Compounds > 2-formylphenylboronic acid
Page last updated: 2024-12-08

2-formylphenylboronic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-formylphenylboronic acid: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID292189
CHEMBL ID139725
SCHEMBL ID233987
MeSH IDM0526565

Synonyms (60)

Synonym
AC-5349
EN300-40906
40138-16-7
2-formylphenylboronic acid
nsc-157839
nsc157839
2-formylphenylboronic acid, >=95.0%
STK503703
(2-formylphenyl)boronic acid
benzaldehyde-2-boronic acid
B1873 ,
2-benzaldehyde boronic acid
CHEMBL139725 ,
2-formylbenzeneboronic acid
AKOS000264852
bdbm50067904
A6709
2-boronobenzaldehyde; 2-(dihydroxyboryl)benzaldehyde;2-formylphenylboronic acid
2-formylphenyl-boronic acid
2-formylphenylboronicacid
2-(dihydroxyboryl)benzaldehyde
o-formylphenylboronic acid
(2-formylphenyl)boronic acid;2,5-dimethylphenyl isocyanate
A825090
2-boronobenzaldehyde
FT-0612460
AM20040404
boronic acid, b-(2-formylphenyl)-
AB03992
VT1189
SCHEMBL233987
AS-2515
2-formyl-phenylboronic acid
2-formyl benzene boronic acid
2-formyl benzeneboronic acid
2-formylphenyl boronic acid
2-formylbenzene boronic acid
2-formyl phenyl boronic acid
2-formyl phenylboronic acid
boronic acid, (2-formylphenyl)-
2-formylphenylboronic acid #
F0001-1132
mfcd00151822
J-509539
CS-W007320
BBL104402
(2-formylphenyl)boronic acid;2-boronobenzaldehyde;benzaldehyde-2-boronic acid;2-(dihydroxyboryl)benzaldehyde
BCP27349
SY010671
(2-formylphenyl)boronic-10b acid
noname_873
DTXSID30901733
2-fpba
2-formyl boronic acid
benzeneboronic acid, o-formyl-
o-formylbenzeneboronic acid
mt69hy4fnf ,
b-(2-formylphenyl)boronic acid
unii-mt69hy4fnf
Z415628158
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (2)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Beta-lactamaseEscherichia coli K-12Ki25.30000.02703.64137.3000AID38398
Angiotensin-converting enzymeRattus norvegicus (Norway rat)Ki25.30000.00011.96427.3000AID38398
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (2)

Processvia Protein(s)Taxonomy
antibiotic catabolic processBeta-lactamaseEscherichia coli K-12
response to antibioticBeta-lactamaseEscherichia coli K-12
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (2)

Processvia Protein(s)Taxonomy
beta-lactamase activityBeta-lactamaseEscherichia coli K-12
hydrolase activityBeta-lactamaseEscherichia coli K-12
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (2)

Processvia Protein(s)Taxonomy
outer membrane-bounded periplasmic spaceBeta-lactamaseEscherichia coli K-12
periplasmic spaceBeta-lactamaseEscherichia coli K-12
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1488822Cytotoxicity against human ARPE19 cells assessed as reduction in cell viability up to 100 uM after 72 hrs by CellTiter-blue assay2017Bioorganic & medicinal chemistry letters, 09-01, Volume: 27, Issue:17
The hydrolytic susceptibility of prochelator BSIH in aqueous solutions.
AID1488821Cytoprotective activity against H2O2-induced toxicity in human ARPE19 cells pretreated for 5 hrs followed by H2O2 addition after 19 hrs by CellTiter-blue assay2017Bioorganic & medicinal chemistry letters, 09-01, Volume: 27, Issue:17
The hydrolytic susceptibility of prochelator BSIH in aqueous solutions.
AID38398Inhibitory activity against Escherichia coli AmpC beta-lactamase.1998Journal of medicinal chemistry, Nov-05, Volume: 41, Issue:23
Structure-based enhancement of boronic acid-based inhibitors of AmpC beta-lactamase.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's2 (11.76)29.6817
2010's12 (70.59)24.3611
2020's2 (11.76)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 31.89

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index31.89 (24.57)
Research Supply Index2.89 (2.92)
Research Growth Index5.46 (4.65)
Search Engine Demand Index34.17 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (31.89)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other17 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
glycine
[no description available]		2.0610alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
3-nitrobenzeneboronic acid
[no description available]		1.9910
benzo(b)thiophene-2-boronic acid
benzo(b)thiophene-2-boronic acid: inhibits AmpC beta-lactamase; structure in first source		1.9910
isoniazid
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.. hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).		2.1510carbohydrazideantitubercular agent;
drug allergen
boranes
Boranes: The collective name for the boron hydrides, which are analogous to the alkanes and silanes. Numerous boranes are known. Some have high calorific values and are used in high-energy fuels. (From Grant & Hackh's Chemical Dictionary, 5th ed). borane : The simplest borane, consisting of a single boron atom carrying three hydrogens.. boranes : The molecular hydrides of boron.		2.1710boranes;
mononuclear parent hydride
salicylaldehyde
o-hydroxybenzaldehyde: structure in first source		2.1510hydroxybenzaldehydenematicide;
plant metabolite
1-phenethylamine
1-phenethylamine: RN given refers to cpd without isomeric designation. 1-phenylethylamine : A phenylethylamine that is ethylamine substituted by a phenyl group at position 1.		2.4620phenylethylaminehuman metabolite
glyoxal
[no description available]		2.1510dialdehydeagrochemical;
allergen;
pesticide;
plant growth regulator
2-naphthol
2-naphthol: RN given refers to parent cpd. 2-naphthol : A naphthol carrying a hydroxy group at position 2.. naphthols : Any hydroxynaphthalene derivative that has a single hydroxy substituent.		2.7730naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
hydrazine
diamine : Any polyamine that contains two amino groups.		2.1110azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
(s)-binol
(1,1'-binaphthalene)-2,2'-diol: structure in first source		2.0410naphthols
hexahydrophthalic acid
hexahydrophthalic acid: a major metabolite of hexahydrophthalic anhydride		2.0710
diphenylborinic acid
diphenylborinic acid: structure given in first source		1.9910
n-butylboronic acid
[no description available]		1.9910
gold
Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.		2.1110copper group element atom;
elemental gold
benzeneboronic acid
[no description available]		2.4520boronic acids
4-bromophenylboric acid
[no description available]		1.9910
3-aminobenzeneboronic acid
[no description available]		1.9910
n-dansyl-3-aminobenzeneboronic acid
N-dansyl-3-aminobenzeneboronic acid: potent serine protease inhibitor; fluorescent boronic acid which reversibly binds to bacterial cell walls; structure given in first source		1.9910
4-methoxyphenylboronic acid
4-methoxyphenylboronic acid: structure in first source		1.9910
1,4-phenylenebis(boronic acid)
1,4-phenylenebis(boronic acid): structure in first source		1.9910
thiophene-3-boronic acid
thiophene-3-boronic acid: structure in first source		1.9910
chitosan
[no description available]		2.5920
salinazid
[no description available]		2.1510aromatic carboxylic acid;
pyridinemonocarboxylic acid
ConditionIndicatedRelationship StrengthStudiesTrials