Page last updated: 2024-12-10

isoplumericin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

isoplumericin: isolated from Plumeria rubra [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
PlumeriagenusA plant genus of the family APOCYNACEAE that contains plumericin, uleine and demethoxyaspidospermine.[MeSH]ApocynaceaeThe dogbane family of the order Gentianales. Members of the family have milky, often poisonous juice, smooth-margined leaves, and flowers in clusters.[MeSH]
Plumeria rubraspecies[no description available]ApocynaceaeThe dogbane family of the order Gentianales. Members of the family have milky, often poisonous juice, smooth-margined leaves, and flowers in clusters.[MeSH]

Cross-References

ID SourceID
PubMed CID5281543
CHEBI ID6042
MeSH IDM0506488

Synonyms (6)

Synonym
31298-76-7
isoplumericin
chebi:6042 ,
Q27107001
methyl (1s,4s,8r,10s,11z,14s)-11-ethylidene-12-oxo-7,9,13-trioxatetracyclo[6.5.1.01,10.04,14]tetradeca-2,5-diene-5-carboxylate
DTXSID801317662
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
terpene lactone
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (8)

Assay IDTitleYearJournalArticle
AID338971Cytotoxicity against human 9KB cells
AID1514104Antileishmanial activity against Leishmania donovani amastigotes infected in mouse J774G8 cells after 48 to 72 hrs by Giemsa staining-based bright-field microscopic analysis2018European journal of medicinal chemistry, Dec-05, Volume: 160Leishmania treatment and prevention: Natural and synthesized drugs.
AID338972Antileukemic activity against mouse P388 cells xenografted in mouse
AID338725Toxicity in brine shrimp
AID1514103Antileishmanial activity against Leishmania donovani promastigotes after 48 hrs by MTT assay2018European journal of medicinal chemistry, Dec-05, Volume: 160Leishmania treatment and prevention: Natural and synthesized drugs.
AID334066Antimicrobial activity against yeast Sc71997Journal of natural products, Dec, Volume: 60, Issue:12
Bioactive iridoids and a new lignan from Allamanda cathartica and Himatanthus fallax from the Suriname rainforest.
AID338973Antitumor activity against Agrobacterium tumefaciens-induced crown gall tumor in potato tubers by potato disk assay
AID334065Cytotoxicity against mouse M109 cells1997Journal of natural products, Dec, Volume: 60, Issue:12
Bioactive iridoids and a new lignan from Allamanda cathartica and Himatanthus fallax from the Suriname rainforest.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.52

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.52 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.92 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.52)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]