Page last updated: 2024-12-05

3,3'-dichlorobiphenyl

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

3,3'-Dichlorobiphenyl (PCB 15) is a polychlorinated biphenyl (PCB) congener. PCBs are synthetic organic compounds that were widely used in industrial applications due to their chemical stability, non-flammability, and electrical insulating properties. However, PCBs are persistent environmental pollutants and have been linked to a range of adverse health effects, including cancer, reproductive problems, and developmental delays. 3,3'-dichlorobiphenyl is a relatively less chlorinated PCB congener, meaning it has a lower number of chlorine atoms attached to the biphenyl molecule. This makes it more volatile and susceptible to environmental degradation compared to highly chlorinated congeners. 3,3'-dichlorobiphenyl has been found in various environmental compartments, including soil, water, and air. Its presence in the environment is primarily attributed to historical releases from industrial activities, such as manufacturing, waste disposal, and accidental spills. Due to its persistence and potential health risks, 3,3'-dichlorobiphenyl has been the subject of numerous studies focusing on its environmental fate, toxicity, and potential for bioaccumulation in living organisms. These studies aim to understand the pathways of exposure to 3,3'-dichlorobiphenyl and its potential impact on human and ecosystem health. 3,3'-dichlorobiphenyl is also used as a model compound for studying the biotransformation and metabolism of PCBs in organisms. Its relatively simple structure and the availability of analytical methods make it a suitable target for investigating the role of different enzymes and pathways involved in PCB detoxification. These studies can provide valuable insights into the mechanisms of PCB toxicity and aid in the development of strategies for managing PCB contamination. '

Cross-References

ID SourceID
PubMed CID16307
SCHEMBL ID817554
MeSH IDM0095055

Synonyms (31)

Synonym
pcb 11
pcb-11 cpd
1,1'-biphenyl, 3,3'-dichloro-
biphenyl, 3,3'-dichloro-
clophen a 30
55600-34-5
clophen a-30
ccris 5871
clophen a30
inchi=1/c12h8cl2/c13-11-5-1-3-9(7-11)10-4-2-6-12(14)8-10/h1-8
2050-67-1
3,3'-dichlorobiphenyl
3,3'-dichloro-1,1'-biphenyl
1-chloro-3-(3-chlorophenyl)benzene
clophen 30
62u12s7cjz ,
unii-62u12s7cjz
AKOS015903462
m,m'-dichlorobiphenyl
3,3'-dcb
SCHEMBL817554
3,3'-dichlorodiphenyl
3,3'-dichloro-1,1'-biphenyl #
DTXSID70872817
pcb no 11, analytical standard
pcb no. 11 10 microg/ml in isooctane
pcb no. 11
3,3/'-dichlorobiphenyl
AMY450
Q27263514
m,m'-dichlordiphenyl
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (30)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (6.67)18.7374
1990's4 (13.33)18.2507
2000's6 (20.00)29.6817
2010's13 (43.33)24.3611
2020's5 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 16.71

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index16.71 (24.57)
Research Supply Index3.47 (2.92)
Research Growth Index4.99 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (16.71)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (3.23%)6.00%
Case Studies1 (3.23%)4.05%
Observational0 (0.00%)0.25%
Other29 (93.55%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]