Page last updated: 2024-11-13

laidlomycin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

laidlomycin: polycyclic, polyether, monocarboxylic acid posessing inhibitory activity against various Mycoplasma species, especially Acholeplasma laidlawii; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID71454116
CHEMBL ID2205250
MeSH IDM0055540

Synonyms (28)

Synonym
16-deethyl-3-o-demethyl-16-methyl-3-o-(1-oxopropyl)monensin
brn 1675244
laidlomycin
laidlomycin [inn:ban]
laidlomicina [inn-spanish]
einecs 260-095-1
laidlomycine [inn-french]
monensin, 16-deethyl-3-o-demethyl-16-methyl-3-o-(1-oxopropyl)-
laidlomycinum [inn-latin]
56283-74-0
CHEMBL2205250
unii-mi3s6zf5qe
mi3s6zf5qe ,
laidlomycine
laidlomicina
laidlomycinum
laidlomycin [inn]
laidlomycin [mi]
ZNBNBTIDJSKEAM-NISBWGIBSA-N
Q15725701
(2s,3r,4r)-4-[(2s,5r,7s,8r,9s)-7-hydroxy-2-[(2r,5s)-5-[(2r,3s,5r)-5-[(2s,3s,5r,6r)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-2-methyl-3-propanoyloxypentanoic a
DTXSID401024015
laidlomicina (inn-spanish)
laidlomycinum (inn-latin)
csu-1
16-deethyl-3-o-demethyl-16-methyl-3-o-(1-oxopropyl) monensin
laidlomycine (inn-french)
AKOS040746980

Research Excerpts

Compound-Compound Interactions

ExcerptReferenceRelevance
"The objective of this research was to use data from multiple studies to comprehensively quantify the effects of feeding 1) laidlomycin propionate (LP), alone and/or in combination with chlortetracycline, compared with 2) monensin sodium (MS), alone and/or in combination with tylosin, at commercially approved dosages, on ADG, DMI, feed efficiency (FE), mortality, and carcass characteristics (HCW and liver abscesses)."( Meta-analysis of the effects of laidlomycin propionate, fed alone or in combination with chlortetracycline, compared with monensin sodium, fed alone or in combination with tylosin, on growth performance, health, and carcass outcomes in finishing steers in
Branine, M; Cernicchiaro, N; Corbin, M; Prouty, F; Quinn, M; Renter, DG, 2016
)
0.92

Dosage Studied

ExcerptRelevanceReference
"75% BW) or steers were dosed intraruminally with a 100% concentrate diet."( Efficacy of laidlomycin propionate to reduce ruminal acidosis in cattle.
Bauer, ML; Britton, RA; Herold, DW; Klopfenstein, TJ; Stock, RA; Yates, DA, 1995
)
0.67
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID716395Potentiation of colchicine-induced cytotoxicity in human KB-C4 cells at 1 ug/mL relative to control2012Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23
Polyether ionophores-promising bioactive molecules for cancer therapy.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (27)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (22.22)18.7374
1990's8 (29.63)18.2507
2000's9 (33.33)29.6817
2010's4 (14.81)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 24.57

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index24.57 (24.57)
Research Supply Index3.47 (2.92)
Research Growth Index4.49 (4.65)
Search Engine Demand Index22.84 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (24.57)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials2 (6.90%)5.53%
Reviews2 (6.90%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other25 (86.21%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]