Page last updated: 2024-11-11

platyphylloside

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

platyphylloside: from the bark of black alder, inhibits the growth of sensitive and multi-drug resistant non-small cell lung carcinoma cells; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9826264
CHEMBL ID228449
MeSH IDM000594879

Synonyms (10)

Synonym
platyphylloside
CHEMBL228449
90803-80-8
(5s)-1,7-bis(4-hydroxyphenyl)-5-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyheptan-3-one
nsc799730
nsc-799730
nsc784874
nsc-784874
DTXSID501317051
3-heptanone, 5-(beta-d-glucopyranosyloxy)-1,7-bis(4-hydroxyphenyl)-, (5s)-
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (6)

Assay IDTitleYearJournalArticle
AID461110Cytotoxicity against CEF cells by MTT assay2010Bioorganic & medicinal chemistry letters, Feb-01, Volume: 20, Issue:3
Anti-influenza diarylheptanoids from the bark of Alnus japonica.
AID461108Antiviral activity against Influenza A virus (A/Korea/KBNP-0028/2000(H9N2)) infected in chicken egg after 5 days by hemagglutinination assay2010Bioorganic & medicinal chemistry letters, Feb-01, Volume: 20, Issue:3
Anti-influenza diarylheptanoids from the bark of Alnus japonica.
AID461109Selectivity index, ratio of CC50 for CEF cells to EC50 for Influenza A virus (A/Korea/KBNP-0028/2000(H9N2))2010Bioorganic & medicinal chemistry letters, Feb-01, Volume: 20, Issue:3
Anti-influenza diarylheptanoids from the bark of Alnus japonica.
AID480668Inhibition of anti-DNP-IgE-induced degranulation in rat RBL2H3 cells assessed as betahexosaminidase released at 100 uM after 20 mins by microplate reader assay2010Bioorganic & medicinal chemistry letters, May-01, Volume: 20, Issue:9
Inhibition of antigen-induced degranulation by aryl compounds isolated from the bark of Betula platyphylla in RBL-2H3 cells.
AID289010Antiproliferative activity against mouse L1578Y cells at 22 mM after 3 hrs by MTT assay2007Journal of natural products, Jun, Volume: 70, Issue:6
Biologically active natural products from Mongolian medicinal plants Scorzonera divaricata and Scorzonera pseudodivaricata.
AID480667Inhibition of anti-DNP-IgE-induced degranulation in rat RBL2H3 cells assessed as betahexosaminidase released at 10 uM after 20 mins by microplate reader assay2010Bioorganic & medicinal chemistry letters, May-01, Volume: 20, Issue:9
Inhibition of antigen-induced degranulation by aryl compounds isolated from the bark of Betula platyphylla in RBL-2H3 cells.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.63

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.63 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.42 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.63)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]