| Assay ID | Title | Year | Journal | Article |
|---|
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID65786 | Binding towards Dopamine receptor D3 expressed in CHO-K1 cells using [3H]spiperone | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID168659 | Evaluated in rat striatum for the effect on DOPAC release and metabolism in brain dialysis model after administration of 50 umol / kg subcutaneously | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID168320 | Evaluated for rat locomotor activity in nonpretreated habituated rats at 25 umol / kg | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID169396 | Locomotory activity was determined in non pretreated rats at a dose of 3.2 umol/kg by subcutaneous administration | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID168660 | Evaluated in rat striatum for the effect on dopamine release and metabolism in brain dialysis model after administration of 50 umol / kg subcutaneously | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID176762 | In vivo DOPA accumulation in non pre-treated rat limbic system following s.c. administration. | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID227608 | Intrinsic activity against dopamine D 2 receptor | 1993 | Journal of medicinal chemistry, May-14, Volume: 36, Issue:10
| Comparison of 5-HT1A and dopamine D2 pharmacophores. X-ray structures and affinities of conformationally constrained ligands. |
| AID171017 | Change in rectal temperature induced by DiPr-5,6-ADTN at a dose of 52 umol/kg of compound by subcutaneous administration | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID168030 | Rat locomotor activity in reserpine pretreated rats and accumulated counts / 30 min is calculated | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID168121 | Evaluated for DOPA accumulation in limbic region of reserpine pretreated rat at 100 umol / kg administered intraperitoneally | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID169399 | Induced locomotor stimulation in non pre-treated rats by 52 umol/kg s.c. administration. | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID65559 | Evaluated for binding towards Dopamine receptor D2 using [3H]N-0437 as radioligand from rat striatal membrane | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID168656 | Evaluated in rat accumbens for the effect on dopamine release and metabolism in brain dialysis model after administration of 50 umol / kg subcutaneously | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID176783 | In vivo DOPA accumulation in reserpine pretreated rat striatum system by subcutaneous administration; I denotes inactive | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID63849 | Binding towards dopamine receptor D4 expressed in CHO-K1 cells using [3H]spiperone | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID62596 | Ability to displace the Dopamine receptor agonist DiPr-5,6-ADTN from rat striatal binding sites in vivo at a dose of 52 uM/kg by subcutaneous administration | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID168312 | Evaluated for rat locomotor activity in nonhabituated rats at 13 umol / kg administered intraperitoneally | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID169243 | Induced locomotor stimulation was determined in non pretreated rats at a dose of 204 umol/kg by subcutaneous administration | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID168318 | Evaluated for rat locomotor activity in nonpretreated habituated rats at 100 umol / kg | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID62591 | Ability to displace the Dopamine receptor agonist DiPr-5,6-ADTN from rat striatal binding sites in vivo at a dose of 204 uM/kg by subcutaneous administration | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID176778 | In vivo DOPA accumulation in reserpine pretreated rat limbic system by subcutaneous administration; I denotes inactive | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID168120 | Evaluated for DOPA accumulation in limbic region of nonpretreated rat at 52 umol / kg administered subcutaneously | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID176767 | In vivo DOPA accumulation in non pre-treated rat striatal system following s.c. administration. | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID171011 | Change in rectal temperature induced by DiPr-5,6-ADTN at a dose of 204 umol/kg of compound by subcutaneous administration | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID62338 | Evaluated for binding towards Dopamine receptor D2 using [3H]-spiperone as radioligand, in cloned mammalian receptors expressed in CHO-K1 cells | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID168127 | Evaluated for DOPA accumulation in striatum of nonpretreated rat at 13 umol / kg administered subcutaneously | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID168655 | Evaluated in rat accumbens for the effect on DOPAC release and metabolism in brain dialysis model after administration of 50 umol / kg subcutaneously | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID168003 | Evaluated for DOPA accumulation in limbic region of nonpretreated rat at 13 umol / kg administered subcutaneously | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID170604 | ((+)-UH-232) induced locomotor stimulation was determined in non pretreated rats at a dose of 3.2 umol/kg by subcutaneous administration | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID65560 | Binding towards Dopamine receptor D2 using [3H]spiperone from rat striatal membrane | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID62589 | In vivo displacement of DiPr-5,6-ADTN from Dopamine receptors in rat striatum | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID169246 | Induced locomotor stimulation was determined in non pretreated rats at a dose of 52 uM/kg by subcutaneous administration | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID171013 | Change in rectal temperature induced by DiPr-5,6-ADTN at a dose of 3.2 umol/kg of compound by subcutaneous administration | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID62588 | Ability to displace the Dopamine receptor agonist DiPr-5,6-ADTN from rat striatal binding sites in vivo at a dose of 13 uM/kgby subcutaneous administration | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID168311 | Evaluated for rat locomotor activity in nonhabituated rats at 100 umol / kg | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID171009 | Change in rectal temperature induced by DiPr-5,6-ADTN at a dose of 13 umol/kg of compound by subcutaneous administration | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID3480 | Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligand | 1993 | Journal of medicinal chemistry, May-14, Volume: 36, Issue:10
| Comparison of 5-HT1A and dopamine D2 pharmacophores. X-ray structures and affinities of conformationally constrained ligands. |
| AID13531 | Area under curve (AUC) is the drug concentrations in blood samples of rats with arterial catheters at 5 min and 12 hr plotted against time | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID168130 | Evaluated for DOPA accumulation in striatum of nonpretreated rat at 52 umol / kg administered subcutaneously | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID169406 | Locomotory activity was determined in reserpine pretreated rats at a dose of 52 umol/kg by subcutaneous administration. Value is the accumulation counts/30 min | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID168131 | Evaluated for DOPA accumulation in striatum of reserpine pretreated rat at 100 umol / kg administered intraperitoneally | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID65415 | Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligand | 1993 | Journal of medicinal chemistry, May-14, Volume: 36, Issue:10
| Comparison of 5-HT1A and dopamine D2 pharmacophores. X-ray structures and affinities of conformationally constrained ligands. |
| AID169242 | Induced locomotor stimulation in non pre-treated rats by 13 umol/kg s.c. administration. | 1987 | Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
| Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. |
| AID62337 | Binding towards Dopamine receptor D2 expressed in CHO-K1 cells using [3H]U-86170 | 1993 | Journal of medicinal chemistry, Oct-15, Volume: 36, Issue:21
| Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. |
| AID62743 | Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligand | 1993 | Journal of medicinal chemistry, May-14, Volume: 36, Issue:10
| Comparison of 5-HT1A and dopamine D2 pharmacophores. X-ray structures and affinities of conformationally constrained ligands. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |