Page last updated: 2024-11-04

hydantoin-5-propionic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

hydantoin-5-propionic acid: metabolite of histidine [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

hydantoin-5-propionic acid : A imidazolidine-2,4-dione that is hydantoin substituted by a 2-carboxyethyl group at position 4. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID782
CHEBI ID28297
SCHEMBL ID762369
MeSH IDM0143814

Synonyms (36)

Synonym
HMS1674G01
4-imidazolidinepropanoic acid, 2,5-dioxo-
nsc23606
nsc-23606
5624-26-0
OPREA1_558366
STK500619
OPREA1_310966
hydantoin-propionate
C05565
3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid
3-(2,5-dioxoimidazolidin-4-yl)propanoic acid
F12EE0DB-5021-4304-8031-B80E29A5C359
AKOS000266619
3-(2,5-dioxo-1,3-diazolidin-4-yl)propanoic acid
EN300-10554
CHEBI:28297
3-(2,5-dioxo-4-imidazolidinyl)propanoic acid
1-(2,4-(3h,5h)imidazoledione)propionic acid
hydantoin-5-propionic acid
nsc 23606
FT-0676687
AKOS016037530
SCHEMBL762369
mfcd02737984
CS-0084874
(+/-)-5-hydantoinpropionic acid
VWFWNXQAMGDPGG-UHFFFAOYSA-N
Q27103620
D74592
3-(2,5-dioxoimidazolidin-4-yl)propanoicacid
SB46742
A924022
2,5-dioxo-4-imidazolidinepropanoic acid
DTXSID50863581
Z56347438
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
metaboliteAny intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
mouse metaboliteAny mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
imidazolidine-2,4-dioneAn imidazolidinone with oxo groups at position 2 and 4.
monocarboxylic acidAn oxoacid containing a single carboxy group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (1)

PathwayProteinsCompounds
Biochemical pathways: part I0466

Bioassays (2)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.26

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.26 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.71 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.26)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (14.29%)4.05%
Observational0 (0.00%)0.25%
Other6 (85.71%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]