n-(3-aminopropyl)cadaverine profile

aminopropylcadaverine : A polyazaalkane that is the 1,4,11-triaza derivative of undecane. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	65523
CHEMBL ID	89035
CHEBI ID	64860
SCHEMBL ID	561079
MeSH ID	M0115719

Synonym
CHEMBL89035
chebi:64860 ,
56-19-9
aminopropylcadaverine
n-(3-aminopropyl)pentane-1,5-diamine
n-(3-aminopropyl)-1,5-pentanediamine
3-apcad
n-(3-aminopropyl)cadaverine
1,5-pentanediamine, n-(3-aminopropyl)-
SCHEMBL561079
DTXSID40204565
(5-aminopentyl)(3-aminopropyl)amine
Q27133504

Role	Description
Escherichia coli metabolite	Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
polyazaalkane	Any azaalkane in which two or more carbons in the chain are replaced by nitrogen.
triamine	Any polyamine that contained three amino groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathway	Proteins	Compounds
Aminopropylcadaverine Biosynthesis	3	7

Assay ID	Title	Year	Journal	Article
AID160317	Binding affinity to the mouse polyamine transporter on the L1210 cell surface	2003	Journal of medicinal chemistry, Jun-19, Volume: 46, Issue:13	Molecular requirements for targeting the polyamine transport system. Synthesis and biological evaluation of polyamine-anthracene conjugates.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	3 (30.00)	18.7374
1990's	3 (30.00)	18.2507
2000's	1 (10.00)	29.6817
2010's	3 (30.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	10 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
cadaverine [no description available]	3.6	9	alkane-alpha,omega-diamine	Daphnia magna metabolite; Escherichia coli metabolite; mouse metabolite; plant metabolite
sym-homospermidine sym-homospermidine: analog of spermidine isolated from sandal leaves (Santalum album L.); structure. sym-homospermidine : A polyazaalkane comprising undecane with three aza groups placed at the 1-, 6- and 11-positions.	2.38	2	polyazaalkane; triamine
putrescine [no description available]	2.41	2	alkane-alpha,omega-diamine	antioxidant; fundamental metabolite
spermidine [no description available]	3.4	7	polyazaalkane; triamine	autophagy inducer; fundamental metabolite; geroprotector
spermine [no description available]	2.41	2	polyazaalkane; tetramine	antioxidant; fundamental metabolite; immunosuppressive agent
eflornithine Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.. eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.	2.37	2	alpha-amino acid; fluoroamino acid	trypanocidal drug
dipropylenetriame N-(3-aminopropyl)-1,3-propanediamine: structure in first source	3	4	polyazaalkane	algal metabolite; plant metabolite
lysine Lysine: An essential amino acid. It is often added to animal feed.. lysine : A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6.. L-lysine : An L-alpha-amino acid; the L-isomer of lysine.	2.39	2	aspartate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; lysine; organic molecular entity; proteinogenic amino acid	algal metabolite; anticonvulsant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
methionine Methionine: A sulfur-containing essential L-amino acid that is important in many body functions.. methionine : A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4.	2.15	1	aspartate family amino acid; L-alpha-amino acid; methionine zwitterion; methionine; proteinogenic amino acid	antidote to paracetamol poisoning; human metabolite; micronutrient; mouse metabolite; nutraceutical
ornithine Ornithine: An amino acid produced in the urea cycle by the splitting off of urea from arginine.. ornithine : An alpha-amino acid that is pentanoic acid bearing two amino substituents at positions 2 and 5.	2.38	2	non-proteinogenic L-alpha-amino acid; ornithine	algal metabolite; hepatoprotective agent; mouse metabolite
octamethylenediamine octamethylenediamine: RN given refers to parent cpd. 1,8-diaminooctane : An alkane-alpha,omega-diamine in which the two amino groups are separated by eight methylene groups.	2.01	1	alkane-alpha,omega-diamine
methionylpuromycin [no description available]	1.97	1
metaperiodate Periodic Acid: A strong oxidizing agent.	1.97	1	iodine oxoacid
hypusine hypusine: N-terminal amino alcohol deriv of Lys occurring in bovine brain & in the urine of children with familial hyperlysinemia; minor descriptor (75-82); online & Index Medicus search LYSINE/AA (75-82). hypusine : An L-lysine derivative that is L-lysine bearing a (2R)-4-amino-2-hydroxybutyl substituent at position N(6).	1.97	1
norspermine 3,3,3-tetramine : A polyazaalkane consisting of a 13-membered straight chain alkane with aza-groups at the 1-, 5-, 9- and 13-positions.	2.01	1	polyazaalkane; tetramine
deoxyhypusine deoxyhypusine : An L-lysine derivative in which the N(6) of the lysine is substituted with a 4-aminobutyl group.	1.97	1	L-lysine derivative; non-proteinogenic L-alpha-amino acid	human metabolite
puromycin [no description available]	1.97	1	puromycins	antiinfective agent; antimicrobial agent; antineoplastic agent; EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor; EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor; nucleoside antibiotic; protein synthesis inhibitor
s-adenosylmethionine (R)-S-adenosyl-L-methionine : An S-adenosyl-L-methionine that has R-configuration.. S-adenosyl-L-methionine zwitterion : A zwitterionic tautomer of S-adenosyl-L-methionine arising from shift of the proton from the carboxy group to the amino group.. (R)-S-adenosyl-L-methionine zwitterion : An S-adenosyl-L-methionine zwitterion that has R-configuration; major species at pH 7.3.. (S)-S-adenosyl-L-methionine zwitterion : An S-adenosyl-L-methionine zwitterion that has S-configuration; major species at pH 7.3.. S-adenosyl-L-methionine : A sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine.	2.15	1	organic cation; sulfonium compound	coenzyme; cofactor; human metabolite; micronutrient; Mycoplasma genitalium metabolite; nutraceutical; Saccharomyces cerevisiae metabolite

n-(3-aminopropyl)cadaverine

Description

Cross-References

Synonyms (13)

Roles (1)

Drug Classes (2)

Pathways (1)

Bioassays (1)

Research

Studies (10)

Market Indicators

Research Demand Index: 12.44

Study Types