Page last updated: 2024-12-07

n-butyrylglycine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

n-Butyrylglycine is a short-chain fatty acid derivative of glycine, with potential applications in various fields, including nutrition, medicine, and agriculture. Its synthesis typically involves the acylation of glycine with butyric anhydride or butyryl chloride. Studies have explored n-butyrylglycine's effects on various biological processes, such as its potential role in reducing inflammation, promoting gut health, and improving cognitive function. Interest in n-butyrylglycine stems from its ability to modulate metabolic pathways and its potential as a therapeutic agent. Research efforts are underway to understand its mechanism of action, its bioavailability, and its safety for potential clinical applications.'

butyrylglycine : A N-acylglycine obtained by formal condensation of the carboxy group of butyric acid with the amino group of glycine. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID88412
CHEBI ID89963
SCHEMBL ID233413
MeSH IDM0126821

Synonyms (32)

Synonym
EN300-31505
20208-73-5
2-butanamidoacetic acid
n-butyrylglycine
n-butanoylglycine
AKOS000152749
FT-0664165
butyrylglycine
2-(butanoylamino)acetic acid
unii-u29p5d8khl
einecs 243-599-6
u29p5d8khl ,
n-(1-oxobutyl)glycine
(butyrylamino)acetic acid
WPSSBBPLVMTKRN-UHFFFAOYSA-N
SCHEMBL233413
mfcd09812238
DTXSID80174056
F8880-5167
n-butyrylglycine, analytical reference material
glycine, n-(1-oxobutyl)-
butanamidoacetic acid
CHEBI:89963
2-butyramidoacetic acid
butyramidoacetic acid
n-butyryl-glycine
Q27162152
butyroyl glycine
CS-0059624
2-butanamidoaceticacid
HY-113119
Z285193236
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
human urinary metaboliteAny metabolite (endogenous or exogenous) found in human urine samples.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
N-acylglycineAn N-acyl-amino acid in which amino acid specified is glycine.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (66.67)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.41

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.41 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.36 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.41)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (16.67%)4.05%
Observational0 (0.00%)0.25%
Other5 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]