Page last updated: 2024-09-27

Chondromalacia Patellae

A degeneration of the ARTICULAR CARTILAGE of the PATELLA, caused by a decrease in sulfated MUCOPOLYSACCHARIDES in the ground substance. When accompanied by pain, it is sometimes considered part of or confused with PATELLOFEMORAL PAIN SYNDROME.

Synonyms(2)

Synonym
Chondromalacia Patellae
Patella, Chondromalacia Of

Research

Studies (3)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's1 (33.33)12.5806
2000's2 (66.67)18.1394
2010's0 (0.00)28.8240
2020's0 (0.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
lidocaine0medium11
methylprednisolone0medium11
glucosamine0low10
gadolinium dtpa0low10
chondroitin sulfates0low10

Protein Targets (112)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Potassium channel subfamily K member 30202
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20112
Potassium channel subfamily K member 90101
Luciferase1001
TDP1 protein2002
AR protein3003
cytochrome P450 family 3 subfamily A polypeptide 41001
pregnane X nuclear receptor2002
estrogen nuclear receptor alpha2002
euchromatic histone-lysine N-methyltransferase 22002
potassium voltage-gated channel subfamily H member 2 isoform d1001
Solute carrier family 22 member 1 0101
Nuclear receptor subfamily 1 group I member 20022
ATP-dependent translocase ABCB10101
D(2) dopamine receptor0101
Amine oxidase [flavin-containing] A0101
D(4) dopamine receptor0101
Amine oxidase [flavin-containing] B0101
Delta-type opioid receptor0202
Delta-type opioid receptor0202
Mu-type opioid receptor0213
Kappa-type opioid receptor0101
Histamine H1 receptor0101
Mu-type opioid receptor0213
D(3) dopamine receptor0101
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
Kappa-type opioid receptor0202
Mu-type opioid receptor0101
Mu-type opioid receptor0202
Potassium voltage-gated channel subfamily H member 20202
Sigma non-opioid intracellular receptor 10202
Sigma non-opioid intracellular receptor 10202
Sigma non-opioid intracellular receptor 10101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE1001
Chain A, Beta-lactamase1001
thioredoxin reductase1001
RAR-related orphan receptor gamma1001
GLS protein1001
Microtubule-associated protein tau1001
aldehyde dehydrogenase 1 family, member A11001
vitamin D (1,25- dihydroxyvitamin D3) receptor1001
IDH12002
chromobox protein homolog 11001
mitogen-activated protein kinase 11001
flap endonuclease 11001
geminin2002
cytochrome P450 3A4 isoform 11001
muscarinic acetylcholine receptor M11001
lamin isoform A-delta101001
Gamma-aminobutyric acid receptor subunit pi1001
ATP-binding cassette sub-family C member 30202
Multidrug resistance-associated protein 40202
Bile salt export pump0202
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Gamma-aminobutyric acid receptor subunit beta-11001
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Potassium voltage-gated channel subfamily A member 50101
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Sodium channel protein type 4 subunit alpha0101
Gamma-aminobutyric acid receptor subunit alpha-11001
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
GABA theta subunit1001
Canalicular multispecific organic anion transporter 10202
Multidrug and toxin extrusion protein 10101
Gamma-aminobutyric acid receptor subunit epsilon1001
Sodium channel protein type 3 subunit alpha0101
acetylcholinesterase1001
hypoxia-inducible factor 1 alpha subunit1001
PPM1D protein1001
GLI family zinc finger 31001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
progesterone receptor1001
nonstructural protein 11001
glucocorticoid receptor [Homo sapiens]1001
retinoid X nuclear receptor alpha1001
estrogen-related nuclear receptor alpha1001
G1001
bromodomain adjacent to zinc finger domain 2B1001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a1001
nuclear receptor subfamily 1, group I, member 21001
nuclear factor erythroid 2-related factor 2 isoform 21001
muscleblind-like protein 1 isoform 11001
Interferon beta1001
HLA class I histocompatibility antigen, B alpha chain 1001
Glucocorticoid receptor0202
Glycine receptor subunit alpha-10202
Androgen receptor0202
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Inositol hexakisphosphate kinase 11001
ATPase family AAA domain-containing protein 51001
Ataxin-21001
Nuclear receptor subfamily 1 group I member 20011
cytochrome P450 2C9, partial1001
ATP-dependent phosphofructokinase1001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]