Page last updated: 2024-12-07

allitol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Allitol is a sugar alcohol derived from allose, a rare aldohexose. It is a white crystalline solid that is soluble in water. Allitol has been shown to have a number of interesting biological properties, including anti-inflammatory and antioxidant effects. It has also been shown to be effective in reducing blood sugar levels in diabetic animals. Allitol is currently being studied as a potential treatment for a variety of diseases, including diabetes, cancer, and inflammatory diseases.'

allitol: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID120700
CHEBI ID181263
SCHEMBL ID15545455
MeSH IDM0520063

Synonyms (29)

Synonym
(2r,3r,4s,5s)-hexane-1,2,3,4,5,6-hexol
CHEBI:181263
488-44-8
allitol
d-allitol
A832929
(2r,3r,4s,5s)-hexane-1,2,3,4,5,6-hexol;dulcitol
b3f996o6ju ,
unii-b3f996o6ju
AKOS006323056
S9347
allodulcit
allodulcitol
x9x ,
mfcd11519461
FBPFZTCFMRRESA-FBXFSONDSA-N
SCHEMBL15545455
W-202859
wurcs=2.0/1,1,0/[h2222h]/1/
allitol, >=98%
DTXSID60197607
allit
Q27467495
HY-N2840
l-allitol
CCG-266440
dulcitol; melampyrit; nsc 1944
CS-0023414
D88490

Research Excerpts

Overview

Allitol is a hexitol produced by reducing the rare sugar D-allulose with a metal catalyst under hydrogen gas. It is a kind of rare sugar alcohol with potential application value.

ExcerptReferenceRelevance
"Allitol is a rare sugar alcohol obtained by reducing d-allulose (d-psicose). "( Effects of Dietary Allitol on Body Fat Accumulation in Rats.
Higaki, S; Inai, R; Matsuo, T, 2022
)
2.49
"Allitol is a hexitol produced by reducing the rare sugar D-allulose with a metal catalyst under hydrogen gas. "( Safety evaluation and maximum use level for transient ingestion in humans of allitol.
Akimitsu, K; Inazu, T; Izumori, K; Kato, S; Kimura, I; Kishimoto, Y; Matsuo, T; Miyoshi, M; Mochizuki, S; Yoshida, H; Yoshihara, A, 2023
)
2.58
"Allitol is a kind of rare sugar alcohol with potential application value. "( Efficient Allitol Bioproduction from D-Fructose Catalyzed by Recombinant E. coli Whole Cells, and the Condition Optimization, Product Purification.
Li, C; Lin, H; Lin, J; Ren, Y; Song, X; Wen, X; Zhang, C, 2020
)
2.4

Toxicity

ExcerptReferenceRelevance
" To confirm the safe level of allitol, we conducted a series of safety assessments."( Safety evaluation and maximum use level for transient ingestion in humans of allitol.
Akimitsu, K; Inazu, T; Izumori, K; Kato, S; Kimura, I; Kishimoto, Y; Matsuo, T; Miyoshi, M; Mochizuki, S; Yoshida, H; Yoshihara, A, 2023
)
1.43
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
hexitol
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (23.08)29.6817
2010's2 (15.38)24.3611
2020's8 (61.54)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 30.82

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index30.82 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.97 (4.65)
Search Engine Demand Index33.17 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (30.82)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]