agrocin 84
Description
agrocin 84: contains glucose, deoxy arabinose & other yet unidentified sugars [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
agrocin 84 : A nucleotide conjugate that is produced by Agrobacterium radiobacter strain K-84. A 'Trojan horse' antibiotic used to control crown gall. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 14213375 |
| CHEBI ID | 185499 |
| MeSH ID | M0061871 |
Synonyms (6)
| Synonym |
|---|
| agrocin 84 |
| [5-(1,2-dihydroxyethyl)-3,4-dihydroxyoxolan-2-yl]oxy-n-[9-[5-[[[(2,3-dihydroxy-4-methylpentanoyl)amino]-hydroxyphosphoryl]oxymethyl]-3-hydroxyoxolan-2-yl]purin-6-yl]phosphonamidic acid |
| n-{[(5-{6-[({[5-(1,2-dihydroxyethyl)-3,4-dihydroxyoxolan-2-yl]oxy}(hydroxy)phosphoryl)amino]-9h-purin-9-yl}-4-hydroxyoxolan-2-yl)methoxy](hydroxy)phosphoryl}-2,3-dihydroxy-4-methylpentanimidic acid |
| CHEBI:185499 |
| agrocin |
| 59111-78-3 |
Research Excerpts
Overview
Agrocin 84 is a LeuRS inhibitor produced by the biocontrol agent Agrobacterium radiobacter K84. It is a plasmid-encoded, fraudulent adenine nucleotide antibiotic.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Agrocin 84 is a LeuRS inhibitor produced by the biocontrol agent Agrobacterium radiobacter K84 that targets pathogenic strains of A." | ( Plant tumour biocontrol agent employs a tRNA-dependent mechanism to inhibit leucyl-tRNA synthetase. Chopra, S; Cusack, S; Palencia, A; Reader, JS; Temple, BR; Tripathy, A; Velazquez-Campoy, A; Virus, C, 2013) | 1.11 |
| "Agrocin 84 is a plasmid-encoded, fraudulent adenine nucleotide antibiotic responsible for the preventative biological control of the plant cancer, crown gall. " | ( Agrocins and the biological control of crown gall. Kerr, A; Tate, ME, 1984) | 1.71 |
Drug Classes (1)
| Class | Description |
|---|---|
| purines | A class of imidazopyrimidines that consists of purine and its substituted derivatives. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Research
Studies (32)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 18 (56.25) | 18.7374 |
| 1990's | 7 (21.88) | 18.2507 |
| 2000's | 3 (9.38) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 2 (6.25) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 24.25
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (24.25) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 3 (9.38%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 29 (90.63%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||