Assay ID | Title | Year | Journal | Article |
AID1571664 | Agonist activity at rat mGlu7 receptor expressed in HEK cell co-expressing Galpha15 (unknown origin) assessed as reduction in intracellular Ca2+ mobilization by Fluo-4-AM dye based fluorescence assay | 2019 | MedChemComm, Feb-01, Volume: 10, Issue:2
| Progress toward allosteric ligands of metabotropic glutamate 7 (mGlu7) receptor: 2008-present. |
AID1571663 | Agonist activity at human mGlu4 expressed in CHO cells co-expressing Gqi5 (unknown origin) assessed as reduction in intracellular Ca2+ levels by Fluo-4-AM dye based fluorescence assay | 2019 | MedChemComm, Feb-01, Volume: 10, Issue:2
| Progress toward allosteric ligands of metabotropic glutamate 7 (mGlu7) receptor: 2008-present. |
AID1571665 | Agonist activity at rat mGlu8 receptor expressed in HEK cell co-expressing Galpha15 (unknown origin) assessed as reduction in intracellular Ca2+ mobilization by Fluo-4-AM dye based fluorescence assay | 2019 | MedChemComm, Feb-01, Volume: 10, Issue:2
| Progress toward allosteric ligands of metabotropic glutamate 7 (mGlu7) receptor: 2008-present. |
AID1492913 | Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium flux incubated for 142 secs followed by glutamate addition measured after 120 secs by Fluo4-AM dye based f | 2017 | ACS medicinal chemistry letters, Oct-12, Volume: 8, Issue:10
| Discovery of VU6005649, a CNS Penetrant mGlu |
AID1492915 | Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium flux incubated for 142 secs followed by glutamate addition measured after 120 secs by Fluo4-AM dye based f | 2017 | ACS medicinal chemistry letters, Oct-12, Volume: 8, Issue:10
| Discovery of VU6005649, a CNS Penetrant mGlu |
AID1492909 | Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mobilization incubated for 142 secs followed by glutamate addition measured after 120 secs by Fluo4-AM dye b | 2017 | ACS medicinal chemistry letters, Oct-12, Volume: 8, Issue:10
| Discovery of VU6005649, a CNS Penetrant mGlu |
AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6
| A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | | | |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |