Page last updated: 2024-12-09
cochliophilin a
Description
cochliophilin A: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
Synonyms (22)
| Synonym |
|---|
| CHEBI:174680 |
| cochliophilin a |
| 9-hydroxy-6-phenyl-[1,3]dioxolo[4,5-g]chromen-8-one |
| OPREA1_580504 |
| CHEMBL364596 |
| SCHEMBL971282 |
| 9-hydroxy-6-phenyl-2h,8h-[1,3]dioxolo[4,5-g]chromen-8-one |
| 9-hydroxy-6-phenyl-8h-1,3-dioxolo[4,5-g][1]benzopyran-8-one |
| 110204-45-0 |
| 5-hydroxy-6,7-methylenedioxyflavone |
| BS-44933 |
| 9-hydroxy-6-phenyl-8h-[1,3]dioxolo[4,5-g]chromen-8-one |
| XC161677 |
| 9-oxidanyl-6-phenyl-(1,3)dioxolo(4,5-g)chromen-8-one |
| 9-hydroxy-6-phenyl-8h-1,3-dioxolo(4,5-g)(1)benzopyran-8-one |
| 9jl54rt3qz , |
| 8h-1,3-dioxolo(4,5-g)(1)benzopyran-8-one, 9-hydroxy-6-phenyl- |
| chembl-364596 |
| unii-9jl54rt3qz |
| DTXSID901187957 |
| F74924 |
| AKOS040736336 |
Drug Classes (1)
| Class | Description |
|---|
| flavones | A member of the class of flavonoid with a 2-aryl-1-benzopyran-4-one (2-arylchromen-4-one) skeleton and its substituted derivatives. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Bioassays (5)
| Assay ID | Title | Year | Journal | Article |
|---|
| AID247665 | Inhibitory activity against KB/MDR cell line after 72 hr of drug exposure | 2004 | Journal of medicinal chemistry, Oct-21, Volume: 47, Issue:22
| Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. |
| AID246154 | Concentration that causes 50% of maximum vinblastine accumulation in KB/MDR cells in 1 h | 2004 | Journal of medicinal chemistry, Oct-21, Volume: 47, Issue:22
| Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. |
| AID245888 | Maximum intracellular vinblastine accumulation of the KB/MDR cells caused by the compound in 1 h | 2004 | Journal of medicinal chemistry, Oct-21, Volume: 47, Issue:22
| Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. |
| AID247607 | Inhibitory activity against KB cell line after 72 h of drug exposure | 2004 | Journal of medicinal chemistry, Oct-21, Volume: 47, Issue:22
| Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. |
| AID237331 | cLogD was determined | 2004 | Journal of medicinal chemistry, Oct-21, Volume: 47, Issue:22
| Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.28
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.28 (24.57) | | Research Supply Index | 2.08 (2.92) | | Research Growth Index | 4.36 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |