n-Butyl glycidyl ether (BGE) is an important chemical intermediate used in the production of various polymers, resins, and coatings. Its synthesis typically involves the reaction of epichlorohydrin with n-butanol in the presence of a base catalyst. BGE is known for its excellent adhesion properties, low viscosity, and chemical resistance, making it a valuable component in epoxy resins, adhesives, and sealants. It is also employed in the production of polyurethane foams, plasticizers, and surfactants. Research on BGE focuses on its potential applications in advanced materials and its environmental impact. Studies are conducted to optimize its synthesis, explore its reactivity with different monomers, and evaluate its biodegradability and toxicity.'
n-butyl glycidyl ether: structure
ID Source | ID |
---|---|
PubMed CID | 17049 |
CHEMBL ID | 1530010 |
SCHEMBL ID | 29089 |
MeSH ID | M0079387 |
Synonym |
---|
propane, 1-butoxy-2,3-epoxy- |
NCIOPEN2_000973 |
2-(butoxymethyl)oxirane |
wln: t3otj b1o4 |
2426-08-6 |
3-butoxy-1,2-epoxypropane |
n-butyl glycidyl ether |
butyl glycidyl ether |
erl 0810 |
nsc-83413 |
ether, butyl glycidyl |
nsc83413 |
bge , |
oxirane, (butoxymethyl)- |
1-butoxy-2,3-epoxypropane |
glycidyl butyl ether |
2,3-epoxypropyl butyl ether |
NCGC00091562-01 |
tk 10408 |
hsdb 299 |
ether, butyl 2,3-epoxypropyl |
(butoxymethyl)oxirane |
butyl glycidyl ether, n- |
ccris 828 |
einecs 219-376-4 |
butyl 2,3-epoxypropyl ether |
nsc 83413 |
sipomer bge |
ageflex bge |
butyl 2,3-epoxy propyl ether |
brn 0103668 |
butyl glycidyl ether, 95% |
B0697 |
STK802039 |
AKOS005622683 |
NCGC00091562-02 |
oxirane, 2-(butoxymethyl)- |
unii-m03777a62s |
glycidyl n-butyl ether |
m03777a62s , |
NCGC00257227-01 |
dtxsid9024691 , |
dtxcid704691 |
tox21_303211 |
cas-2426-08-6 |
tox21_201746 |
NCGC00259295-01 |
BBL010943 |
25610-58-6 |
FT-0623309 |
1,2-epoxy-3-butoxypropane |
SCHEMBL29089 |
butyl-glycidyl-ether |
2-(butoxymethyl)oxirane # |
araldite rd-1 (salt/mix) |
heloxy 61 (salt/mix) |
epirez 501 |
CHEMBL1530010 |
(+/-)-butyl glycidyl ether |
o-butylglycidol |
1-butyl glycidyl ether |
mfcd00005145 |
J-519963 |
butyl glycidyl ether, 97% |
J-015422 |
CS-0238021 |
VS-02762 |
Q2404890 |
EN300-189104 |
Z409191626 |
Excerpt | Relevance | Reference |
---|---|---|
" However, while the results were not altogether conclusive, there was evidence of a significant increase in fetal death rates by the end of the first week after the highest dosage was administered." | ( Dominant lethal effects of n-butyl glycidyl ether in mice. Folse, DS; Frost, AF; Legator, MS; Onofre, A; Pullin, TG; Whorton, EB, 1983) | 0.56 |
" These agents demonstrate similar dose-response relationships over the range of concentrations up to 333 micrograms/ml." | ( Unscheduled DNA synthesis induced in human lymphocytes by butyl glycidyl ethers. Frost, AF; Legator, MS, 1982) | 0.26 |
Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
acetylcholinesterase | Homo sapiens (human) | Potency | 24.8883 | 0.0025 | 41.7960 | 15,848.9004 | AID1347397; AID1347398; AID1347399 |
SMAD family member 2 | Homo sapiens (human) | Potency | 19.6155 | 0.1737 | 34.3047 | 61.8120 | AID1346924 |
SMAD family member 3 | Homo sapiens (human) | Potency | 19.6155 | 0.1737 | 34.3047 | 61.8120 | AID1346924 |
retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 1.0871 | 0.0030 | 41.6115 | 22,387.1992 | AID1159552 |
retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 38.9000 | 0.0008 | 17.5051 | 59.3239 | AID1159531 |
estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 0.0033 | 0.0015 | 30.6073 | 15,848.9004 | AID1224848; AID1224849 |
pregnane X nuclear receptor | Homo sapiens (human) | Potency | 69.0083 | 0.0054 | 28.0263 | 1,258.9301 | AID1346982 |
estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 38.1571 | 0.0002 | 29.3054 | 16,493.5996 | AID743075 |
peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 55.2840 | 0.0010 | 19.4141 | 70.9645 | AID743191 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 69.5984 | 0.0237 | 23.2282 | 63.5986 | AID743222 |
aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 60.0192 | 0.0007 | 23.0674 | 1,258.9301 | AID651777; AID743085; AID743122 |
thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 27.4727 | 0.0003 | 23.4451 | 159.6830 | AID743065 |
nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 66.6712 | 0.0006 | 27.2152 | 1,122.0200 | AID743202; AID743219 |
survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 5.6234 | 0.1259 | 12.2344 | 35.4813 | AID1458 |
Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 27.4727 | 0.0023 | 19.5956 | 74.0614 | AID651631 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 6 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (16.67) | 29.6817 |
2010's | 2 (16.67) | 24.3611 |
2020's | 2 (16.67) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (38.59) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 1 (7.69%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 12 (92.31%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |