Assay ID | Title | Year | Journal | Article |
AID304133 | Effect on hypothermia in mouse assessed as change in body temperature | 2007 | Journal of medicinal chemistry, Dec-13, Volume: 50, Issue:25
| Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine. |
AID304142 | Inhibition of nicotine-induced hypothermia in mouse assessed as change in body temperature at 0.5 ug/kg, sc | 2007 | Journal of medicinal chemistry, Dec-13, Volume: 50, Issue:25
| Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine. |
AID304143 | Inhibition of nicotine-induced antinociceptive effect in mouse at 0.5 ug/kg, sc by hot plate test | 2007 | Journal of medicinal chemistry, Dec-13, Volume: 50, Issue:25
| Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine. |
AID304128 | Displacement of [3H]epibatidine from alpha-4-beta-2 nAChR | 2007 | Journal of medicinal chemistry, Dec-13, Volume: 50, Issue:25
| Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine. |
AID304131 | Antinociceptive effect in mouse by tail flick test | 2007 | Journal of medicinal chemistry, Dec-13, Volume: 50, Issue:25
| Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine. |
AID146628 | Inhibition of [3H]nicotine binding to alpha4-beta2 nACh receptor from rat membranes | 2004 | Bioorganic & medicinal chemistry letters, Apr-19, Volume: 14, Issue:8
| Epibatidine structure-activity relationships. |
AID147084 | Binding affinity at homopentameric Nicotinic acetylcholine receptor alpha-7 subtype using [3H]S-(-)-nicotine as radioligand; Not determined | 1999 | Journal of medicinal chemistry, Aug-12, Volume: 42, Issue:16
| Molecular recognition in nicotinic acetylcholine receptors: the importance of pi-cation interactions. |
AID3056 | In vitro binding affinity towards (alpha-4)2(beta-2)3 neuronal nicotinic acetylcholine receptor in P2 membrane fractions of rat forebrain | 2003 | Journal of medicinal chemistry, May-22, Volume: 46, Issue:11
| 3D QSAR analyses-guided rational design of novel ligands for the (alpha4)2(beta2)3 nicotinic acetylcholine receptor. |
AID304132 | Antinociceptive effect in mouse by hot plate test | 2007 | Journal of medicinal chemistry, Dec-13, Volume: 50, Issue:25
| Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine. |
AID304134 | Inhibition of nicotine-induced antinociceptive effect in sc dosed mouse by tail flick test | 2007 | Journal of medicinal chemistry, Dec-13, Volume: 50, Issue:25
| Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine. |
AID146635 | Binding affinity at heteropentameric Nicotinic acetylcholine receptor alpha4-beta2 subtype using [3H]bungarotoxin as radioligand | 1999 | Journal of medicinal chemistry, Aug-12, Volume: 42, Issue:16
| Molecular recognition in nicotinic acetylcholine receptors: the importance of pi-cation interactions. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |