Page last updated: 2024-10-06

Estrogen metabolism

Proteins (0)

Compounds (19)

CompoundDescription
estrone sulfatesulfoconjugated estrone; RN given refers to parent cpd
SuperoxidesHighly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.
estroneAn aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
1,5(10)-estradiene-3,4,17-trionestructure given in first source
16 alpha-hydroxyestrone
estra-1(10),4-diene-2,3,17-trionestructure given in first source
2-hydroxyestradiolcatechol estrogen; RN given refers to (17 beta)-isomer
2-hydroxyestronecatechol estrogen which is a major metabolite of estradiol in man & animals; RN given refers to parent cpd
2-methoxyestrone
estradiol-3-glucuronideRN given refers to (beta-D)-glucopyranosiduronic acid (17beta)-isomer
2-methoxyestrone-3-glucuronide
estradiol-17 beta-glucuronideRN given refers to (beta-D)-isomer of glucopyranosiduronic acid
4-hydroxyestradiolcatechol estrogen
estradiol-3-sulfateRN given refers to (17beta)-isomer
4-hydroxyestrone
estrone-3-glucuronide
4-hydroxyestrone-4-methyl ether
2-methoxyestradiolA metabolite of estradiol that lacks estrogenic activity and inhibits TUBULIN polymerization. It has antineoplastic properties, including inhibition of angiogenesis and induction of APOPTOSIS.