Page last updated: 2024-12-08
n,n-dimethyldopamine
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
N,N-dimethyldopamine: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 152427 |
CHEMBL ID | 347228 |
SCHEMBL ID | 67764 |
MeSH ID | M0124095 |
Synonyms (16)
Synonym |
---|
n,n-dmda |
CHEMBL347228 |
i5r8511l9n , |
1,2-benzenediol, 4-(2-(dimethylamino)ethyl)- |
unii-i5r8511l9n |
21581-37-3 |
n,n-dimethyldopamine |
1,2-benzenediol,4-[2-(dimethylamino)ethyl]- |
SCHEMBL67764 |
dimethyldopamine, n,n- |
XJTVXBWTYZCUJX-UHFFFAOYSA-N |
4-[2-(dimethylamino)ethyl]-1,2-benzenediol # |
DTXSID00175944 |
Q6951324 |
4-[2-(dimethylamino)ethyl]benzene-1,2-diol |
EN300-2914516 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (20)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID1131626 | Induction of pecking in im dosed pigeon | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131682 | Toxicity in dog up to 2 mg/kg, sc | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131620 | Inhibition of cardioaccelerator nerve stimulation in dog in presence of phentolamine | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131617 | Inhibition of 10 Hz electric current-induced cardioaccelerator nerve stimulation in iv dosed cat by cardiotachometer analysis | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131670 | Induction of hyperactivity in Sprague-Dawley rat at 3.13 to 50 ug administered into nucleus accumbens | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131638 | Induction of stereotyped behaviour in Sprague-Dawley rat at 2.5 to 20 mg/kg, sc | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131669 | Induction of stereotyped behaviour in intrastriatally dosed Sprague-Dawley rat at 3.13 to 50 ug administered into caudate putamen | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131623 | Induction of emesis in sc dosed dog | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131689 | Agonist activity at dopamine receptor in cat right atrium assessed as inhibition of cardiaccelerator nerve stimulation rate by cardiotachometer analysis | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131628 | Effect on heart rate in iv dosed cat | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131688 | Induction of hyperactivity in Sprague-Dawley rat at 2.5 to 20 mg/kg, sc | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131619 | Inhibition of 2 Hz electric current-induced cardioaccelerator nerve stimulation in iv dosed cat by cardiotachometer analysis in presence of 2 mg/kg, iv phentolamine | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131624 | Antagonism of apomorphine-induced emesis in sc dosed dog treated 15 mins prior to apomorphine challenge | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131618 | Inhibition of 2 Hz electric current-induced cardioaccelerator nerve stimulation in iv dosed cat by cardiotachometer analysis in presence of 0.2 mg/kg, iv haloperidol | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131671 | Induction of stereotyped behaviour in intrastriatally dosed Sprague-Dawley rat at 3.13 to 50 ug administered into nucleus accumbens | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131668 | Induction of hyperactivity in Sprague-Dawley rat at 3.13 to 50 ug administered into caudate putamen | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131615 | Inhibition of 2 Hz electric current-induced cardioaccelerator nerve stimulation in iv dosed cat by cardiotachometer analysis | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID1131646 | Induction of circling behaviour in Sprague-Dawley rat at 2.5 to 20 mg/kg, sc | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
AID132337 | Compound concentration that causes inhibition of [3H]-acetyl choline release by 50% was determined using reserpine-alpha MPT treated mice striatal slices | 1984 | Journal of medicinal chemistry, May, Volume: 27, Issue:5 | Dopaminergic agonists: comparative actions of amine and sulfonium analogues of dopamine. |
AID1131627 | Antagonism of apomorphine-induced pecking in im dosed pigeon treated 15 mins prior to apomorphine challenge | 1978 | Journal of medicinal chemistry, Mar, Volume: 21, Issue:3 | Preparation and biological actions of some symmetrically N,N-disubstituted dopamines. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (5)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 5 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.66
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.66) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |