cochliophilin A: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 927642 |
| CHEMBL ID | 364596 |
| CHEMBL ID | -364596 |
| CHEBI ID | 174680 |
| SCHEMBL ID | 971282 |
| MeSH ID | M0478863 |
| Synonym |
|---|
| CHEBI:174680 |
| cochliophilin a |
| 9-hydroxy-6-phenyl-[1,3]dioxolo[4,5-g]chromen-8-one |
| OPREA1_580504 |
| CHEMBL364596 |
| SCHEMBL971282 |
| 9-hydroxy-6-phenyl-2h,8h-[1,3]dioxolo[4,5-g]chromen-8-one |
| 9-hydroxy-6-phenyl-8h-1,3-dioxolo[4,5-g][1]benzopyran-8-one |
| 110204-45-0 |
| 5-hydroxy-6,7-methylenedioxyflavone |
| BS-44933 |
| 9-hydroxy-6-phenyl-8h-[1,3]dioxolo[4,5-g]chromen-8-one |
| XC161677 |
| 9-oxidanyl-6-phenyl-(1,3)dioxolo(4,5-g)chromen-8-one |
| 9-hydroxy-6-phenyl-8h-1,3-dioxolo(4,5-g)(1)benzopyran-8-one |
| 9jl54rt3qz , |
| 8h-1,3-dioxolo(4,5-g)(1)benzopyran-8-one, 9-hydroxy-6-phenyl- |
| chembl-364596 |
| unii-9jl54rt3qz |
| DTXSID901187957 |
| F74924 |
| AKOS040736336 |
| Class | Description |
|---|---|
| flavones | A member of the class of flavonoid with a 2-aryl-1-benzopyran-4-one (2-arylchromen-4-one) skeleton and its substituted derivatives. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID247665 | Inhibitory activity against KB/MDR cell line after 72 hr of drug exposure | 2004 | Journal of medicinal chemistry, Oct-21, Volume: 47, Issue:22 | Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. |
| AID246154 | Concentration that causes 50% of maximum vinblastine accumulation in KB/MDR cells in 1 h | 2004 | Journal of medicinal chemistry, Oct-21, Volume: 47, Issue:22 | Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. |
| AID245888 | Maximum intracellular vinblastine accumulation of the KB/MDR cells caused by the compound in 1 h | 2004 | Journal of medicinal chemistry, Oct-21, Volume: 47, Issue:22 | Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. |
| AID247607 | Inhibitory activity against KB cell line after 72 h of drug exposure | 2004 | Journal of medicinal chemistry, Oct-21, Volume: 47, Issue:22 | Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. |
| AID237331 | cLogD was determined | 2004 | Journal of medicinal chemistry, Oct-21, Volume: 47, Issue:22 | Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||