Page last updated: 2024-09-27
Acalculia
Impairment in mathematical abilities secondary to a damage to a specific region of the brain often caused by a stroke, tumor, or trauma.
Synonyms(6)
| Synonym |
|---|
| Acquired Dyscalculia |
| Primary Dyscalculia |
| Acalculia |
| Secondary Acalculia |
| Developmental Dyscalculia |
| Dyscalculia |
Research Excerpts
Research
Studies (12)
| Timeframe | Studies, This Condition (%) | All Conditions % |
|---|
| pre-1990 | 2 (16.67) | 23.3326 |
| 1990's | 0 (0.00) | 12.5806 |
| 2000's | 0 (0.00) | 18.1394 |
| 2010's | 8 (66.67) | 28.8240 |
| 2020's | 2 (16.67) | 9.53 |
Protein Targets (66)
| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Amyloid-beta precursor protein | 0 | 1 | 0 | 1 |
| Luciferase | 3 | 0 | 0 | 3 |
| pregnane X receptor | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
| RAR-related orphan receptor gamma | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 1 | 0 | 0 | 1 |
| AR protein | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 2 | 0 | 0 | 2 |
| retinoid X nuclear receptor alpha | 1 | 0 | 0 | 1 |
| estrogen-related nuclear receptor alpha | 3 | 0 | 0 | 3 |
| pregnane X nuclear receptor | 2 | 0 | 0 | 2 |
| estrogen nuclear receptor alpha | 3 | 0 | 0 | 3 |
| peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 3 | 0 | 0 | 3 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| Cellular tumor antigen p53 | 2 | 0 | 0 | 2 |
| Glutamate receptor 2 | 1 | 0 | 0 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member C4 | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member C3 | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member C2 | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member C1 | 0 | 1 | 0 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| Cocaine esterase | 0 | 1 | 0 | 1 |
| Histone deacetylase 3 | 0 | 2 | 0 | 2 |
| UDP-glucuronosyltransferase 1A9 | 0 | 0 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2A6 | 0 | 1 | 0 | 1 |
| Tissue factor | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member A1 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 2B7 | 0 | 1 | 0 | 2 |
| UDP-glucuronosyltransferase 1-6 | 0 | 0 | 0 | 1 |
| Liver carboxylesterase 1 | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member A1 | 0 | 1 | 0 | 1 |
| Histone deacetylase 4 | 0 | 2 | 0 | 2 |
| Histone deacetylase 1 | 0 | 2 | 0 | 2 |
| Aldo-keto reductase family 1 member A1 | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member B7 | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Histone deacetylase 7 | 0 | 2 | 0 | 2 |
| Histone deacetylase 2 | 0 | 2 | 0 | 2 |
| Polyamine deacetylase HDAC10 | 0 | 2 | 0 | 2 |
| Histone deacetylase 11 | 0 | 2 | 0 | 2 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| Histone deacetylase 8 | 0 | 2 | 0 | 2 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | 0 | 1 | 0 | 1 |
| Histone deacetylase 6 | 0 | 2 | 0 | 2 |
| Histone deacetylase 9 | 0 | 2 | 0 | 2 |
| Histone deacetylase 5 | 0 | 2 | 0 | 2 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |