gamma-eudesmol profile

gamma-eudesmol: isomer of beta-eudesmol; found in plants and fungi [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

gamma-eudesmol : A eudesmane sesquiterpenoid in which the eudesmane skeleton carries a hydroxy substituent at C-11 and has a double bond between C-4 and C-5. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	6432005
CHEMBL ID	477900
CHEBI ID	62513
SCHEMBL ID	194293
MeSH ID	M0417651

Synonym
gamma-eudesmol
.gamma.-eudesmol
2-naphthalenemethanol, 1,2,3,4,4a,5,6,7-octahydro-.alpha.,.alpha.,4a,8-tetramethyl-, (2r-cis)-
uncineol
1209-71-8
C17124
machilol
selinenol
CHEMBL477900
chebi:62513 ,
2-[(2r,4ar)-4a,8-dimethyl-2,3,4,5,6,7-hexahydro-1h-naphthalen-2-yl]propan-2-ol
2-naphthalenemethanol, 1,2,3,4,4a,5,6,7-octahydro-alpha,alpha,4a,8-tetramethyl-, (2r-cis)-
(2r-cis)-1,2,3,4,4a,5,6,7-octahydro-alpha,alpha,4a,8-tetramethyl-2-naphthalenemethanol
unii-c3m974g2be
c3m974g2be ,
eudesm-4-en-11-ol
(+)-gamma-eudesmol
2-[(2r,4ar)-4a,8-dimethyl-1,2,3,4,4a,5,6,7-octahydronaphthalen-2-yl]propan-2-ol
SCHEMBL194293
[2r-cis]-1,2,3,4,4a,5,6,7-octahydro-.alpha.,.alpha.,4a,8-tetramethyl-2-naphthalenemethanol
2-((2r,4ar)-4a,8-dimethyl-1,2,3,4,4a,5,6,7-octahydronaphthalen-2-yl)propan-2-ol
WMOPMQRJLLIEJV-IUODEOHRSA-N
.gamma.-eudesmole
Q27131974
DTXSID301017639 ,
2-naphthalenemethanol, 1,2,3,4,4a,5,6,7-octahydro-.alpha.,.alpha.,4a,8-tetramethyl-, (2r,4ar)-
(2r,4ar)-1,2,3,4,4a,5,6,7-octahydro-.alpha.,.alpha.,4a,8-tetramethyl-2-naphthalenemethanol
(+)-.gamma.-eudesmol
eudesmol, .gamma.-
CS-0007112
HY-N0065
2-naphthalenemethanol, 1,2,3,4,4a,5,6,7-octahydro-alpha,alpha,4a,8-tetramethyl-, (2r,4ar)-
(2r,4ar)-1,2,3,4,4a,5,6,7-octahydro-alpha,alpha,4a,8-tetramethyl-2-naphthalenemethanol
eudesmol, gamma-
dtxcid001475824

