Page last updated: 2024-12-08
norcepharadione b
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
norcepharadione B: isolated from Houttynia cordata; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 189168 |
| CHEMBL ID | 227414 |
| MeSH ID | M0427919 |
Synonyms (12)
| Synonym |
|---|
| 57576-41-7 |
| norcepharadione b |
| norcepharadione |
| CHEMBL227414 |
| 4h-dibenzo[de,g]quinoline-4,5(6h)-dione, 1,2-dimethoxy- |
| DTXSID80206205 |
| AKOS028108617 |
| 15,16-dimethoxy-10-azatetracyclo[7.7.1.0^{2,7.0^{13,17]heptadeca-1(17),2,4,6,8,13,15-heptaene-11,12-dione |
| norcepharadioneb |
| 15,16-dimethoxy-10-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(17),2,4,6,8,13,15-heptaene-11,12-dione |
| 1,2-dimethoxy-4h-dibenzo[de,g]quinoline-4,5(6h)-dione; norcepharadione |
| FS-10042 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (7)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1776041 | Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess assay | |||
| AID1776040 | Cytotoxicity against mouse BV2 cells assessed as reduction in cell viability at 1 to 25 uM after 24 hrs by MTT assay | |||
| AID284365 | Selectivity index, ratio of CC50 for BALB/c mouse T cells to IC50 for BALB/c mouse B cells | 2007 | Bioorganic & medicinal chemistry, Jan-15, Volume: 15, Issue:2 | Discovery and synthesis of new immunosuppressive alkaloids from the stem of Fissistigma oldhamii (Hemsl.) Merr. |
| AID284362 | Inhibition of ConA-induced BALB/c mouse T cell proliferation | 2007 | Bioorganic & medicinal chemistry, Jan-15, Volume: 15, Issue:2 | Discovery and synthesis of new immunosuppressive alkaloids from the stem of Fissistigma oldhamii (Hemsl.) Merr. |
| AID284364 | Selectivity index, ratio of CC50 for BALB/c mouse spleen cells to IC50 for BALB/c mouse T cells | 2007 | Bioorganic & medicinal chemistry, Jan-15, Volume: 15, Issue:2 | Discovery and synthesis of new immunosuppressive alkaloids from the stem of Fissistigma oldhamii (Hemsl.) Merr. |
| AID284363 | Inhibition of LPS-induced BALB/c mouse B cell proliferation | 2007 | Bioorganic & medicinal chemistry, Jan-15, Volume: 15, Issue:2 | Discovery and synthesis of new immunosuppressive alkaloids from the stem of Fissistigma oldhamii (Hemsl.) Merr. |
| AID284361 | Cytotoxicity against BALB/c mouse spleen cells | 2007 | Bioorganic & medicinal chemistry, Jan-15, Volume: 15, Issue:2 | Discovery and synthesis of new immunosuppressive alkaloids from the stem of Fissistigma oldhamii (Hemsl.) Merr. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.53
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.53) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||