Page last updated: 2024-12-07

n-hydroxymethylbenzamide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

N-Hydroxymethylbenzamide (NHMB) is a compound that has garnered significant attention for its potential applications in various fields, including medicine, materials science, and organic synthesis. Its synthesis typically involves the reaction of benzamide with formaldehyde under appropriate conditions. NHMB has demonstrated noteworthy biological activities, exhibiting anti-inflammatory, anti-cancer, and antioxidant properties. Its unique structural features, characterized by the presence of both an amide group and a hydroxyl group, contribute to its versatility in diverse applications. Researchers are particularly interested in understanding its mechanism of action in relation to these biological activities. The investigation of its potential as a therapeutic agent, particularly for conditions involving inflammation or oxidative stress, remains a key area of research. '

Cross-References

ID SourceID
PubMed CID80493
SCHEMBL ID619878
MeSH IDM0113021

Synonyms (40)

Synonym
AC-19077
unii-lf48fi2yox
ai3-04006
nsc 5946
einecs 228-495-0
lf48fi2yox ,
benzamide, n-(hydroxymethyl)-
nsc-5946
nsc5946
6282-02-6
n-hydroxymethylbenzamide
n-methylolbenzamide
ENAMINE_001590
n-(hydroxymethyl)benzamide
OPREA1_582029
OPREA1_732152
benzamidomethanol
STK398353
n-(hydroxymethyl)benzamide, >=98.0%
AKOS000348806
HMS1398I06
A834017
FT-0629288
FT-0629287
SCHEMBL619878
n-(hydroxymetyl)-benzamide
n-hydroxymethyl benzamide
UOUBPDZUBVJZOQ-UHFFFAOYSA-N
W-104956
DTXSID80211930
AS-58941
n-monomethylolbenzamide
monomethylolbenzamide
mfcd00014415
Q27452341
D95962
CS-0116997
EN300-1268598
SY061595
Z56799838
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.53

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.53 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.53)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]