Role	Description
volatile oil component	Any plant metabolite that is found naturally as a component of a volatile oil.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
eudesmane sesquiterpenoid	Any sesquiterpenoid having a eudesmane skeleton.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Assay ID	Title	Year	Journal	Article
AID360352	Cytotoxicity against human HepG2 cells by MTT assay	2001	Journal of natural products, May, Volume: 64, Issue:5	Cytotoxic constituents of the fruits of Cananga odorata.
AID360353	Cytotoxicity against human HepG2(2.2.15) cells by MTT assay	2001	Journal of natural products, May, Volume: 64, Issue:5	Cytotoxic constituents of the fruits of Cananga odorata.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (7.69)	29.6817
2010's	9 (69.23)	24.3611
2020's	3 (23.08)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	13 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
camphor, (+-)-isomer [no description available]	2.21	1	bornane monoterpenoid; cyclic monoterpene ketone	plant metabolite
deet N,N-diethyl-m-toluamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of m-toluic acid with the nitrogen of diethylamine. First developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas, it is the most widely used insect repellent worldwide.	2.08	1	benzamides; monocarboxylic acid amide	environmental contaminant; insect repellent; xenobiotic
linalool linalool: RN given refers to parent cpd without isomeric designation; structure. linalool : A monoterpenoid that is octa-1,6-diene substituted by methyl groups at positions 3 and 7 and a hydroxy group at position 3. It has been isolated from plants like Ocimum canum.	2.17	1	monoterpenoid; tertiary alcohol	antimicrobial agent; fragrance; plant metabolite; volatile oil component
alpha-pinene [no description available]	2.13	1	pinene	plant metabolite
alpha phellandrene alpha phellandrene: can be irritating to, & absorbed by the skin; ingestion can cause vomiting, diarrhea; RN given refers to cpd without isomeric designation; structure. alpha-phellandrene : One of a pair of phellandrene cyclic monoterpene double-bond isomers in which both double bonds are endocyclic (cf. alpha-phellandrene, where one of them is exocyclic).	2.25	1	cyclohexadiene; phellandrene	antimicrobial agent; plant metabolite; volatile oil component
gamma-terpinene gamma-terpinene: RN given refers to gamma-terpinene; structure. gamma-terpinene : One of three isomeric monoterpenes differing in the positions of their two double bonds (alpha- and beta-terpinene being the others). In gamma-terpinene the double bonds are at the 1- and 4-positions of the p-menthane skeleton.	2.13	1	cyclohexadiene; monoterpene	antioxidant; human xenobiotic metabolite; plant metabolite; volatile oil component
4-cymene 4-cymene: structure. p-cymene : A monoterpene that is toluene substituted by an isopropyl group at position 4.	2.25	1	monoterpene; toluenes	human urinary metabolite; plant metabolite; volatile oil component
fenchone, (+-)-isomer fenchone: RN given refers to cpd with unspecified isomeric designation. fenchone : A carbobicyclic compound that is fenchane in which the hydrogens at position 2 are replaced by an oxo group. It is a component of essential oil from fennel (Foeniculum vulgare).	2.21	1	carbobicyclic compound; cyclic terpene ketone; fenchane monoterpenoid	plant metabolite
myrcene myrcene: structure in first source. beta-myrcene : A monoterpene that is octa-1,6-diene bearing methylene and methyl substituents at positions 3 and 7 respectively.	2.17	1	monoterpene	anabolic agent; anti-inflammatory agent; flavouring agent; fragrance; plant metabolite; volatile oil component
beta-eudesmol beta-eudesmol: found in Atractylodes and other plants; RN given refers to (2R-(2alpha,4aalpha,8abeta))-isomer. beta-eudesmol : A carbobicyclic compound that is trans-decalin substituted at positions 2, 4a, and 8 by 2-hydroxypropan-2-yl, methyl and methylidene groups, respectively (the 2R,4aR,8aS-diastereoisomer).	3.39	6	carbobicyclic compound; eudesmane sesquiterpenoid; tertiary alcohol	volatile oil component
2-pinene oxide alpha-pinene oxide : An epoxide of alpha-pinene.	2.13	1	epoxide; pinane monoterpenoid	bacterial xenobiotic metabolite; fragrance; human metabolite
elemol elemol: monocyclic sespuiterpenoid tertiary alcohol; RN given refers to (1R-(1alpha,3alpha,4beta))-isomer; structure in first source. elemol : A sesquiterpenoid that is isopropanol which is substituted at position 2 by a (3S,4S)-3-isopropenyl-4-methyl-4-vinylcyclohexyl group.	2.91	3	olefinic compound; sesquiterpenoid; tertiary alcohol	fragrance; plant metabolite
alpha-eudesmol alpha-eudesmol: RN refers to (2alpha,4aalpha,8abeta)-isomer; from Juniperus virginiana; inhibits omega-agatoxin IVA-sensitive Ca2+ currents and synaptosomal Ca2+ uptake; structure in first source. alpha-eudesmol : A eudesmane sesquiterpenoid in which the eudesmane skeleton carries a hydroxy substituent at C-11 and has a double bond between C-3 and C-4.	3.39	6	eudesmane sesquiterpenoid; octahydronaphthalenes; tertiary alcohol	volatile oil component
lysicamine lysicamine: oxoaporphine alkaloid; structure in first source	2	1	alkaloid antibiotic; oxoaporphine alkaloid	metabolite
guaiol guaiol: structure in first source	2.13	1	guaiane sesquiterpenoid
(+)-delta-cadinene delta-cadinene: has antineoplastic activity; structure in first source. delta-cadinene : A member of the cadinene family of sesquiterpenes in which the double bonds are located at the 4-4a and 7-8 positions, and in which the isopropyl group at position 1 is cis to the hydrogen at the adjacent bridgehead carbon (position 8a).. (+)-delta-cadinene : A member of the cadinene family of sesquiterpenes in which the double bonds are located at the 4-4a and 7-8 positions, and in which the isopropyl group at position 1 is cis to the hydrogen at the adjacent bridgehead carbon (the 1S,8aR-enantiomer).	2.15	1	cadinene; delta-cadinene
cleistopholine cleistopholine: structure in first source	2	1
sesquiterpenes [no description available]	3.54	7
caryophyllene oxide caryophyllene oxide: has butyrylcholinesterase inhibitory activity; structure in first source. epoxide : Any cyclic ether in which the oxygen atom forms part of a 3-membered ring.	2.13	1	epoxide	metabolite
feruloyltyramine feruloyltyramine: structure given in first source; isolated from Cannabis sativa seeds, roots, leaves, and resin; induces hypothermia and motor incoordination in mice; moupinamide is (E)-isomer	2	1	tyramines	metabolite
humulene humulene: structure given in first source. (1E,4E,8E)-alpha-humulene : The (1E,4E,8E)-isomer of alpha-humulene.	2.58	2	alpha-humulene
caryophyllene caryophyllene: RN given refers to cpd without isomeric designation; structure given in first source	2.25	1
isomenthone isomenthone: from the essential oil of rose-scented geranium (Pelargonium spp.)	2.08	1	isomenthone
germacrone germacrone: isolated from Curcuma wenyujin	2.15	1	germacrane sesquiterpenoid; olefinic compound	androgen antagonist; anti-inflammatory agent; antifeedant; antifungal agent; antimicrobial agent; antineoplastic agent; antioxidant; antitussive; antiviral agent; apoptosis inducer; autophagy inducer; hepatoprotective agent; insecticide; neuroprotective agent; plant metabolite; volatile oil component
beta-elemene beta-elemene: increases tumor cell immunogenicity by inducing, at least in part, elevated expression of heat shock protein 70 on tumor cell surface. beta-elemene : A sesquiterpene that consists of cyclohexane bearing methyl and vinyl substituents at position 1 as well as two isopropenyl substituents at positions 2 and 4.. (-)-beta-elemene : The (-)-enantiomer of beta-elemene that has (1S,2S,4R)-configuration.	2.31	1	beta-elemene	antineoplastic agent
bornyl acetate [no description available]	2.17	1	acetate ester; monoterpenoid
beta-bisabolene (S)-beta-bisabolene : A beta-bisabolene which has (1S)-configuration.. beta-bisabolene : A bisabolene that is cyclohexene substituted by a methyl group at position 1 and a 6-methylhepta-1,5-dien-2-yl group at position 4.	2.13	1	beta-bisabolene

Condition	Relationship Strength	Studies
Hepatocellular Carcinoma [description not available]	2.08	1
Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.	2.08	1
Sarcoma 180 An experimental sarcoma of mice.	2.07	1

gamma-eudesmol

Description

Cross-References

Synonyms (35)

Roles (1)

Drug Classes (1)

Bioassays (2)

Research

Studies (13)

Market Indicators

Research Demand Index: 28.88

Study Types