sulfurous acid, 2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethyl ester profile

Description

sulfurous acid, 2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethyl ester: structure in Merck Index, 9th ed, #797 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	8809
CHEMBL ID	1903447
CHEBI ID	82151
SCHEMBL ID	434557
MeSH ID	M0046083

Synonyms (113)

Synonym
2-chloroethyl 2-{[4-(1,1-dimethylethyl)phenyl]oxy}-1-methylethyl sulfite
caswell no. 131
ethanol, 2-chloro-, 2-(p-t-butylphenoxy)-1-methylethyl sulfite
2-(p-t-butylphenoxy)-1-methylethyl 2-chloroethyl ester of sulphurous acid
ai3-16519
2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethylsulfite
2-(4-t-butylphenoxy)isopropyl-2-chloroethyl sulfite
nsc 404155
2-(p-t-butylphenoxy)-1-methylethyl-2-chloroethyl sulfite
ester of 2-chloroethanol with 2-(p-tert-butylphenoxy)-methyl sulphite
2-chloroethyl 1-methyl-2-(p-t-butylphenoxy)ethyl sulphate
sulfurous acid, 2-(p-t-butylphenoxy)-1-methylethyl-2-chloroethyl ester
2-chloroethyl 2-(4-(1,1-dimethylethyl)phenoxy)-1-methylethyl sulfite
epa pesticide chemical code 062501
2-chloroethyl sulphite of 1-(p-tert-butylphenoxy)-2-propanol
hsdb 1529
2-(p-t-butylphenoxy)isopropyl 2'-chloroethyl sulphite
aramiteararamite-15w
beta-chloroethyl-beta'-(p-t-butylphenoxy)-alpha'-methylethyl sulfite
2-(p-terc.butylfenoxy)isopropyl-2'-chlorethylester kyseliny siricite [czech]
brn 2509312
2-chloroethyl sulphite of 1-(p-t-butylphenoxy)-2-propanol
2-p-tert-butylphenoxyisopropyl 2-chloroethyl sulfite
2-(4-tert-butylphenoxy)-1-methylethyl 2-chloroethyl sulfite
butylphenoxyisopropyl chloroethyl sulfite
2-propanol, 1-(p-t-butylphenoxy)-, 2-chloroethyl sulfite
beta-chloroethyl-beta-(p-t-butylphenoxy)-alpha-methylethyl sulphite
2-(4-tert-butylphenoxy)isopropyl 2-chloroethyl sulfite
2-propanol, 1-(p-tert-butylphenoxy)-, 2-chloroethyl sulfite
ethanol, 2-chloro-, ester with 2-(p-tert-butylphenoxy)-1-methylethyl sulfite
2-(p-t-butylphenoxy)isopropyl-2'-chloroethyl sulphite
sulfurous acid, 2-chloroethyl 2-(4-(1,1-dimethylethyl)phenoxy)-1-methylethyl ester
2-(p-t-butylphenoxy)-1-methylethyl sulphite of 2-chloroethanol
2-(p-t-butylphenoxy)-1-methylethyl 2'-chloroethyl sulphite
beta-chloroethyl-beta-(p-tert-butylphenoxy)-alpha-methylethyl sulphite
88-r
ccris 51
sulfurous acid, 2-chloroethyl 2-[4-(1,1-dimethylethyl)phenoxy]-1-methylethyl ester
2-(p-butylphenoxy)isopropyl 2-chloroethyl sulfite
2-(p-tert-butylphenoxy)-1-methylethyl sulfite of 2-chloroethanol
butylphenoxyisopropyl chloroethyl sulfite@ces
2-(p-t-butylphenoxy)isopropyl 2'-chloroethyl sulfite
aratron
2-(p-tert-butylphenoxy)-1-methylethyl 2'-chloroethyl sulfite
2-chloroethyl 1-methyl-2-(p-tert-butylphenoxy)ethyl sulfite
2-(p-tert-butylphenoxy)isopropyl 2-chloroethyl sulfite
niagaramite
2-propanol, 2-chloroethyl sulfite
140-57-8
.beta.-chloroethyl-.beta.-(p-t-butylphenoxy)-.alpha.'-methylethyl sulfite
2-(p-tert-butylphenoxy)-1-methylethyl-2-choroethyl sulfite
2-chloroethyl sulfite of 1-(p-t-butylphenoxy)-2-propanol
aracide
ethanol, ester with 2-(p-tert-butylphenoxy)-1-methylethyl sulfite
sulfurous acid,1-dimethylethyl)phenoxy]-1-methylethyl ester
88r ,
compound 88r
aramite-15w
2-(4-t-butylphenoxy)isopropyl-2-chloroethyl sulphite
sulfurous acid, 2-(p-tert-butylphenoxy)-1-methylethyl-2-chloroethyl ester
CES ,
.beta.-chloroethyl-.beta.-(p-t-butylphenoxy)-.alpha.-methylethyl sulfite
aramit
ent 16,519
nsc404155
wln: g2oso & oy1 & 1or dx1 & 1 & 1
nsc-404155
sulfurous acid, 2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethyl ester
aramite
2-(p-butylphenoxy)-1-methylethyl 2-chloroethyl sulfite
2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethyl ester of sulfurous acid
acaracide
ortho-mite
2-(p-tert-buytlphenoxy)isopropyl 2-chloroethyl sulfite
ethanol, 2-(p-tert-butylphenoxy)-1-methylethyl sulfite
2-(4-tert-butylphenoxy)isopropyl-2-chloroethyl sulfite
NCGC00163773-01
1-(4-tert-butylphenoxy)propan-2-yl 2-chloroethyl sulfite
NCGC00163773-02
C19019
NCGC00257952-01
dtxsid3020097 ,
cas-140-57-8
tox21_200398
dtxcid3097
55619r6x8s ,
4-06-00-03301 (beilstein handbook reference)
unii-55619r6x8s
2-(p-terc.butylfenoxy)isopropyl-2'-chlorethylester kyseliny siricite
FT-0602873
AKOS015888307
(rs)-2-(4-tert-butylphenoxy)-1-methylethyl 2-chloroethyl sulfite
aramite [mi]
aramite [hsdb]
SCHEMBL434557
CHEBI:82151 ,
2-(4-tert-butylphenoxy)-1-methylethyl 2-chloroethyl sulfite #
ethanol, 2-chloro-, 2-(p-tert-butylphenoxy)-1-methylethyl sulfite
.beta.-chloroethyl-.beta.'-(p-tert-butylphenoxy)-.alpha.'-methylethyl sulfite
.beta.-chloroethyl-.beta.'-(p-t-butylphenoxy)-.alpha.'-methylethyl sulfite
2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethyl sulfite
YKFRAOGHWKADFJ-UHFFFAOYSA-N
CHEMBL1903447
sulfurous acid,2-chloroethyl 2-[4-(1,1-dimethylethyl)phenoxy]-1-methylethyl ester
aramite 10 microg/ml in isooctane
J-007404
aramite 2000 microg/ml in n-hexane
Q27155771
brn2509312
brn-2509312
CS-0077955
1ST22684
HY-119766

