| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
formamide
formimidic acid : A carboximidic acid that is formic acid in which the carbonyl oxygen is replaced by an imino group.. primary carboxamide : A carboxamide resulting from the formal condensation of a carboxylic acid with ammonia; formula RC(=O)NH2. | 1.96 | 1 | 0 | carboximidic acid;
formamides;
monocarboxylic acid amide;
one-carbon compound | solvent |
acetanilide
acetanilide: a phenylacetamide; use ACETANILIDES for the plural group meaning of the singular term. N-phenylacetamide : A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a phenyl group. | 1.96 | 1 | 0 | acetamides;
anilide | analgesic |
isoniazid
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.. hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC). | 2 | 1 | 0 | carbohydrazide | antitubercular agent;
drug allergen |
dimethylformamide
Dimethylformamide: A formamide in which the amino hydrogens are replaced by methyl groups.. N,N-dimethylformamide : A member of the class of formamides that is formamide in which the amino hydrogens are replaced by methyl groups. | 1.96 | 1 | 0 | formamides;
volatile organic compound | geroprotector;
hepatotoxic agent;
polar aprotic solvent |
n-methylacetamide
N-methylacetamide: RN given refers to parent cpd. N-methylacetamide : A monocarboxylic acid amide that is the N-methyl derivative of acetamide. | 1.96 | 1 | 0 | acetamides;
monocarboxylic acid amide | metabolite |
caprolactam
Caprolactam: Cyclic amide of caproic acid used in manufacture of synthetic fibers of the polyamide type. Can cause local irritation.. epsilon-caprolactam : A member of the class of caprolactams that is azepane substituted by an oxo group at position 2. | 1.96 | 1 | 0 | caprolactams | human blood serum metabolite |
2-hydroxypyridine
hydroxypyridine : Any member of the class of pyridines with at least one hydroxy substituent.. pyridin-2-ol : A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 2. | 1.96 | 1 | 0 | monohydroxypyridine | plant metabolite |
thiazoles
[no description available] | 2.08 | 1 | 0 | 1,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene | |
pyrimidine
pyrimidine : The parent compound of the pyrimidines; a diazine having the two nitrogens at the 1- and 3-positions. | 2.1 | 1 | 0 | diazine;
pyrimidines | Daphnia magna metabolite |
hydrazine
diamine : Any polyamine that contains two amino groups. | 2 | 1 | 0 | azane;
hydrazines | EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor |
benzohydroxamic acid
[no description available] | 2 | 1 | 0 | | |
nicotinic acid hydrazide
nicotinic acid hydrazide: structural homolog of isoniazid; structure given in first source | 2 | 1 | 0 | | |
n,n-dimethylbenzamide
[no description available] | 1.96 | 1 | 0 | | |
2-pyrrolidone
2-pyrrolidone: RN given refers to parent cpd. pyrrolidin-2-one : The simplest member of the class of pyrrolidin-2-ones, consisting of pyrrolidine in which the hydrogens at position 2 are replaced by an oxo group. The lactam arising by the formal intramolecular condensation of the amino and carboxy groups of gamma-aminobutyric acid (GABA). | 1.96 | 1 | 0 | pyrrolidin-2-ones | metabolite;
polar solvent |
n-ethylformamide
[no description available] | 1.96 | 1 | 0 | | |
2-piperidone
2-piperidone: structure given in first source. piperidin-2-one : A delta-lactam that is piperidine which is substituted by an oxo group at position 2. | 1.96 | 1 | 0 | delta-lactam;
piperidones | EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitor |
n-methyl-2-pyridone
N-methyl-2-pyridone: structure in first source | 1.96 | 1 | 0 | pyridone | |
n-methylpyrrolidone
1-methylpyrrolidin-2-one: structure in first source. N-methylpyrrolidin-2-one : A member of the class of pyrrolidine-2-ones that is pyrrolidin-2-one in which the hydrogen attached to the nitrogen is replaced by a methyl group. | 1.96 | 1 | 0 | lactam;
N-alkylpyrrolidine;
pyrrolidin-2-ones | polar aprotic solvent |
n-ethyl-2-pyrrolidone
N-ethyl-2-pyrrolidone: structure in first source | 1.96 | 1 | 0 | N-alkylpyrrolidine | |
deuterium
Deuterium: The stable isotope of hydrogen. It has one neutron and one proton in the nucleus. | 1.98 | 1 | 0 | dihydrogen | |
n,n-naphthaloylhydroxylamine
N,N-naphthaloylhydroxylamine: used for ultrahistochemical detection of Ca | 2 | 1 | 0 | | |
methylformamide
N-methylformamide : A member of the class of formamides having a N-methyl substituent. | 1.96 | 1 | 0 | formamides | |
dimethylacetamide
hallucinogen : Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations and other alterations of mood and thinking.. N,N-dimethylacetamide : A member of the class of acetamides that is acetamide in which the hydrogens attached to the N atom have been replaced by two methyl groups respectively. Metabolite observed in cancer metabolism. | 1.96 | 1 | 0 | acetamides;
monocarboxylic acid amide | human metabolite |
caracemide
[no description available] | 1.96 | 1 | 0 | | |
n-methylnicotinamide
N-methylnicotinamide: structure. N-methylnicotinamide : A pyridinecarboxamide that is nicotinamide in which one of the amide hydrogens is substituted by a methyl group. | 1.96 | 1 | 0 | pyridinecarboxamide | metabolite |
salicylhydroxamic acid
[no description available] | 2 | 1 | 0 | hydroxamic acid;
phenols | antibacterial drug;
EC 1.11.2.2 (myeloperoxidase) inhibitor;
EC 3.5.1.5 (urease) inhibitor;
trypanocidal drug |
fluorodeoxyglucose f18
Fluorodeoxyglucose F18: The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162) | 2.15 | 1 | 0 | 2-deoxy-2-((18)F)fluoro-D-glucose;
2-deoxy-2-fluoro-aldehydo-D-glucose | |
n-hydroxymethylbenzamide
[no description available] | 1.96 | 1 | 0 | | |
n-hydroxymethylformamide
N-hydroxymethylformamide: structure given in first source | 1.96 | 1 | 0 | | |
benzyloxyamine
benzyloxyamine: RN given refers to parent cpd | 2 | 1 | 0 | | |
sr 48968
SR 48968: structure given in first source; neurokinin A antagonist; tachykinin receptor antagonist; SR 48965 is the inactive R-enantiomer of SR 48968 | 7.02 | 1 | 0 | | |
n-methylpyridine-2-carboxamide
N-methylpyridine-2-carboxamide: structure in first source | 1.96 | 1 | 0 | | |
piperidines
Piperidines: A family of hexahydropyridines. | 2.02 | 1 | 0 | | |
heme
Heme: The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.. ferroheme : Any iron(II)--porphyrin coordination complex.. ferroheme b : Heme b in which the iron has oxidation state +2.. heme : A heme is any tetrapyrrolic chelate of iron. | 2 | 1 | 0 | | |
minocycline
Minocycline: A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant STAPHYLOCOCCUS infections.. minocycline : A tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5. | 2.08 | 1 | 0 | | |