Page last updated: 2024-12-07
wr 33278
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
WR 33278: symmetrical disulfide of WR-1065 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 115059 |
| SCHEMBL ID | 9231402 |
| MeSH ID | M0132543 |
Synonyms (16)
| Synonym |
|---|
| 58205-87-1 |
| n'-[2-[2-(3-aminopropylamino)ethyldisulfanyl]ethyl]propane-1,3-diamine |
| phosphoric acid compound with n~1~-(2-((2-((3-aminopropyl)amino)ethyl)dithio)ethyl)-1,3-propanediamine (1:1) |
| wr 33278 |
| n,n''-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine |
| unii-s8kc806h2t |
| s8kc806h2t , |
| nsc 358533 |
| 1,3-propanediamine, n,n''-(dithiodi-2,1-ethanediyl)bis- |
| wr-33278 |
| 1,3-propanediamine, n1,n1'-(dithiodi-2,1-ethanediyl)bis- |
| n-[2-[2-(3-aminopropylamino)ethyldisulfanyl]ethyl]propane-1,3-diamine |
| bis[2-(3-aminopropylamino)ethyl]disulfide |
| SCHEMBL9231402 |
| n,n'-bis-(3-amino-propyl)cystamine |
| Q27289053 |
Research Excerpts
Pharmacokinetics
| Excerpt | Reference | Relevance |
|---|---|---|
| "The pharmacokinetic properties of WR-2721 were investigated in 13 cancer patients given a 150 mg/M2 intravenous bolus dose of the drug." | ( Human pharmacokinetics of WR-2721. Bonner, HS; Glover, DJ; Kligerman, MM; Norfleet, AL; Shaw, LM; Turrisi, AT; Weiler, C, 1986) | 0.27 |
| " Validated analytic methodology to measure parent drug and pharmacologically active metabolites and pharmacokinetic studies are essential to the efficient performance and analysis of clinical studies." | ( Pharmacokinetic profile of amifostine. Bonner, H; Lieberman, R; Shaw, LM, 1996) | 0.29 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (20)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3 (15.00) | 18.7374 |
| 1990's | 13 (65.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 11.75
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (11.75) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 3 (14.29%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 18 (85.71%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||