Compounds > t 588
Page last updated: 2024-09-03

t 588 and imipramine

t 588 has been researched along with imipramine in 1 studies

Compound Research Comparison

Studies
(t 588)		Trials
(t 588)		Recent Studies (post-2010)
(t 588)		Studies
(imipramine)		Trials
(imipramine)		Recent Studies (post-2010) (imipramine)
320110,3201,359801

Protein Interaction Comparison

ProteinTaxonomyt 588 (IC50)imipramine (IC50)
Solute carrier family 22 member 2Homo sapiens (human)0.6
Solute carrier family 22 member 1 Homo sapiens (human)7.95
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)8.3
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)8.3
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.044
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.3
Cytochrome P450 2D6Homo sapiens (human)0.0051
D(2) dopamine receptorHomo sapiens (human)0.41
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.044
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.16
Sphingomyelin phosphodiesteraseHomo sapiens (human)5
DRattus norvegicus (Norway rat)2.0992
D(3) dopamine receptorRattus norvegicus (Norway rat)0.81
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.044
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)3.3884
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)3.3884
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)3.3884
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.16
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.074
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)3.3884
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.81
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.22
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 1DRattus norvegicus (Norway rat)0.044
D(4) dopamine receptorRattus norvegicus (Norway rat)0.81
5-hydroxytryptamine receptor 1FRattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 6Rattus norvegicus (Norway rat)0.044
Histamine H1 receptorRattus norvegicus (Norway rat)0.0001
Sodium-dependent serotonin transporterHomo sapiens (human)0.0074
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.81
5-hydroxytryptamine receptor 7 Rattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 5ARattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 5BRattus norvegicus (Norway rat)0.044
Histamine H1 receptorHomo sapiens (human)0.027
Sodium channel protein type 1 subunit alphaHomo sapiens (human)3.6
Sodium channel protein type 4 subunit alphaHomo sapiens (human)3.6
5-hydroxytryptamine receptor 3ARattus norvegicus (Norway rat)0.044
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.16
Histamine H2 receptorCavia porcellus (domestic guinea pig)1.9
D(2) dopamine receptorRattus norvegicus (Norway rat)0.81
Sodium channel protein type 7 subunit alphaHomo sapiens (human)3.6
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)8.3
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.3913
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)8.3
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)8.3
Sodium channel protein type 5 subunit alphaHomo sapiens (human)3.6
Sodium channel protein type 9 subunit alphaHomo sapiens (human)3.6
5-hydroxytryptamine receptor 4 Rattus norvegicus (Norway rat)0.044
Multidrug and toxin extrusion protein 1Homo sapiens (human)10
Sodium channel protein type 2 subunit alphaHomo sapiens (human)3.6
5-hydroxytryptamine receptor 3BRattus norvegicus (Norway rat)0.044
Sodium channel protein type 3 subunit alphaHomo sapiens (human)3.6
Solute carrier family 22 member 2Rattus norvegicus (Norway rat)9.9
Sodium channel protein type 11 subunit alphaHomo sapiens (human)3.6
Sodium channel protein type 8 subunit alphaHomo sapiens (human)3.6
TransporterRattus norvegicus (Norway rat)0.81
Sodium channel protein type 10 subunit alphaHomo sapiens (human)3.6

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ano, M; Hirata, K; Kitamura, K; Maekawa, M; Narita, H; Ono, S; Ukai, W; Yamafuji, T1

Other Studies

1 other study(ies) available for t 588 and imipramine

ArticleYear
Protective effect of R(-)-1-(benzo[b]thiophen-5-yl)- 2-[2-(N,N-diethylamino)ethoxy]ethanol hydrochloride (T-588), a novel cerebral activator, against experimental cerebral anoxia.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:1

    Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Diethylamines; Energy Metabolism; Glycolysis; Hypoxia, Brain; Imipramine; Male; Mice; Mice, Inbred Strains; Pentobarbital; Potassium Cyanide; Scopolamine; Sleep; Tacrine; Thiophenes

1993