Compounds > 4,4'-azobis(4-cyanovaleric acid)
Page last updated: 2024-12-07

4,4'-azobis(4-cyanovaleric acid)

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4,4'-azobis(4-cyanovaleric acid): a free radical initiator [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID92938
CHEMBL ID3185815
SCHEMBL ID27672
SCHEMBL ID786277
MeSH IDM0241028

Synonyms (68)

Synonym
AC-1880
LS-14095
4,4'-azo-bis(4-cyanopentanoic acid)
4,4'-azobis-4-cyanovaleric acid
4,4'-azobis(4-cyanovaleric acid), >=98.0% (t)
4-cyano-4-[(e)-(1-cyano-4-hydroxy-1-methyl-4-oxo-butyl)azo]pentanoic acid
4,4'-azobis-(4-cyanovaleric acid)
4,4'-azobis[4-cyanopentanoic acid]
nsc114466
nsc-114466
azobis(cyanovaleric acid)
valeric acid,4'-azobis[4-cyano-
4,4'-azobis[4-cyanovaleric acid]
cis-4,4'-azobis(4-cyanovaleric acid)
2638-94-0
pentanoic acid,4'-azobis[4-cyano-
4,4'-azobis(4-cyanovaleric acid), >=75%
valeric acid, 4,4'-azobis(4-cyano-
einecs 220-135-0
brn 1729856
kyselina 4,4'-azo-bis-(4-kyanvalerova) [czech]
4,4'-azobis(4-cyanovaleric acid)
nsc 114466
4,4'-azobis(4-cyanopentanoic acid)
pentanoic acid, 4,4'-azobis(4-cyano-
4,4'-azobis(4-cyanovaleric) acid
4,4'-azo-bis(4-cyanovaleric acid)
cas-2638-94-0
tox21_302513
dtxsid3044629 ,
dtxcid1024629
NCGC00256797-01
4,4'-diazene-1,2-diylbis(4-cyanopentanoic acid)
AKOS024348893
acva
abcva
4,4'-(diazene-1,2-diyl)bis(4-cyanopentanoic acid) (contains up to 18% water)
kyselina 4,4'-azo-bis-(4-kyanvalerova)
4-04-00-03382 (beilstein handbook reference)
pentanoic acid, 4,4'-(1,2-diazenediyl)bis(4-cyano-
AKOS015853607
4,4-azobis(4-cyanovaleric acid)
4-[2-(3-carboxy-1-cyano-1-methylpropyl)diazen-1-yl]-4-cyano-4-methylbutanoic acid
1041193-98-9
SCHEMBL27672
VFXXTYGQYWRHJP-UHFFFAOYSA-N
v-501
(e)-4,4'-(diazene-1,2-diyl)bis(4-cyanopentanoic acid)
VFXXTYGQYWRHJP-FOCLMDBBSA-N
SCHEMBL786277
c12h16n4o4
W-107175
4,4'-(diazene-1,2-diyl)bis(4-cyanopentanoic acid)
CHEMBL3185815
benzene, 1-bromo-4-(1-propyn-1-yl)-
mfcd00002799
pentanoic acid, 4,4'-azobis[4-cyano-
FT-0700071
4,4'-(diazene-1,2-diyl)bis(4-cyanopentanoic acid) (contains ca. 20% water)
Q4637047
FS-4446
pentanoic acid, 4,4'-(1,2-diazenediyl)bis[4-cyano-
4-[(4-carboxy-2-cyanobutan-2-yl)diazenyl]-4-cyanopentanoic acid
CS-W012275
DTXSID00859752
4,4'-(1e)-1,2-diazenediylbis[4-cyanopentanoic acid]
EN300-1705965
4-[(e)-2-(3-carboxy-1-cyano-1-methylpropyl)diazen-1-yl]-4-cyano-4-methylbutanoic acid
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (3)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency48.55770.003041.611522,387.1992AID1159552
pregnane X nuclear receptorHomo sapiens (human)Potency48.55770.005428.02631,258.9301AID1346982
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency76.95880.000323.4451159.6830AID743066
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's4 (40.00)29.6817
2010's2 (20.00)24.3611
2020's1 (10.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 40.57

