcHomo sapiens (human)
Cytochrome c oxidase subunit 8A, mitochondrialCytochrome c oxidase polypeptide VIII-liver/heart; Cytochrome c oxidase subunit 8-2Homo sapiens (human)
Cytochrome c oxidase subunit 5B, mitochondrialCytochrome c oxidase polypeptide VbHomo sapiens (human)
Cytochrome c oxidase subunit 6B1Cytochrome c oxidase subunit VIb isoform 1; COX VIb-1Homo sapiens (human)
Cytochrome c oxidase subunit 7C, mitochondrialCytochrome c oxidase polypeptide VIIcHomo sapiens (human)
TATA-box-binding proteinTATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunitHomo sapiens (human)
Transcription elongation factor A protein 1Transcription elongation factor S-II protein 1; Transcription elongation factor TFIIS.oHomo sapiens (human)
Cytochrome c oxidase subunit 7B, mitochondrialCytochrome c oxidase polypeptide VIIbHomo sapiens (human)
Growth arrest and DNA damage-inducible protein GADD45 alphaDNA damage-inducible transcript 1 protein; DDIT-1Homo sapiens (human)
General transcription factor IIH subunit 1Basic transcription factor 2 62 kDa subunit; BTF2 p62; General transcription factor IIH polypeptide 1; TFIIH basal transcription factor complex p62 subunitHomo sapiens (human)
Replication factor C subunit 4Activator 1 37 kDa subunit; A1 37 kDa subunit; Activator 1 subunit 4; Replication factor C 37 kDa subunit; RF-C 37 kDa subunit; RFC37Homo sapiens (human)
Replication factor C subunit 2Activator 1 40 kDa subunit; A1 40 kDa subunit; Activator 1 subunit 2; Replication factor C 40 kDa subunit; RF-C 40 kDa subunit; RFC40Homo sapiens (human)
Replication factor C subunit 3Activator 1 38 kDa subunit; A1 38 kDa subunit; Activator 1 subunit 3; Replication factor C 38 kDa subunit; RF-C 38 kDa subunit; RFC38Homo sapiens (human)
TuberinTuberous sclerosis 2 proteinHomo sapiens (human)
Transcription initiation factor TFIID subunit 6RNA polymerase II TBP-associated factor subunit E; Transcription initiation factor TFIID 70 kDa subunit; TAF(II)70; TAFII-70; TAFII70; Transcription initiation factor TFIID 80 kDa subunit; TAF(II)80; TAFII-80; TAFII80Homo sapiens (human)
Poly(rC)-binding protein 4Alpha-CP4Homo sapiens (human)
Death domain-containing protein CRADDCaspase and RIP adapter with death domain; RIP-associated protein with a death domainHomo sapiens (human)
Proline-rich protein 5Protein observed with Rictor-1; Protor-1Homo sapiens (human)
Fanconi anemia group C proteinProtein FACCHomo sapiens (human)
POU domain, class 4, transcription factor 1Brain-specific homeobox/POU domain protein 3A; Brain-3A; Brn-3A; Homeobox/POU domain protein RDC-1; Oct-T1Homo sapiens (human)
FACT complex subunit SSRP1Chromatin-specific transcription elongation factor 80 kDa subunit; Facilitates chromatin transcription complex 80 kDa subunit; FACT 80 kDa subunit; FACTp80; Facilitates chromatin transcription complex subunit SSRP1; Recombination signal sequence recognitiHomo sapiens (human)
POU domain, class 4, transcription factor 2Brain-specific homeobox/POU domain protein 3B; Brain-3B; Brn-3BHomo sapiens (human)
Transcription initiation factor TFIID subunit 10STAF28; Transcription initiation factor TFIID 30 kDa subunit; TAF(II)30; TAFII-30; TAFII30Homo sapiens (human)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoformPP2A B subunit isoform B'-gamma; PP2A B subunit isoform B56-gamma; PP2A B subunit isoform PR61-gamma; PP2A B subunit isoform R5-gamma; Renal carcinoma antigen NY-REN-29Homo sapiens (human)
General transcription factor IIH subunit 2Basic transcription factor 2 44 kDa subunit; BTF2 p44; General transcription factor IIH polypeptide 2; TFIIH basal transcription factor complex p44 subunitHomo sapiens (human)
General transcription factor IIH subunit 3Basic transcription factor 2 34 kDa subunit; BTF2 p34; General transcription factor IIH polypeptide 3; TFIIH basal transcription factor complex p34 subunitHomo sapiens (human)
Transcription initiation factor TFIID subunit 5Transcription initiation factor TFIID 100 kDa subunit; TAF(II)100; TAFII-100; TAFII100Homo sapiens (human)
Transcription initiation factor TFIID subunit 13Transcription initiation factor TFIID 18 kDa subunit; TAF(II)18; TAFII-18; TAFII18Homo sapiens (human)
Transcription initiation factor TFIID subunit 12Transcription initiation factor TFIID 20/15 kDa subunits; TAFII-20/TAFII-15; TAFII20/TAFII15Homo sapiens (human)
Transcription initiation factor TFIID subunit 9RNA polymerase II TBP-associated factor subunit G; STAF31/32; Transcription initiation factor TFIID 31 kDa subunit; TAFII-31; TAFII31; Transcription initiation factor TFIID 32 kDa subunit; TAFII-32; TAFII32Homo sapiens (human)
Cytochrome c oxidase assembly protein COX19hCOX19Homo sapiens (human)
Quinone oxidoreductase PIG3EC 1.-.-.-; Tumor protein p53-inducible protein 3; p53-induced gene 3 proteinHomo sapiens (human)
Metalloreductase STEAP3EC 1.16.1.-; Dudulin-2; Six-transmembrane epithelial antigen of prostate 3; Tumor suppressor-activated pathway protein 6; hTSAP6; pHyde; hpHydeHomo sapiens (human)
