rocaglaol has been researched along with Leukemia-P388* in 1 studies
1 other study(ies) available for rocaglaol and Leukemia-P388
| Article | Year |
|---|---|
Flavonol-cinnamate cycloadducts and diamide derivatives from Aglaia laxiflora.
Leaf extracts of the Malaysian plant Aglaia laxiflora provided two cytotoxic compounds, a new rocaglaol rhamnoside (1), a known rocaglaol (2), new (but inactive) flavonol-cinnamaminopyrrolidine adducts (3-6), and their probable biosynthetic precursors (7 and trimethoxyflavonol). All structures were elucidated primarily by 2D NMR spectroscopy. The structure and stereochemistry of aglaxiflorin A (3) were confirmed by single-crystal X-ray crystallography. Topics: Animals; Antineoplastic Agents, Phytogenic; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Heterocyclic Compounds, 3-Ring; Humans; Leukemia P388; Magnetic Resonance Spectroscopy; Malaysia; Mass Spectrometry; Mice; Molecular Conformation; Plants, Medicinal; Rats; Spectrometry, Mass, Fast Atom Bombardment; Tumor Cells, Cultured | 2000 |