Compounds > isomenthone
Page last updated: 2024-12-11

isomenthone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

isomenthone: from the essential oil of rose-scented geranium (Pelargonium spp.) [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
GeraniumgenusA plant genus of the family GERANIACEAE. Geranium is also used as a common name for PELARGONIUM.[MeSH]GeraniaceaeA plant family of the order Geraniales, subclass Rosidae, class Magnoliopsida.[MeSH]

Cross-References

ID SourceID
PubMed CID6432469
CHEBI ID36496
SCHEMBL ID4395963
MeSH IDM0578583

Synonyms (68)

Synonym
CHEBI:36496
(2s,5s)-2-isopropyl-5-methylcyclohexanone
18309-28-9
(1s,4s)-(-)-p-menthan-3-one
(1s,4s)-p-menthan-3-one
(2s,5s)-5-methyl-2-(propan-2-yl)cyclohexanone
(2s-cis)-5-methyl-2-(1-methylethyl)cyclohexanone
(-)-isomenthone
(1r,4r)-p-menthan-3-one
l-isomenthone
1074-95-9
p-menthan-3-one, cis-
cyclohexanone, 5-methyl-2-(1-methylethyl)-, cis-
.alpha.-isomenthone
p-menthan-3-one, (z)-
1-methyl-4-isopropyl-3-cyclohexanone, cis-
brn 3195564
(1)-isomenthone
fema no. 3460
cis-menthone
einecs 207-727-4
einecs 253-295-5
d,l-isomenthone
cyclohexanone, 5-methyl-2-(1-methylethyl)-, (z)-
cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2r,5r)-rel-
isomenthone
491-07-6
C17125
(2s,5s)-5-methyl-2-propan-2-ylcyclohexan-1-one
36977-92-1
(2s-cis)-2-(isopropyl)-5-methylcyclohexan-1-one
unii-11t7afm2ds
isomenthone, (-)-
11t7afm2ds ,
einecs 242-194-1
9wz3e2g6cl ,
isomenthone, (+/-)-
4-07-00-00087 (beilstein handbook reference)
unii-9wz3e2g6cl
dl-isomenthone [fhfi]
cyclohexanone, 5-methyl-2-(1-methylethyl)-, cis
cis-p-menthan-3-one
p-menthan-3-one, cis
(+/-)-isomenthone
cis-p-menthone
dl-isomenthone
SCHEMBL4395963
NFLGAXVYCFJBMK-IUCAKERBSA-N
cis-5-methyl-2-(1-methylethyl)-cyclohexanone
5-methyl-2-(1-methylethyl)cyclohexanone, (z)-
2-isopropyl-5-methyl-cyclohexanone, cis
(2r,5r)-2-isopropyl-5-methylcyclohexanone, rel-
isomenthon
mfcd00136032
(2s,5s)-5-methyl-2-(propan-2-yl)cyclohexan-1-one
(+-)-isomenthone
(1r,4r)-(+)-p-menthan-3-one
(+/-)-cis-p-menthan-3-one
cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2s,5s)-
(2s,5s)-2-isopropyl-5-methylcyclohexan-1-one
(1s,4s)-isomenthone
Q27116856
DTXSID501315467
STARBLD0039823
HY-N7259A
CS-0627180
alpha-isomenthone
EN300-157787

Research Excerpts

Overview

Isomenthone is a constituent of the essential oil of Mentha arvensis.

ExcerptReferenceRelevance
"Isomenthone is a constituent of the essential oil of Mentha arvensis L."( Isomenthone protects human dermal fibroblasts from TNF-α-induced death possibly by preventing activation of JNK and p38 MAPK.
Byun, S; Jung, E; Kim, M; Kim, S; Lee, J; Park, D, 2012)		2.54
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
isomenthone
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (100.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 39.96

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index39.96 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index52.19 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (39.96)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
menthol
Menthol: A monoterpene cyclohexanol produced from mint oils.		7.520p-menthane monoterpenoid;
secondary alcohol		volatile oil component
deet
N,N-diethyl-m-toluamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of m-toluic acid with the nitrogen of diethylamine. First developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas, it is the most widely used insect repellent worldwide.		2.0810benzamides;
monocarboxylic acid amide		environmental contaminant;
insect repellent;
xenobiotic
citronellol
citronellol: alcohol form of citronellal; found in rose oil; RN given refers to parent cpd without isomeric designation; structure. citronellol : A monoterpenoid that is oct-6-ene substituted by a hydroxy group at position 1 and methyl groups at positions 3 and 7.. insect repellent : An insecticide that acts as a repellent to insects.		2.0710monoterpenoidplant metabolite
limonene
Limonene: A naturally-occurring class of MONOTERPENES which occur as a clear colorless liquid at room temperature. Limonene is the major component in the oil of oranges which has many uses, including as flavor and fragrance. It is recognized as safe in food by the Food and Drug Administration (FDA).. limonene : A monoterpene that is cyclohex-1-ene substituted by a methyl group at position 1 and a prop-1-en-2-yl group at position 4 respectively.		7.520cycloalkene;
p-menthadiene		human metabolite
menthone
menthone : The trans-stereoisomer of p-menthan-3-one.. (-)-menthone : A menthone that is cyclohexanone substituted by a methyl and an isopropyl group at positions 5 and 2 respectively (the 2S,5R-stereoisomer).		7.520menthone
pulegone
pulegone: component of peppermint oil; RN given refers to cpd without isomeric designation; structure in Merck. (+)-pulegone : The (5R)-enantiomer of p-menth-4(8)-en-3-one.		2.830p-menth-4(8)-en-3-one
geraniol
[no description available]		2.07103,7-dimethylocta-2,6-dien-1-ol;
monoterpenoid;
primary alcohol		allergen;
fragrance;
plant metabolite;
volatile oil component
sesquiterpenes
[no description available]		2.0810
gamma-eudesmol
gamma-eudesmol: isomer of beta-eudesmol; found in plants and fungi. gamma-eudesmol : A eudesmane sesquiterpenoid in which the eudesmane skeleton carries a hydroxy substituent at C-11 and has a double bond between C-4 and C-5.		2.0810eudesmane sesquiterpenoidvolatile oil component
ConditionIndicatedRelationship StrengthStudiesTrials
Empyema, Gall Bladder
[description not available]		02.1110
Gallstone Disease
[description not available]		02.1110
Cholecystitis
Inflammation of the GALLBLADDER; generally caused by impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, or other diseases.		02.1110
Cholelithiasis
Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).		02.1110