arsenocholine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

arsenocholine : An arsonium ion that is choline in which the central nitrogen has been replaced by arsenic. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID Source	ID
PubMed CID	104820
CHEBI ID	134092
MeSH ID	M0119162

Synonyms (13)

Synonym
(2-hydroxyethyl)trimethylarsonium
arsonium, (2-hydroxyethyl)trimethyl-
arsenocholine
CHEBI:134092
(2-hydroxyethyl)(trimethyl)arsanium
39895-81-3
unii-agj7rv2d8p
agj7rv2d8p ,
(2-hydroxyethyl)trimethyl-arsonium
DTXSID80873153
Q704767
arsenocholine standard solution
(2-hydroxyethyl)trimethylarsanium

Research Excerpts

Bioavailability

Excerpt	Reference	Relevance
"The aim of this study was to evaluate the bioavailability of arsenic (As) through cultured oyster Crassostrea gigas and Crassostrea corteziensis from four coastal lagoons (SE Gulf of California)."	( Arsenic and arsenic species in cultured oyster (Crassostrea gigas and C. corteziensis) from coastal lagoons of the SE Gulf of California, Mexico. Bergés-Tiznado, ME; Notti, A; Páez-Osuna, F; Regoli, F, 2013)	0.39

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (3)

Role	Description
marine metabolite	Any metabolite produced during a metabolic reaction in marine macro- and microorganisms.
xenobiotic	A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
human urinary metabolite	Any metabolite (endogenous or exogenous) found in human urine samples.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

Class	Description
arsonium ion	Arsonium, AsH4(+), and derivatives formed by substitution by univalent groups.
organoarsenic compound
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (30)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	7 (23.33)	18.7374
1990's	4 (13.33)	18.2507
2000's	4 (13.33)	29.6817
2010's	10 (33.33)	24.3611
2020's	5 (16.67)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 27.17

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	27.17 (24.57)
Research Supply Index	3.43 (2.92)
Research Growth Index	4.91 (4.65)
Search Engine Demand Index	27.81 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (27.17)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	30 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
arsenic acid arsenic acid: RN given refers to orthoarsenic acid(H3AsO4); see also sodium arsenate. arsenic acid : An arsenic oxoacid comprising one oxo group and three hydroxy groups attached to a central arsenic atom.	3.33	5	arsenic oxoacid	Escherichia coli metabolite
choline [no description available]	7.93	4	cholines	allergen; Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; neurotransmitter; nutrient; plant metabolite; Saccharomyces cerevisiae metabolite
chlorine chloride : A halide anion formed when chlorine picks up an electron to form an an anion.	1.99	1	halide anion; monoatomic chlorine	cofactor; Escherichia coli metabolite; human metabolite
arsenous acid arsenous acid : An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.	2.6	1	arsenic oxoacid
cacodylic acid dimethylarsinic acid : The organoarsenic compound that is arsenic acid substituted on the central arsenic atom with two methyl groups.	3.93	12	organoarsenic compound	xenobiotic metabolite
ether Ether: A mobile, very volatile, highly flammable liquid used as an inhalation anesthetic and as a solvent for waxes, fats, oils, perfumes, alkaloids, and gums. It is mildly irritating to skin and mucous membranes.. ether : An organooxygen compound with formula ROR, where R is not hydrogen.. diethyl ether : An ether in which the oxygen atom is linked to two ethyl groups.	2.02	1	ether; volatile organic compound	inhalation anaesthetic; non-polar solvent; refrigerant
monomethylarsonic acid monomethylarsonic acid: structure given in first source	3.84	11	arsonic acids; one-carbon compound; organoarsonic acid
tetramethylarsonium tetramethylarsonium: RN given refers to parent cpd	7.69	3
arsenobetaine [no description available]	4.55	24	organic salt
trimethylarsine trimethylarsine : An arsine that is arsane in which each of the hydrogens is substituted by a methyl group.	1.97	1	arsine
trimethylarsine oxide trimethylarsine oxide: sodium arsenate metabolite in fish	2.41	2	arsine oxides
arsenic Arsenic: A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)	4.77	30	metalloid atom; pnictogen	micronutrient
phosphatidylcholines Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.	2.06	1	1,2-diacyl-sn-glycero-3-phosphocholine

Condition	Relationship Strength	Studies
HPV Infection [description not available]	2.6	1
Papillomavirus Infections Neoplasms of the skin and mucous membranes caused by papillomaviruses. They are usually benign but some have a high risk for malignant progression.	2.6	1
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	2.08	1

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