Drug Classes (1)

Class	Description
alkylbenzene	A monocyclic arene that is benzene substituted with one or more alkyl groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (16)

Potency Measurements

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
RAR-related orphan receptor gamma	Mus musculus (house mouse)	Potency	24.4603	0.0060	38.0041	19,952.5996	AID1159521
GLI family zinc finger 3	Homo sapiens (human)	Potency	2.1945	0.0007	14.5928	83.7951	AID1259368; AID1259369
AR protein	Homo sapiens (human)	Potency	1.3686	0.0002	21.2231	8,912.5098	AID1259243; AID588515
nuclear receptor subfamily 1, group I, member 3	Homo sapiens (human)	Potency	1.7317	0.0010	22.6508	76.6163	AID1224838
progesterone receptor	Homo sapiens (human)	Potency	14.5883	0.0004	17.9460	75.1148	AID1346784; AID1346795
glucocorticoid receptor [Homo sapiens]	Homo sapiens (human)	Potency	5.6234	0.0002	14.3764	60.0339	AID588533
retinoic acid nuclear receptor alpha variant 1	Homo sapiens (human)	Potency	3.8767	0.0030	41.6115	22,387.1992	AID1159552
retinoid X nuclear receptor alpha	Homo sapiens (human)	Potency	7.0795	0.0008	17.5051	59.3239	AID588544
estrogen-related nuclear receptor alpha	Homo sapiens (human)	Potency	0.9056	0.0015	30.6073	15,848.9004	AID1224841; AID1224842; AID1224848; AID1224849
pregnane X nuclear receptor	Homo sapiens (human)	Potency	17.4283	0.0054	28.0263	1,258.9301	AID1346982; AID720659
estrogen nuclear receptor alpha	Homo sapiens (human)	Potency	38.1966	0.0002	29.3054	16,493.5996	AID1259244; AID588513; AID588514
peroxisome proliferator activated receptor gamma	Homo sapiens (human)	Potency	26.6514	0.0010	19.4141	70.9645	AID588536; AID588537
nuclear factor NF-kappa-B p105 subunit isoform 1	Homo sapiens (human)	Potency	50.1187	4.4668	24.8329	44.6684	AID651749
nuclear factor erythroid 2-related factor 2 isoform 1	Homo sapiens (human)	Potency	32.9384	0.0006	27.2152	1,122.0200	AID651741; AID720636
Voltage-dependent calcium channel gamma-2 subunit	Mus musculus (house mouse)	Potency	1.3755	0.0015	57.7890	15,848.9004	AID1259244
Glutamate receptor 2	Rattus norvegicus (Norway rat)	Potency	1.3755	0.0015	51.7393	15,848.9004	AID1259244
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Ceullar Components (1)

