Compounds > difluorotoluene
Page last updated: 2024-12-06

difluorotoluene

Description

Difluorotoluene, also known as 2-fluorotoluene, is an aromatic compound with the formula C7H6F2. It is a colorless liquid with a characteristic odor. Difluorotoluene is a valuable building block in organic synthesis, used in the production of pharmaceuticals, pesticides, and dyes. It has been studied for its potential applications in various fields, including materials science and medicine. The compound is synthesized through various methods, including fluorination of toluene or by reacting 2-bromotoluene with potassium fluoride. Its effects on biological systems have been investigated, and its importance in various industrial processes makes it a subject of ongoing research.'

difluorotoluene: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID67983
SCHEMBL ID60954
MeSH IDM0286532

Synonyms (38)

Synonym
452-76-6
nsc-3465
nsc3465
2,4-difluorotoluene
benzene,4-difluoro-1-methyl-
benzene, 2,4-difluoro-1-methyl-
difluorotoluene
2,4-difluorotoluene, 99%
2,4-difluoro-1-methylbenzene
AKOS005063642
inchi=1/c7h6f2/c1-5-2-3-6(8)4-7(5)9/h2-4h,1h3
mpxdaibtywgbsl-uhfffaoysa-
D2351
A7140
A7350
2,4-difluorotolune
einecs 207-211-9
rmk2yu8ct4 ,
unii-rmk2yu8ct4
nsc 3465
BP-11380
FT-0610113
AM20060399
SCHEMBL60954
2,4-difluoro-toluene
W-106146
2,4-difluoro-1-methylbenzene #
J-507222
DTXSID70196429
mfcd00000332
AC-9822
2,4-difluoro toluene
2.4-difluoro methyl benzene
AS-33273
Q63409741
EN300-95446
toluene, 2,4-difluoro-
CS-W011136
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (23)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's5 (21.74)18.2507
2000's12 (52.17)29.6817
2010's6 (26.09)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 26.41

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index26.41 (24.57)
Research Supply Index3.18 (2.92)
Research Growth Index4.48 (4.65)
Search Engine Demand Index25.55 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (26.41)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (8.70%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other21 (91.30%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
adenine
[no description available]		3.26606-aminopurines;
purine nucleobase		Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
thymine
[no description available]		3.5280pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite
toluene
methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.		6.12230methylbenzene;
toluenes;
volatile organic compound		cholinergic antagonist;
fuel additive;
neurotoxin;
non-polar solvent
thymidine
[no description available]		2.730pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
benzimidazole
1H-benzimidazole : The 1H-tautomer of benzimidazole.		210benzimidazole;
polycyclic heteroarene
tyrosine
Tyrosine: A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.. tyrosine : An alpha-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring.		2.0310amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
methionine
Methionine: A sulfur-containing essential L-amino acid that is important in many body functions.. methionine : A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4.		2.0210aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
thiazoles
[no description available]		2.21101,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
2-aminopurine
2-Aminopurine: A purine that is an isomer of ADENINE (6-aminopurine).. aminopurine : Any purine having at least one amino substituent.. 2-aminopurine : The parent compound of the 2-aminopurines, comprising a purine core carrying an amino substituent at the 2-position.		2.42202-aminopurines;
nucleobase analogue		antimetabolite
deoxyuridine
[no description available]		210pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
azides
Azides: Organic or inorganic compounds that contain the -N3 group.. azide : Any nitrogen molecular entity containing the group -N3.		3.1710pseudohalide anionmitochondrial respiratory-chain inhibitor
thymidine 5'-triphosphate
thymidine 5'-triphosphate: RN given refers to parent cpd. dTTP : A thymidine phosphate having a triphosphate group at the 5'-position.		2.0610pyrimidine 2'-deoxyribonucleoside 5'-triphosphate;
thymidine phosphate		Escherichia coli metabolite;
mouse metabolite
nebularine
nebularine: structure. nebularine : A purine ribonucleoside that is 9H-purine attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage.		210purine ribonucleoside;
purines D-ribonucleoside		fungal metabolite
proline
Proline: A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.. proline : An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2.		2.2110amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid		algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
hydroxyl radical
Hydroxyl Radical: The univalent radical OH. Hydroxyl radical is a potent oxidizing agent.		2.1510oxygen hydride;
oxygen radical;
reactive oxygen species
oligonucleotides
[no description available]		2.7130
nitrophenols
Nitrophenols: PHENOLS carrying nitro group substituents.		2.1510
guanine
[no description available]		7.94402-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
7-deazaguanine
[no description available]		2.0310organic molecular entity
8-hydroxyguanine
7,8-dihydro-8-oxoguanine: was substituted for guanine at G(8), G(9), G(14), or G(15) in the human telomeric oligonucleotide 5'-d[AGGGTTAG(8)G(9)GTT AG(14)G(15)GTTAGGGTGT]-3'. 7,8-dihydro-8-oxoguanine : An oxopurine that is guanine in which the hydrogen at position 8 is replaced by an oxo group and in which the nitrogens at positions 7 and 9 each bear a hydrogen.		210oxopurine
ConditionIndicatedRelationship StrengthStudiesTrials
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