Transcription initiation factor TFIID subunit 2150 kDa cofactor of initiator function; RNA polymerase II TBP-associated factor subunit B; TBP-associated factor 150 kDa; Transcription initiation factor TFIID 150 kDa subunit; TAF(II)150; TAFII-150; TAFII150Homo sapiens (human)
General transcription factor IIH subunit 5General transcription factor IIH polypeptide 5; TFB5 ortholog; TFIIH basal transcription factor complex TTD-A subunitHomo sapiens (human)
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphataseType 1 PtdIns-4,5-P2 4-Ptase; EC 3.1.3.78; PtdIns-4,5-P2 4-Ptase I; Transmembrane protein 55BHomo sapiens (human)
Insulin-like growth factor-binding protein 3 receptorIGFBP-3R; Transmembrane protein 219Homo sapiens (human)
Junction-mediating and -regulatory proteinHomo sapiens (human)
Protein BANPBEN domain-containing protein 1; Btg3-associated nuclear protein; Scaffold/matrix-associated region-1-binding proteinHomo sapiens (human)
SET domain-containing protein 9EC 2.1.1.-Homo sapiens (human)
Zinc finger protein 420Homo sapiens (human)
RelA-associated inhibitorInhibitor of ASPP protein; Protein iASPP; NFkB-interacting protein 1; PPP1R13B-like proteinHomo sapiens (human)
DNA damage-binding protein 2DDB p48 subunit; DDBb; Damage-specific DNA-binding protein 2; UV-damaged DNA-binding protein 2; UV-DDB 2Homo sapiens (human)
HamartinTuberous sclerosis 1 proteinHomo sapiens (human)
Transcription initiation factor TFIID subunit 4BTranscription initiation factor TFIID 105 kDa subunit; TAF(II)105; TAFII-105; TAFII105Homo sapiens (human)
General transcription factor IIH subunit 4Basic transcription factor 2 52 kDa subunit; BTF2 p52; General transcription factor IIH polypeptide 4; TFIIH basal transcription factor complex p52 subunitHomo sapiens (human)
TATA-binding protein-associated factor 2N68 kDa TATA-binding protein-associated factor; TAF(II)68; TAFII68; RNA-binding protein 56Homo sapiens (human)
Transcription factor E2F7E2F-7Homo sapiens (human)
p53 apoptosis effector related to PMP-22Keratinocyte-associated protein 1; KCP-1; P53-induced protein PIGPC1; Transmembrane protein THWHomo sapiens (human)
Zinc finger protein 385AHematopoietic zinc finger protein; Retinal zinc finger proteinHomo sapiens (human)
AT-rich interactive domain-containing protein 3AARID domain-containing protein 3A; B-cell regulator of IgH transcription; Bright; Dead ringer-like protein 1; E2F-binding protein 1Homo sapiens (human)
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1RAD9, RAD1, HUS1-interacting nuclear orphan proteinHomo sapiens (human)
Regulator of cell cycle RGCCResponse gene to complement 32 protein; RGC-32Homo sapiens (human)
Chromatin modification-related protein MEAF6MYST/Esa1-associated factor 6; Esa1-associated factor 6 homolog; Protein EAF6 homolog; hEAF6; Sarcoma antigen NY-SAR-91Homo sapiens (human)
Transcription initiation factor TFIID subunit 9BNeuronal cell death-related protein 7; DN-7; Transcription initiation factor TFIID subunit 9-like; Transcription-associated factor TAFII31LHomo sapiens (human)
Helicase MOV-10EC 3.6.4.13; Armitage homolog; Moloney leukemia virus 10 proteinHomo sapiens (human)
p53-regulated apoptosis-inducing protein 1p53AIP1Homo sapiens (human)
DNA damage-inducible transcript 4 proteinHIF-1 responsive protein RTP801; Protein regulated in development and DNA damage response 1; REDD-1Homo sapiens (human)
Zinc finger protein PLAGL1Lost on transformation 1; LOT-1; Pleiomorphic adenoma-like protein 1; Tumor suppressor ZACHomo sapiens (human)
Nucleolar complex protein 2 homologProtein NOC2 homolog; NOC2-like protein; Novel INHAT repressorHomo sapiens (human)
RNA polymerase II subunit A C-terminal domain phosphataseEC 3.1.3.16; TFIIF-associating CTD phosphataseHomo sapiens (human)
FACT complex subunit SPT16Chromatin-specific transcription elongation factor 140 kDa subunit; FACT 140 kDa subunit; FACTp140; Facilitates chromatin transcription complex subunit SPT16; hSPT16Homo sapiens (human)
Glutathione peroxidase 2GPx-2; GSHPx-2; EC 1.11.1.9; Gastrointestinal glutathione peroxidase; Glutathione peroxidase-gastrointestinal; GPx-GI; GSHPx-GI; Glutathione peroxidase-related protein 2; GPRP-2Homo sapiens (human)

Compounds (26)

CompoundDescription
hydronium ion
Ammonium
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
carbon monoxideCarbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
Orthophosphate
Glutathione DisulfideA GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.
SuperoxidesHighly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
1,2-naphthoquinone
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
6-phosphonoglucono-delta-lactone
glutamate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
polyglutamineRN given for (D)-isomer
fructose 2,6-diphosphatephosphofructokinase activator synthesized via Mg-ATP & fructose-6-P
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)