Page last updated: 2024-10-06
Estrogen metabolism
Proteins (0)
Compounds (19)
| Compound | Description |
|---|---|
| estrone sulfate | sulfoconjugated estrone; RN given refers to parent cpd |
| Superoxides | Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides. |
| estrone | An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women. |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| 1,5(10)-estradiene-3,4,17-trione | structure given in first source |
| 16 alpha-hydroxyestrone | |
| estra-1(10),4-diene-2,3,17-trione | structure given in first source |
| 2-hydroxyestradiol | catechol estrogen; RN given refers to (17 beta)-isomer |
| 2-hydroxyestrone | catechol estrogen which is a major metabolite of estradiol in man & animals; RN given refers to parent cpd |
| 2-methoxyestrone | |
| estradiol-3-glucuronide | RN given refers to (beta-D)-glucopyranosiduronic acid (17beta)-isomer |
| 2-methoxyestrone-3-glucuronide | |
| estradiol-17 beta-glucuronide | RN given refers to (beta-D)-isomer of glucopyranosiduronic acid |
| 4-hydroxyestradiol | catechol estrogen |
| estradiol-3-sulfate | RN given refers to (17beta)-isomer |
| 4-hydroxyestrone | |
| estrone-3-glucuronide | |
| 4-hydroxyestrone-4-methyl ether | |
| 2-methoxyestradiol | A metabolite of estradiol that lacks estrogenic activity and inhibits TUBULIN polymerization. It has antineoplastic properties, including inhibition of angiogenesis and induction of APOPTOSIS. |