valeramide profile

Valeramide is a white, crystalline solid with a mild odor. It is a derivative of valeric acid, a naturally occurring fatty acid. Valeramide is synthesized by reacting valeric acid with ammonia. It has been investigated for its potential therapeutic effects, including its ability to reduce anxiety, promote sleep, and alleviate pain. It is thought to exert its effects by interacting with neurotransmitters in the brain, particularly GABA. Research suggests that valeramide may have anticonvulsant properties and could be beneficial in managing epilepsy. However, more research is needed to fully understand its efficacy and safety.'

pentanamide : A monocarboxylic acid amide obtained by the formal condensation of valeric acid with ammonia. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	12298
CHEBI ID	16459
SCHEMBL ID	20284
MeSH ID	M0157310

Synonym
einecs 210-974-0
tkl9tn43qk ,
unii-tkl9tn43qk
ai3-24387
nsc 400223
AKOS009031546
EN300-19981
CHEBI:16459
LMFA08010002
nsc400223
n-valeramide
nsc-400223
pentanimidic acid
pentanamide
626-97-1
valeramide
C01842
inchi=1/c5h11no/c1-2-3-4-5(6)7/h2-4h2,1h3,(h2,6,7)
ipwfjlqdvfkjdu-uhfffaoysa-
V0002
A833929
STL283920
FT-0603495
SCHEMBL20284
valeric acid amide
valproic acid impurity e [ep impurity]
DTXSID3060827
valeramide, pharmaceutical impurity standard
mfcd00041895
pentanamide (valeramide)
pentanamide; valproic acid imp. e (ep); valeramide; valproic acid impurity e
Q6071464
ch3(ch2)3c(o)nh2
CS-0206049
FS-4458
Z104476278

Class	Description
monocarboxylic acid amide	A carboxamide derived from a monocarboxylic acid.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	5 (55.56)	18.7374
1990's	1 (11.11)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (33.33)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	9 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
ethylene glycol Ethylene Glycol: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.. ethanediol : Any diol that is ethane or substituted ethane carrying two hydroxy groups.. ethylene glycol : A 1,2-glycol compound produced via reaction of ethylene oxide with water.	1.97	1	ethanediol; glycol	metabolite; mouse metabolite; solvent; toxin
benzoic acid Benzoic Acid: A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.. benzoic acid : A compound comprising a benzene ring core carrying a carboxylic acid substituent.. aromatic carboxylic acid : Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring.	2	1	benzoic acids	algal metabolite; antimicrobial food preservative; drug allergen; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; human xenobiotic metabolite; plant metabolite
urea pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.	1.97	1	isourea; monocarboxylic acid amide; one-carbon compound	Daphnia magna metabolite; Escherichia coli metabolite; fertilizer; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
benzamide benzamide : An aromatic amide that consists of benzene bearing a single carboxamido substituent. The parent of the class of benzamides.	2	1	benzamides
cilostamide cilostamide: selective inhibitor of cyclic AMP phosphodiesterase & platelet aggregation; structure	1.97	1	quinolines
diazepam Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.. diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.	1.97	1	1,4-benzodiazepinone; organochlorine compound	anticonvulsant; anxiolytic drug; environmental contaminant; sedative; xenobiotic
rolipram [no description available]	1.97	1	pyrrolidin-2-ones	antidepressant; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
carbostyril Quinolones: A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.. quinolin-2(1H)-one : A quinolone that is 1,2-dihydroquinoline substituted by an oxo group at position 2.	1.97	1	monohydroxyquinoline; quinolone	bacterial xenobiotic metabolite
propionamide [no description available]	1.97	1	monocarboxylic acid amide; primary fatty amide
diphenyl diphenyl: RN given refers to unlabeled cpd; structure	2.33	2	aromatic fungicide; benzenes; biphenyls	antifungal agrochemical; antimicrobial food preservative
n-pentanoic acid n-pentanoic acid: RN given refers to unlabeled parent cpd. valeric acid : A straight-chain saturated fatty acid containing five carbon atoms.	2.07	1	short-chain fatty acid; straight-chain saturated fatty acid	plant metabolite
pentane Pentanes: Five-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives.. pentane : A straight chain alkane consisting of 5 carbon atoms.	2.07	1	alkane; volatile organic compound	non-polar solvent; refrigerant
hydrazine diamine : Any polyamine that contains two amino groups.	2	1	azane; hydrazines	EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
benzoylhydrazine benzoylhydrazine: inhibits copper-depleted bovine serum amine oxidase	2	1	carbohydrazide
valerates Valerates: Derivatives of valeric acid, including its salts and esters.	3.58	9	short-chain fatty acid anion; straight-chain saturated fatty acid anion	plant metabolite
atropine tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate : A tropane alkaloid that is (1R,5)-8-methyl-8-azabicyclo[3.2.1]octane substituted by a (3-hydroxy-2-phenylpropanoyl)oxy group at position 3.	6.92	1
iridoids Iridoids: A type of MONOTERPENES, derived from geraniol. They have the general form of cyclopentanopyran, but in some cases, one of the rings is broken as in the case of secoiridoid. They are different from the similarly named iridals (TRITERPENES).	1.97	1
valmane valtrates (combination): from Valerianaceae species; combination of valtratum, acevaltratum & didrovaltratum; structure (valtratum)	1.97	1

Condition	Indicated	Relationship Strength	Studies	Trials
Ascariasis Infection by nematodes of the genus ASCARIS. Ingestion of infective eggs causes diarrhea and pneumonitis. Its distribution is more prevalent in areas of poor sanitation and where human feces are used for fertilizer.	0	2.15	1	0
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	0	1.97	1	0

valeramide

Description

Cross-References

Synonyms (36)

Drug Classes (1)

Research

Studies (9)

Market Indicators

Research Demand Index: 27.63

Study Types