Process	via Protein(s)	Taxonomy
plasma membrane	Glutamate receptor 2	Rattus norvegicus (Norway rat)
[Information is prepared from geneontology information from the June-17-2024 release]

Research

Studies (7)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	6 (85.71)	18.7374
1990's	1 (14.29)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	1 (11.11%)	4.05%
Observational	0 (0.00%)	0.25%
Other	8 (88.89%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Description	Relationhip Strength	Studies	Classes	Roles
sulfites	[no description available]	medium	3	divalent inorganic anion; sulfur oxide; sulfur oxoanion
fenazox	[no description available]	medium	1	azoxy compound
tyrphostin ag 1024	[no description available]	low	0	alkylbenzene
benzethonium	[no description available]	low	0	alkylbenzene
isoxsuprine	[no description available]	low	0	alkylbenzene
nylidrin	[no description available]	low	0	alkylbenzene
oxeladin	[no description available]	low	0	alkylbenzene
2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanol	[no description available]	low	0	alkylbenzene
octoxynol	[no description available]	low	0	alkylbenzene
tyrphostin a9	[no description available]	low	0	alkylbenzene	geroprotector
valethamate	[no description available]	low	0	alkylbenzene
xylometazoline	[no description available]	low	0	alkylbenzene
hydroxyphenamate	[no description available]	low	0	alkylbenzene
isoaminile	[no description available]	low	0	alkylbenzene
phenaglycodol	[no description available]	low	0	alkylbenzene
p-tert-amylphenol	[no description available]	low	0	alkylbenzene
2-tert-butylphenol	[no description available]	low	0	alkylbenzene
2,6-di-tert-butyl-4-hydroxymethylphenol	[no description available]	low	0	alkylbenzene
2,4-di-tert-butylphenol	[no description available]	low	0	alkylbenzene; phenols	antioxidant; bacterial metabolite; marine metabolite
4-tert-butylbenzoic acid	[no description available]	low	0	alkylbenzene
cumene	[no description available]	low	0	alkylbenzene
ethylbenzene	[no description available]	low	0	alkylbenzene
n-propylbenzene	[no description available]	low	0	alkylbenzene
n-butylbenzene	[no description available]	low	0	alkylbenzene
proxazole	[no description available]	low	0	alkylbenzene
sec-butylbenzene	[no description available]	low	0	alkylbenzene
4-tert-octylphenol	[no description available]	low	0	alkylbenzene
crufomate	[no description available]	low	0	alkylbenzene
isoxsuprine hydrochloride	[no description available]	low	0	alkylbenzene
4-propylphenol	[no description available]	low	0	alkylbenzene
promecarb	[no description available]	low	0	alkylbenzene
o-cymen-5-ol	[no description available]	low	0	alkylbenzene
butethamate citrate	[no description available]	low	0	alkylbenzene
butamirate	[no description available]	low	0	alkylbenzene
2,6-di-tert-butylphenol	[no description available]	low	0	alkylbenzene; phenols	antioxidant
lifibrol	[no description available]	low	0	alkylbenzene
ephedrine hydrochloride	[no description available]	low	0	alkylbenzene
simetride	[no description available]	low	0	alkylbenzene
fenoxazoline	[no description available]	low	0	alkylbenzene
tris-(2,4-di-tert-butylphenyl) phosphite	[no description available]	low	0	alkylbenzene
fenpropimorph	[no description available]	low	0	alkylbenzene
2-(n-myristoylamino)-1-phenyl-1-propanol	[no description available]	low	0	alkylbenzene
