Page last updated: 2024-10-15

3'-deoxyinosine

Description

3'-deoxyinosine: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID135513783
CHEMBL ID4743800
SCHEMBL ID98800
MeSH IDM0190882

Synonyms (23)

Synonym
3'-deoxyinosine
inosine, 3'-deoxy-
13146-72-0
9-[(2r,3r,5s)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purin-6-one
j71u8qau3q ,
unii-j71u8qau3q
didanosine impurity d [ep impurity]
9-(3-deoxy-.beta.-d-erythro-pentofuranosyl)-1,9-dihydro-6h-purin-6-one [who-ip]
3'-deoxyinosine [who-ip]
didanosine impurity, 3'-deoxyinosine- [usp impurity]
didanosine impurity d
(-)-3'-deoxyinosine
SCHEMBL98800
RPZDLTVHZJHPAW-BAJZRUMYSA-N
9-((2r,3r,5s)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9h-purin-6-ol
9-[(2r,3r,5s)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1h-purin-6-one
9-(3-deoxypentofuranosyl)-9h-purin-6-ol
DTXSID70927210
Q27281284
A899111
CHEMBL4743800
9-[(2r,3r,5s)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-9h-purin-6-ol
F90166
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID1688790Antitrypanosomal activity against Trypanosoma brucei rhodesiense assessed as reduction in parasite growth incubated for 3 days by resazurin dye based fluorescence assay2020European journal of medicinal chemistry, Feb-15, Volume: 188C6-O-alkylated 7-deazainosine nucleoside analogues: Discovery of potent and selective anti-sleeping sickness agents.
AID1688793Selectivity index, ratio of EC50 for cytotoxicity against human MRC5 cells to EC50 for antitrypanosomal activity against Trypanosoma brucei rhodesiense2020European journal of medicinal chemistry, Feb-15, Volume: 188C6-O-alkylated 7-deazainosine nucleoside analogues: Discovery of potent and selective anti-sleeping sickness agents.
AID1688792Selectivity index, ratio of EC50 for cytotoxicity against human MRC5 cells to EC50 for antitrypanosomal activity against Trypanosoma brucei brucei2020European journal of medicinal chemistry, Feb-15, Volume: 188C6-O-alkylated 7-deazainosine nucleoside analogues: Discovery of potent and selective anti-sleeping sickness agents.
AID1688789Antitrypanosomal activity against Trypanosoma brucei brucei assessed as reduction in parasite growth incubated for 3 days by resazurin dye based fluorescence assay2020European journal of medicinal chemistry, Feb-15, Volume: 188C6-O-alkylated 7-deazainosine nucleoside analogues: Discovery of potent and selective anti-sleeping sickness agents.
AID1688791Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 3 days by resazurin dye based fluorescence assay2020European journal of medicinal chemistry, Feb-15, Volume: 188C6-O-alkylated 7-deazainosine nucleoside analogues: Discovery of potent and selective anti-sleeping sickness agents.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (18.18)18.7374
1990's3 (27.27)18.2507
2000's1 (9.09)29.6817
2010's2 (18.18)24.3611
2020's3 (27.27)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]