N-ethylformamide is a colorless liquid with a faint ammonia-like odor. It is a useful solvent for a variety of organic and inorganic compounds. N-ethylformamide is synthesized by reacting formamide with ethyl alcohol in the presence of a catalyst. It is also a byproduct of the production of formamide and ethyl alcohol. N-ethylformamide is a versatile solvent used in a variety of industrial applications, including the manufacture of pharmaceuticals, pesticides, and dyes. It is also used as a plasticizer, an antifreeze, and a solvent for polymers. N-ethylformamide has been studied for its potential as a green solvent, as it is biodegradable and relatively non-toxic. It has also been investigated for its use in the synthesis of various organic compounds. N-ethylformamide is a relatively stable compound, but it can be hydrolyzed in the presence of water or acids. It is also a weak base. N-ethylformamide is a common impurity in formamide, and it can be removed by distillation. N-ethylformamide is a useful solvent in a variety of applications. It is a relatively safe and environmentally friendly compound, but it is important to handle it with care.'
| ID Source | ID |
|---|---|
| PubMed CID | 12319 |
| CHEMBL ID | 9421 |
| MeSH ID | M0108517 |
| Synonym |
|---|
| unii-vjf7xch5b6 |
| n-aethylformamid |
| vjf7xch5b6 , |
| n-aethylformamid [german] |
| einecs 211-001-2 |
| brn 1737860 |
| ai3-18804 |
| nsc 404522 |
| n-formylethylamine |
| n-ethylformamide |
| ethylformamide |
| formamide, n-ethyl- |
| nsc-404522 |
| nsc404522 |
| 627-45-2 |
| n-ethyl-formamide |
| CHEMBL9421 |
| FT-0693735 |
| F0188 |
| AKOS009156775 |
| DTXSID6060842 |
| mfcd00042672 |
| n-ethylformamide, >=99.0% (gc) |
| F19558 |
| n-ethyl formamide |
| 1-[(tert-butyl)oxycarbonyl]-3-[4-(trifluoromethyl)benzyl]piperidine-3-carboxylicacid |
| CS-0187584 |
| ethylaminocarbonyl |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID110026 | Antitumor activity was evaluated against the TLX5 lymphoma in mice measured for control as death day at a optimal dose 400 mg/Kg/day | 1986 | Journal of medicinal chemistry, Jun, Volume: 29, Issue:6 | Structural studies on bioactive compounds. 4. A structure-antitumor activity study on analogues of N-methylformamide. |
| AID122264 | Antitumor activity was evaluated against the TLX5 lymphoma in mice measured as treated to control at optimal dose. 800 mg/Kg/day | 1986 | Journal of medicinal chemistry, Jun, Volume: 29, Issue:6 | Structural studies on bioactive compounds. 4. A structure-antitumor activity study on analogues of N-methylformamide. |
| AID118235 | Antitumor activity was evaluated against the TLX5 lymphoma measured as mean death day for the treated at a optimal dose 400 mg/Kg/day | 1986 | Journal of medicinal chemistry, Jun, Volume: 29, Issue:6 | Structural studies on bioactive compounds. 4. A structure-antitumor activity study on analogues of N-methylformamide. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (33.64) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (11.11%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (88.89%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||