3-(2-hydroxy-4-(1,1-dimethylheptylphenyl)cyclohexan-1-ol)	[no description available]	low	0	alkylbenzene; ring assembly
4-propylbenzoic acid	[no description available]	low	0	alkylbenzene
2-n-hexyl-5-n-propylresorcinol	[no description available]	low	0	alkylbenzene
4-[[bis(2-hydroxyethyl)amino]methyl]-2,6-ditert-butylphenol	[no description available]	low	0	alkylbenzene
(1S,2R)-2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanol	[no description available]	low	0	alkylbenzene
oxilofrine	[no description available]	low	0	alkylbenzene
2-[(dimethylamino)methyl]-4-methyl-6-(1-methylcyclohexyl)phenol	[no description available]	low	0	alkylbenzene; ring assembly
1-(1-azepanyl)-2-(2-bromo-4-propan-2-ylphenoxy)ethanone	[no description available]	low	0	alkylbenzene
N-[5-(4-tert-butylphenyl)-1,3,4-thiadiazol-2-yl]-2-methoxyacetamide	[no description available]	low	0	alkylbenzene
4-(4-tert-butylphenoxy)-N-(4,5-dihydrothiazol-2-yl)butanamide	[no description available]	low	0	alkylbenzene
2-(2-bromo-4-tert-butylphenoxy)-N-(2-furanylmethyl)acetamide	[no description available]	low	0	alkylbenzene
N-[[[2-(2-bromo-4-propan-2-ylphenoxy)-1-oxoethyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamide	[no description available]	low	0	alkylbenzene
N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-propan-2-ylphenyl) ester	[no description available]	low	0	alkylbenzene
N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-tert-butylphenyl) ester	[no description available]	low	0	alkylbenzene
3-(4-tert-butylphenoxy)-N-(4,5-dihydrothiazol-2-yl)propanamide	[no description available]	low	0	alkylbenzene
2-[[2-[[5-(4-tert-butylphenyl)-2-methoxycarbonyl-3-thiophenyl]amino]-2-oxoethyl]thio]acetic acid	[no description available]	low	0	alkylbenzene
1-(4-tert-butylphenoxy)-3-(1H-1,2,4-triazol-5-ylthio)-2-propanol	[no description available]	low	0	alkylbenzene
N-(2-methoxycyclohexyl)-2,5-dimethylaniline	[no description available]	low	0	alkylbenzene
tinofedrine	[no description available]	low	0	alkylbenzene
fospropofol	[no description available]	low	0	alkylbenzene
cgp 13501	[no description available]	low	0	alkylbenzene
3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol	[no description available]	low	0	alkylbenzene; ring assembly
cgp 7930	[no description available]	low	0	alkylbenzene
nylidrin hydrochloride	[no description available]	low	0	alkylbenzene
methylbenzethonium chloride	[no description available]	low	0	alkylbenzene
tapentadol	[no description available]	low	0	alkylbenzene
o-demethyltramadol	[no description available]	low	0	alkylbenzene; ring assembly
elsibucol	[no description available]	low	0	alkylbenzene
2-(4-butan-2-ylanilino)-3-pyridinecarbonitrile	[no description available]	low	0	alkylbenzene
oxaziclomefone	[no description available]	low	0	alkylbenzene

Condition	Relationship Strength	Studies
Acariasis	low	2
Cancer of Liver	low	1
Cancer of the Liver	low	1
Cancer, Hepatocellular	low	1
Canine Diseases	low	1
Disease	low	1
Dog Diseases	low	1
Hepatic Cancer	low	1
Hepatic Neoplasms	low	1
Hepatocellular Cancer	low	1
Liver Cancer	low	1
Liver Neoplasms	low	1
Mange	low	2
Mange, Sarcoptic	low	1
Mite Infestations	low	2
Neoplasms, Hepatic	low	1
Neoplasms, Liver	low	1
Rodent Diseases	low	1
Scabies	low	1

sulfurous acid, 2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethyl ester