Page last updated: 2024-12-08
sc 58272
Description
Research Excerpts
Clinical Trials
Roles
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Study Profile
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Protein Interactions
Research Growth
Market Indicators
Description
SC 58272: inhibits myristoyl-CoA:protein N-myristoyltransferase; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 446385 |
CHEMBL ID | 6269 |
MeSH ID | M0273599 |
Synonyms (15)
Synonym |
---|
(s)-6-amino-2-[(s)-3-hydroxy-2-(2-{4-[4-(2-methyl-imidazol-1-yl)-butyl]-phenyl}-acetylamino)-propionylamino]-hexanoic acid (2-cyclohexyl-ethyl)-amide |
bdbm50034993 |
[cyclohexylethyl]-[[[[4-[2-methyl-1-imidazolyl-butyl]phenyl]acetyl]-seryl]-lysinyl]-amine |
MIM , |
sc 58272 |
sc-58272 , |
l-lysinamide, n-[[4-[4-(2-methyl-1h-imidazol-1-yl)butyl]phenyl]acetyl]-l-seryl-n1-(2-cyclohexylethyl)- |
164931-25-3 |
(2s)-6-amino-n-(2-cyclohexylethyl)-2-[[(2s)-3-hydroxy-2-[[2-[4-[4-(2-methylimidazol-1-yl)butyl]phenyl]acetyl]amino]propanoyl]amino]hexanamide |
DB02477 |
n-({4-[4-(2-methyl-1h-imidazol-1-yl)butyl]phenyl}acetyl)-l-seryl-n-(2-cyclohexylethyl)-l-lysinamide |
CHEMBL6269 , |
l-lysinamide, n-((4-(4-(2-methyl-1h-imidazol-1-yl)butyl)phenyl)acetyl)-l-seryl-n1-(2-cyclohexylethyl)- |
DTXSID00167824 |
AKOS040749436 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Protein Targets (4)
Inhibition Measurements
Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
Glycylpeptide N-tetradecanoyltransferase 2 | Homo sapiens (human) | IC50 (µMol) | 28.1903 | 0.0030 | 0.2362 | 0.8300 | AID143928; AID143934; AID143938; AID144059; AID144065; AID144069 |
Glycylpeptide N-tetradecanoyltransferase | Saccharomyces cerevisiae S288C | IC50 (µMol) | 0.0240 | 0.0240 | 0.0240 | 0.0240 | AID359051 |
Glycylpeptide N-tetradecanoyltransferase 1 | Homo sapiens (human) | IC50 (µMol) | 28.1903 | 0.0030 | 0.1587 | 0.8300 | AID143928; AID143934; AID143938; AID144059; AID144065; AID144069 |
N-acylethanolamine-hydrolyzing acid amidase | Homo sapiens (human) | IC50 (µMol) | 14.1000 | 0.7000 | 0.7000 | 0.7000 | AID144069 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Biological Processes (13)
Molecular Functions (10)
Ceullar Components (9)
Bioassays (12)
Research
Studies (10)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 5 (50.00) | 18.2507 |
2000's | 5 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 11.96
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (11.96) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 10 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |