Page last updated: 2024-12-08

6-phosphonoglucono-delta-lactone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

6-O-phosphono-D-glucono-1,5-lactone : An aldonolactone phosphate comprising D-glucono-1,5-lactone having the phosphate group at the 6-position. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID439452
CHEBI ID16938
SCHEMBL ID50310
MeSH IDM0140588

Synonyms (27)

Synonym
6-o-phosphono-d-glucono-1,5-lactone
[(2r,3s,4s,5r)-3,4,5-trihydroxy-6-oxooxan-2-yl]methyl dihydrogen phosphate
d-gluconic acid, delta-lactone, 6-(dihydrogen phosphate)
CHEBI:16938
[(2r,3s,4s,5r)-3,4,5-trihydroxy-6-oxotetrahydro-2h-pyran-2-yl]methyl dihydrogen phosphate
6-phosphonoglucono-delta-lactone
6-pgdl
delta-gluconolactone 6-phosphate
gluconic acid, delta-lactone, 6-(dihydrogen phosphate), d- (8ci)
d-gluconic acid, delta-lactone, 6-(dihydrogen phosphate) (9ci)
6-phosphoglucono-delta-lactone
d-glucono-delta-lactone-6-phosphate
d-6-phosphoglucono-delta-lactone
C01236
d-6-phospho-glucono-delta-lactone
d-glucono-1,5-lactone 6-phosphate
2641-81-8
6-phospho-d-glucono-1,5-lactone
SCHEMBL50310
{[(2r,3s,4s,5r)-3,4,5-trihydroxy-6-oxooxan-2-yl]methoxy}phosphonic acid
6-phosphonoglucono-d-lactone
6-(dihydrogen phosphate)-(8ci)-d-gluconic acid delta-lactone
6-(dihydrogen phosphate)-d-gluconic acid delta-lactone
6-(dihydrogen phosphate)-(9ci)-d-gluconic acid delta-lactone
Q245503
((2r,3s,4s,5r)-3,4,5-trihydroxy-6-oxotetrahydro-2h-pyran-2-yl)methyl dihydrogen phosphate
((2r,3s,4s,5r)-3,4,5-trihydroxy-6-oxotetrahydro-2h-pyran-2-yl)methyldihydrogenphosphate
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
Escherichia coli metaboliteAny bacterial metabolite produced during a metabolic reaction in Escherichia coli.
mouse metaboliteAny mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
aldonolactone phosphate
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (25)

PathwayProteinsCompounds
Metabolism14961108
Carbohydrate metabolism173120
Pentose phosphate pathway1330
Warburg Effect4652
Disease1278231
Infectious disease89579
Latent infection of Homo sapiens with Mycobacterium tuberculosis3232
Latent infection - Other responses of Mtb to phagocytosis3233
Cell redox homeostasis88
Gene expression (Transcription)90249
RNA Polymerase II Transcription72842
Generic Transcription Pathway60839
Transcriptional Regulation by TP5321931
TP53 Regulates Metabolic Genes4324
Pentose phosphate cycle ( Pentose phosphate cycle )2225
Infection with Mycobacterium tuberculosis7442
RuMP cycle, oxidative branch of the pentose phosphate pathway and formaldehyde assimilation112
Bacterial Infection Pathways12347
superpathway of central carbon metabolism346
superpathway of glycolysis and Entner-Doudoroff023
Relationship between glutathione and NADPH036
Pentose phosphate pathway05
Pentose pathway, non-oxidative branch07
Pentose phosphate metabolism05
Metabolism overview078
Biochemical pathways: part I0466

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.09

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index13.09 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.88 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (13.09)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]