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index40.57 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.47 (4.65)
Search Engine Demand Index51.85 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (40.57)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
nitrates
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.		210monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species
urea
pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.		210isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2,2'-azobis(2-amidinopropane)
2,2'-azobis(2-amidinopropane): water-soluble free-radical initiator		2.4120monoazo compound
lomefloxacin
lomefloxacin: structure given in first source. lomefloxacin : A fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery.		2.2510fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antimicrobial agent;
antitubercular agent;
photosensitizing agent
tyrosine
Tyrosine: A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.. tyrosine : An alpha-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring.		210amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
propane
Propane: A three carbon alkane with the formula H3CCH2CH3.		2.0310alkane;
gas molecular entity		food propellant
acetonitrile
acetonitrile: RN given refers to unlabeled cpd. acetonitrile : A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a methyl group.		2.0310aliphatic nitrile;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent
azobis(isobutyronitrile)
azobis(isobutyronitrile): blowing agent for elastomers & plastics; initiator for free radical reactions; structure		2.0310
d-alpha tocopherol
Vitamin E: A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.. tocopherol : A collective name for a group of closely related lipids that contain a chroman-6-ol nucleus substituted at position 2 by a methyl group and by a saturated hydrocarbon chain consisting of three isoprenoid units. They are designated as alpha-, beta-, gamma-, and delta-tocopherol depending on the number and position of additional methyl substituents on the aromatic ring. Tocopherols occur in vegetable oils and vegetable oil products, almost exclusively with R,R,R configuration. Tocotrienols differ from tocopherols only in having three double bonds in the hydrocarbon chain.. vitamin E : Any member of a group of fat-soluble chromanols that exhibit biological activity against vitamin E deficiency. The vitamers in this class consists of a chroman-6-ol core which is substituted at position 2 by a methyl group and (also at position 2) either a saturated or a triply-unsaturated hydrocarbon chain consisting of three isoprenoid units. The major function of vitamin E is to act as a natural antioxidant by scavenging free radicals and molecular oxygen.. (R,R,R)-alpha-tocopherol : An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.		1.9810alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite
n-isopropylacrylamide
N-isopropylacrylamide: can polymerize with glycidyl acrylate to form reactive water-soluble polymer that can react with the amino groups of enzymes-proteins or other ligands		2.0310
fluorescein-5-isothiocyanate
Fluorescein-5-isothiocyanate: Fluorescent probe capable of being conjugated to tissue and proteins. It is used as a label in fluorescent antibody staining procedures as well as protein- and amino acid-binding techniques.. fluorescein 5-isothiocyanate : The 5-isomer of fluorescein isothiocyanate. Acts as a fluorescent probe capable of being conjugated to tissue and proteins; used as a label in fluorescent antibody staining procedures as well as protein- and amino acid-binding techniques.		2.110fluorescein isothiocyanate
peroxynitric acid
[no description available]		210nitrogen oxoacid
balofloxacin
balofloxacin: showed potent bactericidal activity & inhibited the supercoiling activity of DNA gyrase of S. aureus, E. coli, & P aeruginosa; structure given in first source		2.2510
2,2,5,7,8-pentamethyl-1-hydroxychroman
2,2,5,7,8-pentamethyl-1-hydroxychroman: a Vitamin E derivative. chromanol : Any member of the class of chromanes that is chromane substituted by one or more hydroxy groups.		1.9810
valerates
Valerates: Derivatives of valeric acid, including its salts and esters.		3.73100short-chain fatty acid anion;
straight-chain saturated fatty acid anion		plant metabolite
3-nitrotyrosine
3-nitrotyrosine: RN given refers to parent cpd without isomeric designation. 3-nitrotyrosine : A nitrotyrosine comprising tyrosine having a nitro group at the 3-position on the phenyl ring.		2102-nitrophenols;
C-nitro compound;
nitrotyrosine;
non-proteinogenic alpha-amino acid
potassium permanganate
Potassium Permanganate: Permanganic acid (HMnO4), potassium salt. A highly oxidative, water-soluble compound with purple crystals, and a sweet taste. (From McGraw-Hill Dictionary of Scientific and Technical Information, 4th ed)		2.2510
2,4-dinitrophenylhydrazine
2,4-dinitrophenylhydrazine: structure. 2,4-dinitrophenylhydrazine : A C-nitro compound that is phenylhydrazine substituted at the 2- and 4-positions by nitro groups.		210C-nitro compound;
phenylhydrazines		reagent
phosphatidylcholines
Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.		2.41201,2-diacyl-sn-glycero-3-phosphocholine
ConditionIndicatedRelationship StrengthStudiesTrials
Benign Neoplasms
[description not available]		02.0510
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.		02.0510
Extravascular Hemolysis
[description not available]		02.3920
Hemolysis
The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.		02.3920